Sentences with phrase «octamer binding»

A new technique of direct binding of radioactive DNA was used to screen a complementary DNA expression library from the BJAB cell line in lambda gt11 phage to derive molecular cDNA clones representing a putative B lymphocyte - specific octamer binding protein.

Thus, this cDNA derives from a gene (oct - 2) that specifies an octamer binding protein expressed preferentially in B lymphocytes, proving that, for at least one gene, a cell - specific transcription factor exists and its amount is controlled through messenger RNA availability.

Not exact matches

The fusion protein produced on inducing a lysogen of one phage bound to a monomeric octamer probe.

Cloning of a lymphoid - specific cDNA encoding a protein binding the regulatory octamer DNA motif

Center cells lost the expression of octamer - binding transcription factor 4 (OCT4) and epithelial cadherin (E-cadherin) faster than perimeter cells, which are critical to the development of heart tissue.

Oct4 contains two distinct DNA binding domains (the POUH and POUS domains, each of which can bind to half of the DNA octamer motif independently of the other) which are separated by a flexible linker [39]; this in turn allows for substantial leeway in arrangement of these domains in relation to each other [17].

Oct4 has two distinct DNA binding domains which independently bind half - sites of the canonical octamer motif.