Sentences with phrase «observed in embryonic stem cells»

Initial analysis found a significant enrichment of PRC1 / 2 targets in hypermethylated promoters in bCSCs, similar to that observed in embryonic stem cells (ESCs)[2].

Yamanaka's group and two others followed up earlier this year with firmer evidence that these induced pluripotent stem (iPS) cells faithfully mimicked the patterns of gene activity and cellular differentiation observed in embryonic stem cells.

Not exact matches

One caveat is that the authors also observed that one of the eight human embryonic stem cell lines established following spindle transfer showed a drift in mitochondrial heteroplasmy in a subset of stem cells, despite low levels of carryover detected in the embryo.

AST - OPC1, an oligodendrocyte progenitor cell population derived from human embryonic stem cells, has been shown in preclinical testing in animals and in vitro to have three potentially reparative functions that address the complex pathologies observed in demyelination disorders, such as spinal cord injuries, and multiple neurodegenerative diseases, including multiple sclerosis and white matter stroke.

Following this, they demonstrated that neural progenitors from embryonic stem cells could differentiate themselves into neurons in rat brains presenting lesions similar to those observed in humans.