Sentences with phrase «occur from time to time which»

Many commonplaces of today are the improbabilities of yesterday, and in any branch of science «improbabilities» occur from time to time which are apparently arbitrary exceptions to previously observed rules.

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

Forward Looking Statements This press release may be deemed to contain forward - looking statements, which are subject to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, including the expected completion of the acquisition, the time frame in which this will occur, the expected benefits to Facebook and WhatsApp from completing the acquisition, and the expected financial performance of Facebook following completion of the acquisition.

The market's 10 % correction in early February - which we believe was simply a healthy release of market excesses - serves as a good reminder to investors that corrections do occur from time to time.

The fossil record which shows millions of years of stable species, then an explosion of necessarily mutations, all occurring at the precise necessary time required for complex organisms to develop, and ALL escaping fossilization «the sudden appearance of most species in the geologic record and the lack of evidence of substantial gradual change in most species — from their initial appearance until their extinction — has long been noted, including by Charles Darwin who appealed to the imperfection of the record as the favored explanation» — Wikipedia

But why the changes should occur at alland at the time that they do and why they should advantageously adapt the organisms to their environment and not produce monstrosities so different from their environmentally adapted parents, monstrosities which would normally be condemned to a quick extinction, that is a mystery.

But why the changes should occur at all and at the time that they do and why they should advantageously adapt the organisms to their environment and not produce monstrosities so different from their environmentally adapted parents, monstrosities which would normally be condemned to a quick extinction, that is a mystery.

For the first time historical events appeared as radically particular, as confined in their meaning and value to the actual but singular process in which they occur, and thus as being wholly detached from a universal order or law.27

(From the Christian point of view (which in this coincides with the biological viewpoint logically carried to its extreme) the «gathering together» of the Spirit gradually accomplished in the course of the «coiling» of the Universe, occurs in two tempos and by two stages — a by slow «evaporation» (individual deaths); and simultaneously b by incorporation in the collective human organism («the mystic body») whose maturation will only be complete at the end of Time, through the Parousia.)

Even though the mind has a certain kind of power over the biological subsidiaries in which it dwells, it is at the same time susceptible to suffering from modifications that occur within its substrata.

Turmeric powder is very safe to consume but side effects can occur when very high quantities are consumed over a long duration of time continuously — and can be from supplements which have been manipulated by technology with the turmeric no longer in its natural form.

The fermentation process that occurs in a batch of kombucha results in traces of alcohol which can vary in levels from drink to drink and over time.

In a paper published in the journal Behavioral Sciences and the Law, scientists at the University of Colorado School Medicine note that, all too often, the «sensational media attention» surrounding CTE «divorce discussion of CTE from the well - established natural history and typically favorable prognosis of mTBI,» while, at the same time, such reports - and the scientific reports about CTE to which they are connected - imply direct connections between complex, multi-determined behaviors such as murder and / or suicide and mTBIs occurring in the remote past of individuals engaging in those behaviors.»

One way, I believe, to address the problem of under - reporting and increase the chances a concussion will be identified early on the sports sideline may be to rely less on athletes themselves to remove themselves from games or practices by reporting concussion symptoms (which the most recent study shows occurs at a shockingly low rate, [9] or on game officials and sideline observers to observe signs of concussion and call for a concussion assessment, but to employ technology to increase the chances that a concussion will be identified by employing impact sensors designed to monitor head impact exposure in terms of the force of hits (both linear and rotational), number, location, and cumulative impact, in real time at all levels of football, and in other helmeted and non-helmeted contact and collision sports, where practical, to help identify high - risk impacts and alert medical personnel on the sideline so they can consider performing a concussion assessment.

According to the New York Times, «Organic farmers can lose sales if genetic engineering is detected in their crops, which occurs through cross-pollination from a nearby field or through intermingling of seeds.

For immigration from outside the EU, the UK government could, at any time, enact a law to change the basis on which that immigration occurs.

At the same time, DeFrancisco is pushing legislation that would give patients the ability to bring medical malpractice cases beginning from when they discover the error, not from when the mistake occurred, which is current law.

In both Einstein's and Ellis» pictures, the time at which each person perceives both events to have occurred is based on the discrepancies between how long it takes light from each event to reach them.

However, AAAS will not be liable for damages or refunds should the site become unavailable temporarily or access to the site becomes slow or incomplete due to system back - up procedures, regular maintenance (which typically occurs 8 - 10 am Pacific time each Saturday), Internet traffic volume, upgrades, overload of requests to the servers, general network failures or delays, or any other cause beyond the control of AAAS (including, but not limited to, force majeure events, networking problems, IP address changes) which may from time to time make the site inaccessible for Authorized Users.

