In order to establish the physicochemical properties of the most efficient bioadhesive polymers to be used as
ocular inserts in order to administer said antibiotic, during research, the CEU UCH team has performed moxifloxacin diffusion ex vivo experiments through rabbit corneas preserved at different temperatures.
Researchers from Valencia's UCH CEU University have developed
ocular inserts which allow a patient's cornea to absorb more antibiotics than current methods.
Therefore, pharmaceutical research aims to develop
ocular inserts, very thin cylinders or discs made of bioadhesive polymeric materials, which adapt to the shape of the eye and release the medicine through the cornea in a controlled manner.»
In the study, 64 patients received the topical
ocular insert containing the glaucoma drug bimatoprost.
The development of
this ocular insert to administer moxifloxacin opens new treatment possibilities for ocular infections.
Researchers at the Pharmacy Department of the CEU Cardenal Herrera University have published the design of a new bioadhesive
ocular insert which is placed inside the eyelid and releases a larger amount of medicine through the cornea in a controlled way in the international journal Drug Delivery and Translational Research.
Not exact matches
Specifically, researchers at the CEU UCH have developed this new
insert for the
ocular administration of the antibiotic moxifloxacin, which is applied in cases of bacterial infections of the eyes such as corneal queratitis or bacterial endophthalmitis.
The research has made it possible to develop a very thin, practically transparent
insert which is easily adhered to the
ocular mucosa, providing larger concentrations of moxifloxacin through the cornea than other administration formats currently commercialised, such as orally.
According to the CEU UCH research team, «the
ocular release of moxifloxacin with this
insert would make for an improved treatment of some
ocular illnesses such as bacterial endophthalmitis, an infection of the eyeball which can appear after suffering a wound or as a complication following intraocular surgery.
Regardless of whether an artificial lens is
inserted, your pet will not be able to adjust the
ocular focal point and will see best when objects are 10 - 20 feet away.