Sentences with phrase «obesity related genes»

Not exact matches

Habit then uses blood samples and DNA from a cheek swab to glean details on glucose levels and obesity - related genes, among other factors that could affect metabolism.

«We wanted to find out if obesity - related genes and activity level have an interactive effect on obesity risk — if there is a «double whammy» effect of being both at genetic risk and physically inactive, beyond the additive effect of these factors,» said Dr. Wood.

Mice without the leptin gene, called ob / ob, overeat, weigh in at three to four times normal, and develop symptoms similar to the obesity - related diabetes seen in humans.

«In the current study, we analyzed dozens of variants of those genes and other genes frequently associated with obesity risk and saw that, while total fat intake was related to higher BMI, people who were genetically predisposed to obesity and ate the most saturated fat had the highest BMIs.»

Each obesity - related gene affects a different aspect of weight control.

«Finding the genes that increase risk of obesity is only the end of the beginning,» says senior author Ruth Loos, Ph.D., professor of preventive medicine at Mt. Sinai Hospital, and director of the Genetics of Obesity and related Metabolic Traits Program in the Charles Bronfman Institute for Personalized Meobesity is only the end of the beginning,» says senior author Ruth Loos, Ph.D., professor of preventive medicine at Mt. Sinai Hospital, and director of the Genetics of Obesity and related Metabolic Traits Program in the Charles Bronfman Institute for Personalized MeObesity and related Metabolic Traits Program in the Charles Bronfman Institute for Personalized Medicine.

A better understanding of their functions related to body fat and obesity could provide a better picture of the roles these genes play in a variety of diseases.

Three of the genes seemed to be related to overall obesity.

To identify genes whose expression correlated with adiposity, we profiled gene expression in perigonadal adipose tissue from 24 mice in which adiposity varied due to sex, diet, and the obesity - related mutations agouti (Ay) and obese (Lepob).

They describe gene therapy administered through skin transplants to treat two related and extremely common human ailments: type - 2 diabetes and obesity.

«Finding a SIRT3 gene mutation linked to metabolic syndrome is a big step towards developing treatments for this increasingly common collection of obesity - related illnesses,» said Dr. Verdin, who is also a UCSF professor of medicine.

Mariman EC, Bouwman FG, Aller EE, van Baak MA, Wang P. Extreme obesity is associated with variation in genes related to the circadian rhythm of food intake and hypothalamic signaling.

Striking sex and regional differences in the increase of obesity - related T2DM prevalence developed throughout the last 3 decades, reflecting complex relationships with differences in ethnicity, migration, culture, lifestyle, gene - environment interactions, socioeconomic status (SES) and social roles (12).

In one study of 23 overweight and healthy men engaged in a six month program of exercise, 108 minutes of exercise a week changed the expression of about a third of the genes in their fat cells, including some that relate to the risk of type 2 diabetes and the development of obesity.

However, the good news is that according to the 2011 study even moderate physical activity such as walking is able to reduce the negative influence of this obesity - related gene variation by more than 25 %!

Watching TV for two hours each day increases the effect of certain obesity - related genes by as much as 25 %, the researchers estimate.

The team honed in on three obesity - related genes to study (the genes they chose have all been shown to affect human weight).