On top of that, explorations occurred during a time of global cooling known as the Little Ice Age, which stretched from the 13th to early 20th centuries.

yes IED's do have shrapnel but I believe the biggest threat is from the superhot liquid metal, IE they put copper shavings or something along those lines in the device so when the explosion occurs a jet of liquid metal is projected in a directed fashion (in the most deadly IED's) so as to either burn thru soft barriers and to weaken hardened materials which the following shrapel has an easier time penetrating.

The new RSS v4 TLT record makes a number of changes to the time of observation correction, as well as corrections for the change in instruments that measure temperature from microwave sounding units (MSU) to advanced microwave sounding units (AMSU) sensors, which occurred around the year 2000.

Located in an area that has ruptured six times since 1857, the hole provided the first opportunity to observe directly the conditions under which earthquakes occur, to collect rocks and fluids from the fault zone for laboratory study, and to continuously monitor the physical condition within an active earthquake nucleation zone.

In addition to disputing the relevance of your source trial (which doesn't appear to offer a duration or suggestion that the tests increase healthy lifespan of the mice in question), I'd like to point out that protection is less beneficial in the long term, because you can not stop damage from occurring completely no matter how well you defend an organelle, and that damage will accumulate over time.

In pointing out the significance of the above findings, it is important to note that, over a period of time in which the bulk of the modern rise in atmospheric CO2 has occurred, not only have the majority of glaciers from this large region of Antarctica not retreated, they have collectively grown!

Instead of David being simply turned on by all the naked flesh, the respectable facility's grouchy and annoyed owner (Ho Young Chung) asks his young employee to police the upstairs rooms, where illegal gay makeout sessions seem to occur from time to time, putting David in the supremely awkward position of having to look for what he secretly craves so he can put a premature end to it, which thus subliminally suggests some of his inner struggle.

With each area being cordoned off from the rest of the stages, the pacing can feel a little off at times, with environmental transitions happening suddenly after a loading screen rather than dynamically occurring as in the Souls games, but this more concentrated focus on the levels also allows for condensed, goal based gameplay that is almost impossible to achieve in Dark Souls, which is certainly welcomed when you're short on time and just want to grind out a twilight mission or two.

The overlong running time - coupled with Douglas» inability to move things along at a brisk clip - effectively drains the tension from some of the movie's more outwardly suspenseful moments (ie Braden's mission, which occupies much of the third act, seems to occur in real - time, which certainly dilutes its impact), ensuring that Up Periscope remains strangely uninvolving throughout its 111 minutes.

To provide your students with more information about the time and places in which the Holocaust occurred, have them read appropriate context for the stories the survivors will share from Facing History and Ourselves: Holocaust and Human Behavior.

Note that there are also capital gains distributions, which are typically distributed to help offset capital gains taxes that may occur from time to time with an ETF.

Gastrointestinal stasis, which occurs when food fails to empty from the stomach and cecum, can be fatal if it goes on for a long period of time.

There are two types of dog epilepsy — primary and secondary — in which seizures can occur from several times a day to once in a blue moon.

In Buenos Aires, every time you buy a drink at the bar you must first order from one of the cashiers seated at the end of the bar, who then writes out your order on a receipt which you must then hand to the bartender (which seems overly bureaucratic, especially on those occasions when I had to complete this process even when the bartender was simply standing next to the cashier waiting for the transaction and exchange of receipts to occur).

during SP mission Nightshift • Fixed issue with last mission not listed in REPLAY MISSIONS list • Fixed issue on the SP mission Night Shift where three of the marines that repel down from the Osprey at the start of the level have PLR models instead of the right marine models • Has been made harder to fail missions due to zero tolerance friendly fire • Fixed MG nest objective on Operation Guillotine • Fix for music climax on mission «Fear No Evil» • Fixed issues that occurred if user were backtracking after fight at elevator on SP mission «Comrades» • Adding a back button to SP campaign select difficulty screen • Removed slomo from jump into train on SP mission «The Great Destroyer» • Fixed glitches in subway Quick Time Events in mission «The Great Destroyer» • Increased quality of the loading screen images • Fixed glitch that made it possible to reach Solomon train QTE with the wrong weapon equipped in mission «Semper Fidelis» • Fixed final sound fade out on SP mission «Thunder Run» • Removed sound fade on convoy ride in mission «Operation Guillotine» • Fixed squad mates coming through wall after intro on SP mission «Operation Guillotine» • SP mission, «The Great Destroyer»: moved Campaign Cleared achievement until after the Dima outro • Fixed soldiers inside of terrain at start of level in «OPERATION GUILLOTINE» • SP mission, «The Great Destroyer»: Fixed streaming issue which could lead to out of memory when streaming in Subway ride • Improved music and music fade on tank encounter in mission «Operation Guillotine» • Sound on Operation Guillotine: Fixed trading floor crash camera shake and rumble • Fade later when driving in to tunnel on «OPERATION GUILLOTINE» • Hide cross hair during Solomon intro & climb out scene on «Operation Swordbreaker» • Fixes on «OPERATION SWORDBREAKER»: Skip VO urging the player to move forward if the player has already moved.

