Sentences with phrase «occurring gain of function»
The variant is a naturally occurring gain of function mutation that has been shown to have 8 to 12 times greater activity levels than the wildtype gene.
http://www.frontlinegenomics.com/ Not exact matches
Dovat's team set out to gain a better understanding of how impairments in Ikaros function occur in B - ALL, which they hoped could help them develop a drug to target and improve the protein's activity.
The main hormone that supports muscle building is testosterone, which is a naturally occurring hormone in your body that has lots of important functions in your body, including muscle growth, minimizing fat gain, increasing strength and giving you more energy among others.
Lack of ovulation, whether it occurs naturally as the result of aging ovaries, or unnaturally, from extremes of stress, exercise, diet, and / or use of synthetic hormones in HRT or birth control pills, will cause estrogen to drop from 40 to 60 percent (enough to stop the menstrual cycle), but progesterone levels plummet much lower, to nearly zero in some women causing a raft of symptoms from heavy / painful periods, mood swings, PMS and depression to water retention, weight gain, slowed thyroid function, and heightened risks for endometriosis, fibroids, fibrocystic breasts as well as breast and uterine cancer.