It has been proposed that the volume mismatch between the CCF and brain parenchyma in CKCS can be explained by impaired
occipital bone development and the consequent reduction in CCF volume [5], [16], [21].
The authors suggested that, in this breed,
occipital bone development is insensitive to changes in hindbrain volume and that there is a compensatory bulging of the tentorium cerebelli in a rostral direction [39].
Not exact matches
If this is also true in dogs it may have implications for the
development of CM, as the CCF may have a restricted capacity to adapt to the volume of an enlarged cerebellum through expansion of the sutures between the
occipital bones and their neighbours.
Although the
occipital bone comprises a single bony plate in an adult individual, its
development is complex and mosaic as it develops from the basioccipital, exoccipital, and supraoccipital
bones which are derived from distinct acrochordal and parachordal,
occipital arch, and supraoccipital cartilages, respectively [40].