The graphical style which dates from 1994, displayed in the Game Boy's small resolution, means that managing a 100 - floor building can get very busy and at times it's difficult to spot problems as they occur.

- the team has been adding weapons one by one because they want the same amount of attention for each weapon - the team learned that when they added two new weapons at once, one would end up getting overshadowed by the other - there were more new stages than returning stages because bringing back old stages would have little surprise - since they want to satisfy both new and returning players, they changed the order of stage additions - there weren't any major direction changes in balancing from Splatoon 1 - there have been more pattern combinations between weapons and stages, so there was more involved to balance them all - matchmaking is handled by getting 8 players with similar rank points, and then they're split by weapons - the rank point gap between S + players is bigger than ordinary players - only about one in 1,000 active players are in the S +40 to S +50 region in Ranked Battles - there's even less than one in 10 players that reach S +, while 80 % of the overall player base are in A or less - about 90 % of S + ranked players are within a + / -150 hidden ranked power range - rock was the popular genre in Splatoon, so they tried changing it for the sequel - they prioritized making good background music first before forming the band to play that music - the design team would make the CD jacket - like artwork afterwards - due to this, the band members would often change; some getting added while some others removed - Off the Hook is an exception, as they first decided they would be a DJ and rapper along with their visuals first - Off the Hook's song came afterwards - In Splatoon street fashion was the trend, but in Splatoon 2 they tried adding more uniqueness - the aim was to add Flow with ethnic clothing and Jelfonzo with high fashion - all Jellyfish in this world are born by splitting, which means Jelfonzo was born by splitting from Jelonzo - Jellyfish are like a hive mind - when they hold a wedding ceremony, they're just simply holding the ceremony - Jelonzo and Jelfonzo start gaining their own consciences so they can speak - Flow used her working holiday to go on a trip before reaching Inkopolis Square - during the trip, she met the owner of Headspace - the owner liked her, so she got hired to work there - Bisk has a unique way of speaking: anastrophe - the team tried to express him as an adult man - they made him into a giant spider crab because they wanted someone with high posture - he came from a cold country and broke up with his girlfriend to join a band - just like Flow, he became attracted to squids - Crusty Sean finally has his own shop, but he opened it because he's someone who follows the current trends - one of the trends happens to be people opening their own shops - drink tickets aren't stacked, but the probability is higher than a single brand - the music in Inkopolis Square changes depending on the player's location - sounds contribute to creating atmosphere in the location - the song at front of Grizzco Industries had an atmosphere that feels like some smell can radiate from the game screen - as for Salmon Run, they imagined it as a Japanese restaurant outside Japan that is not run by a Japanese person - each time the player moves between the shops, the game uses an arrange shift that shows the personality of each inhabitant - the arrangement in Shella Fresh is related to Bisk's guitar and mystery files that describe his past - with the Squid Sisters moved to Hero Mode, Off the Hook was put in charge in guiding battles and festivals - Bomb Rush Blush has an orchestra «because it would sound like the final boss» - the team wanted to express the feel of the story's real culprit with this music - the probability of each event occurring in Salmon Run is different - there are no specific requirements, meaning they're picked randomly - this means it's possible for fog to appear three times in a row - the Salmon have different appearances based on the environment they're raised in - if the environment is harsher, they would become large salmon - Steelheads and Maws have big bodies, while Scrappers and Steel Eels have high intelligence - Salmons basically wield kitchenware, but everybody else has a virtue in fighting to actually cook the Salmons - Grill is the ultimate form of this - when Salmons are fighting to the death, they can feel the same sense of unity - they would be one with the world if they were eaten by other creatures, and they also fight for the pride of their race - MakoMart is based on a large supermarket in America - the update also took place on Black Friday in America, which was why Squids are buying a lot of things in the trailer - Arowana Mall looks like it has more passages because there are changes in tenants and also renovation work - Walleye Warehouse has no changes at all, because the team wanted to have at least one map that stayed intact - the only thing different in this map is the graffiti, which is based on the winner of Famitsu's Squid Fashion Contest - all members in the band Ink Theory graduated from music university - they are well - educated girls who also do aggressive things - the band members wearing neckties are respecting the Hightide Era from the prequel - the team will continue adding weapons and stages for a year, and Splatfests for two years - the team will also continue to make more updates including balancing

In addition, a lack of evolution for Mario also hinders the experience, from battles you only get an advancement to the amount of paint you can carry which is handy in both battles and the overworld, but there is no expansion to Mario and his strength from battles which often made them pointless to fight and feel like you are wasting time whenever they occur.

