Sentences with word «octamer»

Center cells lost the expression of octamer - binding transcription factor 4 (OCT4) and epithelial cadherin (E-cadherin) faster than perimeter cells, which are critical to the development of heart tissue.
A new technique of direct binding of radioactive DNA was used to screen a complementary DNA expression library from the BJAB cell line in lambda gt11 phage to derive molecular cDNA clones representing a putative B lymphocyte - specific octamer binding protein.
Cloning of a lymphoid - specific cDNA encoding a protein binding the regulatory octamer DNA motif
Repression of the IgH enhancer in teratocarcinoma cells associated with a novel octamer factor
The fusion protein produced on inducing a lysogen of one phage bound to a monomeric octamer probe.
Intriguingly, in contrast to the canonical nucleosome (where 147 bp of DNA are wrapped around the histone octamer), only the central 121 bp were visible, suggesting flexible CENP - A nucleosomal ends.
VP40 is a transformer protein, capable of rearranging itself into different structures: monomer, dimer and octamer.
The dimer is best equipped to facilitate replication, performing twice as well as the monomer, and nearly 10 times better than the octamer.
Alterations of the octamer motif increased enhancer activity.
Most of the affected residues are in four clusters, in sequences homologous to the octamer 5 «CAGGTGGC 3» (C, cytosine; A, adenine; G. guanine; T, thymine).
It is proposed that NF - A3 represses specific regulatory sequences that contain the octamer motif.
Nuclear extracts from F9 cells contained an octamer binding protein (NF - A3) that was unique to EC cells; the amount of NF - A3 decreased upon differentiation.
An octamer DNA sequence plays a critical role in directing transcription of immunoglobulin genes in B lymphocytes.
Thus, this cDNA derives from a gene (oct - 2) that specifies an octamer binding protein expressed preferentially in B lymphocytes, proving that, for at least one gene, a cell - specific transcription factor exists and its amount is controlled through messenger RNA availability.
The plaques were screened with DNA containing four copies of the octamer sequence and positive phage recombinants were identified.
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