Sentences with phrase «objective response rate of»

Patients whose tumors had a normal BRAF gene showed an overall objective response rate of 61 %.

Not exact matches

The biotech specialist said that its updated phase 2 data in a study of its poziotinib candidate treatment for non-small cell lung cancer resulted in a preliminary confirmed objective response rate and potential progression - free survival benefit in patients with the EGFR Exon 20 Mutant form of the disease.

«Although still only in an early phase trial, brigatinib is showing an objective response rate in approximately 70 percent of ALK - positive patients post-crizotinib and it's showing about a year of progression - free survival.

The objective response rate (defined as the proportion of complete response and partial responses among all evaluable patients) was also higher with chemotherapy (92/549, 16.8 percent) compared with TKI (39/540, 7.2 percent).

In addition to helping patients live longer, more patients treated with pembrolizumab responded to treatment and for a longer duration than those treated with chemotherapy; the objective response rate — the percentage of patients whose tumours shrank or disappeared — was almost twice as high with pembrolizumab: 21 % compared to 11 % on chemotherapy.

Previously, nivolumab plus ipilimumab had improved progression - free survival (PFS) and objective response rate (ORR) vs ipilimumab alone in the phase II CheckMate 069 and phase III CheckMate 067 trials of treatment - naive patients with advanced melanoma.

Interim phase II results [12] of first treatment with electroporation of IL - 12 in 28 patients with advanced melanoma, after 24 weeks of treatment, reported at the American Society of Clinical Oncology 2014 Annual Meeting, revealed a 32.2 % objective response rate (ORR; the primary endpoint), with a CR in 10.7 %.

Of the 16 evaluable patients, 9 achieved an objective response (56.3 %) and the disease control rate was 68.8 %.

Also, we used objective approaches to quantify neighbourhood attributes that allowed us to partially control for potential reverse causality due to depressed individuals tending to exhibit negative cognitive bias resulting in negative thoughts and perceptions.65 Residential self - selection bias is likely to be a trivial source of reverse causality in this study because Hong Kong's high levels of population density (6760 people / km2) and low percentage of developed land (less than 25 %) 66 limit most residents» choice of accommodation and 37 % of Hong Kong older adults live in public rental housing.67 Given the satisfactory response rate and the level of similarity in depressive symptoms and sociodemographic characteristics of participants recruited from two types of recruitment centres, the findings from this study are likely to be generalisable to the population of Chinese Hong Kong older adults matching the study eligibility criteria and other populations of older adults living in similar ultra-dense metropolises of Southeast Asia.

The ratings rely on objective aspects of experience rather than the individual's subjective attitudes or emotional responses.