If your opponent fails to move out of it, or fails to interrupt you, then a short real - time special move occurs, which can range from a flurry of sword stabs to an attack from an orbital laser.

New downward headers, low driven shots (which were done by hitting square once to shoot and then again as you're about to connect with the ball) and through balls that can now be hit with power that uses the same «Passing With Purpose» system that was introduced previously worked well without any problems occurring from my time with the game.

Apichatpong Weerasethakul, as one of the most original filmmakers and artists of our time, has developed a distinctive language which approaches fragments of life, from passing gestures to the great cycles, from the often occurring to the unseen, in arresting and compelling narratives.

The gallery's collection is an invaluable reflection of movements and initiatives that have occurred from the time of the Impressionists to today including superb works acquired from the ROSC series of exhibitions which occurred between 1967 and 1988.

Here's a quick roundup from my Twitter output, which fills in the gaps between Dot Earth posts when notable developments occur but I don't have time to write here.

Starting from an old equilbrium, a change in radiative forcing results in a radiative imbalance, which results in energy accumulation or depletion, which causes a temperature response that approahes equilibrium when the remaining imbalance approaches zero — thus the equilibrium climatic response, in the global - time average (for a time period long enough to characterize the climatic state, including externally imposed cycles (day, year) and internal variability), causes an opposite change in radiative fluxes (via Planck function)(plus convective fluxes, etc, where they occur) equal in magnitude to the sum of the (externally) imposed forcing plus any «forcings» caused by non-Planck feedbacks (in particular, climate - dependent changes in optical properties, + etc.).)

Also at New York Times (though what to make of «scientists said the ice sheet was not melting because of warmer air temperatures, but rather because of the relatively warm water, which is naturally occurring, from the ocean depths»...?)

Desler, Alexander, and Timlin (1996) said: «A prominent decade - long perturbation in climate occurred during the time period [1970 — 1991] in which surface waters cooled by 1 °C in the central and western North Pacific and warmed by about the same amount along the west coast of North America from late 1976 to 1988.»

It would have to be shown that the recent temperature record can be statistically significantly distinguished from the statistically significant warming signal, which can be detected when performing an analysis that uses data over multiple decades, from the mid-1970ies to present, or from the mid-1970ies up to the time, when the alleged change in the behavior of the global atmospheric temperature is supposed to have occurred.

It has been established experimentally that, at ca 4.0 ka BP, there occurred a global change in the structure of atmospheric circulation, which coincided in time with the discharge of glacial masses from Greenland to North Atlantic and a solar activity minimum.

-- The Secretary of the Treasury shall transfer from time to time to the Trust Fund, from amounts in the general fund of the Treasury that are not otherwise appropriated, such sums as the Chief Actuary of the Centers for Medicare & Medicaid Services calculates as necessary (and so certifies to such Secretary) for any fiscal year, on account of changes in benefit costs and changes in tax revenue attributable to the provisions of the American Clean Energy and Security Act of 2009 and the amendments made thereby, in order to place the Trust Fund in the same position at the end of such fiscal year as the position in which it would have been if such changes had not occurred.».

''... worked with two sediment cores they extracted from the seabed of the eastern Norwegian Sea, developing a 1000 - year proxy temperature record «based on measurements of δ18O in Neogloboquadrina pachyderma, a planktonic foraminifer that calcifies at relatively shallow depths within the Atlantic waters of the eastern Norwegian Sea during late summer,» which they compared with the temporal histories of various proxies of concomitant solar activity... This work revealed, as the seven scientists describe it, that «the lowest isotope values (highest temperatures) of the last millennium are seen ~ 1100 - 1300 A.D., during the Medieval Climate Anomaly, and again after ~ 1950 A.D.» In between these two warm intervals, of course, were the colder temperatures of the Little Ice Age, when oscillatory thermal minima occurred at the times of the Dalton, Maunder, Sporer and Wolf solar minima, such that the δ18O proxy record of near - surface water temperature was found to be «robustly and near - synchronously correlated with various proxies of solar variability spanning the last millennium,» with decade - to century - scale temperature variability of 1 to 2 °C magnitude.»

Led by Dr. James E. Hansen from 1981 to 2013, research at GISS emphasized a broad study of global change, which is an interdisciplinary initiative addressing natural and man - made changes in our environment that occur on various time scales — from one - time forcings such as volcanic explosions, to seasonal / annual effects such as El Niño, and on up to the millennia of ice ages — and that affect the habitability of our planet.