Sentences with phrase «observed in different cell»

She adds that it is also unclear why distinct patterns of these sites are observed in different cell types and under different drug treatments.

Not exact matches

In the future, this model will be used to assess whether the clinical heterogeneity observed in breast cancers arises from their different cancer cell of origiIn the future, this model will be used to assess whether the clinical heterogeneity observed in breast cancers arises from their different cancer cell of origiin breast cancers arises from their different cancer cell of origin.

But in many cell lines and patient samples that developed resistance to the combination therapy, the researchers observed something different happening.

Roughly speaking, ChIP sequencing can be compared to a microscope, which enables us to observe the presence of different cell components in the entire genome at a given time.

Given their similar profiles, Seyedsayamdost and coworkers hypothesized that TDA might exhibit anticancer properties as well, and indeed observed its strong anticancer activity in a screen against 60 different cancer cell lines.

But then he observed the same halt in cell division in other cultures with different fetal tissues.

«As the roots of Arabidopsis thaliana contain cells at various phases, it was possible to observe different phases, shown in green and red,» explains Ueda.

Professor Wolf Reik, Head of the Epigenetics research programme, said: «Charting the different developmental timings in the early reprogramming events observed in the human and mouse - derived cells gives the first mechanistic insight into how these events are regulated which is tremendously exciting.

Not only does this let them build up complex tissue components like the mammary gland, but also to experiment with specifically adding in a single cell with a known cancer mutation to different parts of the organoid to observe its effects.

The Nature Communications paper covers lung cancer cells; a similar phenomenon of collective invasion led by distinctive cells has been observed in breast cancer, but different genes and biochemical pathways appear to be important in each system.

The notable differences in fluorescence intensity observed between normal cells and cancer cells, as well as different cancer types, provide important points of differentiation between different cell types and make these probes promising tools for cancer detection and diagnostics.

Instead, we observed cells of a different kind, that are anti-inflammatory, which we believe could be significant in accelerating healing,» explains Lucas Kumosa.

Researchers observed that the immune cells, called CD4 T - cells, in the airways of severe asthmatics secreted different inflammatory proteins than those in mild disease, particularly interferon gamma.

As the authors also observed in previous works, some aphids showed different chromosome numbers also comparing cells belonging to a same individual «forgetting» that chromosome instability within individuals should be typical of malignant cells and not of healthy insects showing a high reproductive rate.

In the new study, the researchers explored the role of cell shape in two vastly different types of epithelial cells — human bronchial epithelial cells grown in the lab and cells within the living embryo of the fruit fly — and observed them as they matured over timIn the new study, the researchers explored the role of cell shape in two vastly different types of epithelial cells — human bronchial epithelial cells grown in the lab and cells within the living embryo of the fruit fly — and observed them as they matured over timin two vastly different types of epithelial cells — human bronchial epithelial cells grown in the lab and cells within the living embryo of the fruit fly — and observed them as they matured over timin the lab and cells within the living embryo of the fruit fly — and observed them as they matured over time.

Such a mechanism could be akin to that observed in the comb jelly (Beroe ovata), where the female pronucleus moves among the different sperm cells before combining with one.

«We were able to observe that the initial assembly of both MTs and F - actin are disrupted upon fertilization of the egg cell, and the growing zygote gradually aligns these fibers in a different pattern from those in the egg cell.

In contrast, no difference was observed in the sensitivity of these cell lines to cytosine arabinoside (ARA - C), a standard chemo - therapeutic drug which targets different pathways (data not shownIn contrast, no difference was observed in the sensitivity of these cell lines to cytosine arabinoside (ARA - C), a standard chemo - therapeutic drug which targets different pathways (data not shownin the sensitivity of these cell lines to cytosine arabinoside (ARA - C), a standard chemo - therapeutic drug which targets different pathways (data not shown).

It is important to distinguish lineage specific gene expression shown here, which occurs at a high level and with a degree of specificity in the different population compartments, to the low level of genome wide transcription observed in ES cells by others [22], or with transcript initiation at many loci noted previously in ES cells [23].

Morphologically similar endothelial cells have been observed when they were differentiated into mature endothelial (CD133 --RRB- by culturing them in high density culture from low density culture at different passages.

They observe that different regions of the gut are more susceptible to tumorigenesis upon inhibition of Notch signalling, suggesting regional differences in stem cell behavior.

Year 4 Science Assessments Objectives covered: Recognise that living things can be grouped in a variety of ways Explore and use classification keys to help group, identify and name a variety of living things in their local and wider environment Recognise that environments can change and that this can sometimes pose dangers to living things Describe the simple functions of the basic parts of the digestive system in humans Identify the different types of teeth in humans and their simple functions Construct and interpret a variety of food chains, identifying producers, predators and prey Compare and group materials together, according to whether they are solids, liquids or gases Observe that some materials change state when they are heated or cooled, and measure or research the temperature at which this happens in degrees Celsius (°C) Identify the part played by evaporation and condensation in the water cycle and associate the rate of evaporation with temperature Identify how sounds are made, associating some of them with something vibrating Recognise that vibrations from sounds travel through a medium to the ear Find patterns between the pitch of a sound and features of the object that produced it Find patterns between the volume of a sound and the strength of the vibrations that produced it Recognise that sounds get fainter as the distance from the sound source increases Identify common appliances that run on electricity Construct a simple series electrical circuit, identifying and naming its basic parts, including cells, wires, bulbs, switches and buzzers Identify whether or not a lamp will light in a simple series circuit, based on whether or not the lamp is part of a complete loop with a battery Recognise that a switch opens and closes a circuit and associate this with whether or not a lamp lights in a simple series circuit Recognise some common conductors and insulators, and associate metals with being good conductors