Estimates of current and ancestral population sizes (Ne1 = 1,600,000; Ne2 = 780,000; Nancestral = 470,000), divergence time (1,800,000 years and assuming a generation time of 1 year), and gene flow (2Nm1autosomal = 1.69; 2Nm2autosomal = 0.83; 2Nm1X - chromosome = 0.38; 2Nm2X - chromosome = 0.26) were
obtained from previous studies and inferred using an Isolation - with - Migration model [21], [26].
GWAS data from 10 randomly selected English bulldogs and Standard Poodles was
obtained from previous studies [23, 29].
Not exact matches
«The radiation dose rates
from measurements
obtained over the last four years exceeded trends
from previous solar cycles by at least 30 percent, showing that the radiation environment is getting far more intense,» said Nathan Schwadron, professor of physics and lead author of the
study.
Previous genetic
studies have examined the association of aspirin, NSAIDs, or both with colorectal cancer according to a limited number of candidate genes or pathways.6 - 10 Thus, to comprehensively identify common genetic markers that characterize individuals who may
obtain differential benefit
from aspirin and NSAIDs, we conducted a discovery - based, genome - wide analysis of gene × environment interactions between regular use of aspirin, NSAIDs, or both and single - nucleotide polymorphisms (SNPs) in relation to risk of colorectal cancer.
With the exception of IK14 (0.1 — 0.26 μg / mL), the values
obtained (0.98 — 1.87 μg / mL) were above or consistent with expected trough values derived
from our
previous pharmacokinetic
study [38].
The mitral regurgitation area (MRA), vena contracta (VC) diameter and regurgitant fraction of proximal isovelocity surface area (RF PISA) were
obtained from color flow mapping (Doppler)
from the left apical four - chamber view, as described by
previous studies (Kittleson and Brown, 2003; Muzzi et al., 2003; Gouni et al., 2007).
Reported alpha for the IBI scale ranged
from.94 to.98 in
previous studies (Dweck, et al., 1995), and an alpha of.89 was
obtained for the current
study.
In a
previous validation
study of the SDQ [43] data were
obtained from 263 randomly selected parents of children 5 — 15 years old in the general population, but the authors did not present the norms in detail besides a figure presenting mean value of the Total Difficulties score of SDQ and subscales for the entire sample.
However, correlations between the FIMP scores and outcome measures found in our
study are not lower than those reported in
previous studies in which FIMP scores were
obtained from the same families as the outcome variables (see Forgatch and DeGarmo 2011; Hukkelberg and Ogden 2013).