SPIROMICS 2, a five - year extension of the original project, has three main
objectives: track the progression of people who show symptoms of COPD but do not meet the
criteria for
diagnosis; determine whether the biological root of emphysema is a problem with the lung's airways or blood vessels; and understand the biology of COPD exacerbation, a sudden worsening of bronchitis symptoms.
Objective: Recently, changes have been proposed to DSM - IV diagnostic
criteria for posttraumatic stress disorder (PTSD) to refine the
diagnosis because of concerns about its construct validity.