«Spatial perception of
odorants in cockroaches.»
For the first time is has been demonstrated that measurements of
odorants in the air may be an alternative to dynamic olfactometry that can be applied for measuring odour from pig houses and the effects of odour abatement technologies.
«New method for exhaustively isolating olfactory receptors responding to specific odorants: Step toward the elucidation of a mechanism for recognizing
odorants in mammals.»
Using the Single - Cell Automatic Analysis and Isolation System developed in 2013, this group isolated single OSNs responding to specific
odorants in a time - lapse single - cell - array cytometric manner and identified the OR gene through single cell polymerase chain reaction (PCR).
Usually, it takes a nose to smell, but now — for the first time — scientists have developed a convincing model able to measure odours from pig farms by means of precise measurements of the content of
odorants in the atmosphere.
The scientists also aimed to identify significant
odorants in order to assess odour emission from the pig facilities as well as the effect of technologies that reduce odour problems.
Both methods have advantages and disadvantages, but the optimum method would be to be able to quantify the connection between the smell that the human nose experiences and the actual, measured amount of specific
odorants in the air.
Not exact matches
Turin says the strongest tests of his theory so far come from studies
in which researchers replace an
odorant atom with an isotope of that atom, which has a slightly different weight and changes the molecule's frequency of vibration.
The group calculated that an electron could «tunnel» through the barrier imposed by the
odorant, an effect made possible by quantum mechanics, they wrote
in a preprint accepted for publication
in Physical Review Letters.
Turin's more controversial theory, put forth
in 1996 and now the subject of two popular books, holds instead that
odorant receptors sense the way a molecule's atoms jiggle.
A study published
in 2004
in Nature Neuroscience, for example, found that people could not discriminate between two such
odorants.
«But
in fact, there are many more than 128
odorants, and so the actual number will be much, much bigger.»
In the case of β - ionone, the smell associated with violets, McRae and colleagues managed to pinpoint the exact mutation (a change in the DNA sequence) in the odorant receptor gene OR5A1 that underlies the sensitivity to smell the compound and to perceive it as a floral note — people who are less good at smelling β - ionone also describe the smell differently, as sour or pungent, and are less likely to find it pleasan
In the case of β - ionone, the smell associated with violets, McRae and colleagues managed to pinpoint the exact mutation (a change
in the DNA sequence) in the odorant receptor gene OR5A1 that underlies the sensitivity to smell the compound and to perceive it as a floral note — people who are less good at smelling β - ionone also describe the smell differently, as sour or pungent, and are less likely to find it pleasan
in the DNA sequence)
in the odorant receptor gene OR5A1 that underlies the sensitivity to smell the compound and to perceive it as a floral note — people who are less good at smelling β - ionone also describe the smell differently, as sour or pungent, and are less likely to find it pleasan
in the
odorant receptor gene OR5A1 that underlies the sensitivity to smell the compound and to perceive it as a floral note — people who are less good at smelling β - ionone also describe the smell differently, as sour or pungent, and are less likely to find it pleasant.
Zwiebel and colleagues scanned the mosquito genome looking for genes similar to those that generate fruit fly
odorant receptors, proteins that project from nerve cells and initiate a biochemical cascade when they encounter certain molecules
in the air.
McRae and colleagues found that the genetic variants associated all lie
in or near genes that encode so - called
odorant or olfactory receptors.
The smells of these four
odorants are familiar, for those who can smell them (though their names may not be): malt (isobutyraldehyde), apple (β - damascenone), blue cheese (2 - heptanone), and β - ionone, which smells floral to some people and is particularly abundant
in violets.
This latest smell prediction effort began with a recent study by olfactory researcher Leslie Vosshall and colleagues at The Rockefeller University
in New York City,
in which 49 volunteers rated the smell of 476 vials of pure
odorants.
The
odorant receptor molecules sit on the surface of sensory nerve cells
in our nose.
In the cardiomyocytes, they activated the OR51E1 receptor with the
odorant nonanoic / decanoic acid, which causes a rancid - fatty olfactory sensation.
The team performed a series of tests, including comparative Aroma Extract Dilution Analysis (AEDA) as well as sensory evaluation by a panel of 10 participants who had received extensive training
in identifying different wine
odorants.
For example, based on the perception of the hundreds of
odorant molecules found
in coffee, the piriform cortex would be able to recognize a single odor, that of coffee.
Paying attention to the fact that each olfactory sensory neuron (OSN) expresses an OR, Shun «ichi Kuroda, Professor and Nobuo Yoshimoto, Specially Appointed Associate Professor at the Department of Biomolecular Science and Reaction, The Institute of Scientific and Industrial Research, Osaka University
in cooperation with Masato Suzuki, Chief Researcher, Advanced Research Division, Panasonic Corporation made a system
in which OSNs from mice were applied to a microchamber array on a microscope slide and fluorescence was yielded when ORs responded to
odorants.
A side effect of losing PRMT - 5
in C. elegans is a heightened sense of smell: In the worms, dopamine signaling acts as a brake or check on the sensory system's response to odorant
in C. elegans is a heightened sense of smell:
In the worms, dopamine signaling acts as a brake or check on the sensory system's response to odorant
In the worms, dopamine signaling acts as a brake or check on the sensory system's response to
odorants.
Christine Mißbach, first author of the study, analyzed the active genes
in the insect antennae where the olfactory receptors are located and describes her discovery this way: «Astonishingly, the firebrat, which is more closely related to flying insects, employs several co-receptors, while the
odorant receptors themselves are absent.»
However, the researchers did not find any evidence for an olfactory system which is based on
odorant receptors
in the most basal insect, the jumping bristletail.
Despite these miniscule variations, the flies showed a consistent preference for one arm of the maze over the other, the team reports online today
in the Proceedings of the National Academy of Sciences, suggesting that the flies could tell the difference between the
odorants.
In 2007 Turin (who is now chief technical officer of the odorant - designing company Flexitral in Chantilly, Virginia) and his hypothesis received support from a paper by four physicists at University College Londo
In 2007 Turin (who is now chief technical officer of the
odorant - designing company Flexitral
in Chantilly, Virginia) and his hypothesis received support from a paper by four physicists at University College Londo
in Chantilly, Virginia) and his hypothesis received support from a paper by four physicists at University College London.
In addition, each foodstuff has its own odor code comprised of a core group of between just 3 and 40 of the 230 key odorants — in specific concentration
In addition, each foodstuff has its own odor code comprised of a core group of between just 3 and 40 of the 230 key
odorants —
in specific concentration
in specific concentrations.
Then, as now, the prevailing notion was that the sensation of different smells is triggered when molecules called
odorants fit into receptors
in our nostrils like three - dimensional puzzle pieces snapping into place.
The findings also lay the scientific groundwork for the next generation of aroma products, which use the potential of optimized biosynthetic pathways
in plants for industrial - scale production of high - quality food
odorants.
The study «A long - range cis - regulatory element for class I
odorant receptor genes» published
in Nature Communications was a collaborative effort between Tokyo Tech, the University of Tokyo, Nihon BioData Corporation and RIKEN Brain Science Institute.
This study demonstrates, for the first time, that the mammary pheromone helps pups learn other
odorants, says neuropsychologist Peter Brunjes of University of Virginia
in Charlottesville.
In one recent study, 17 patients with moderate, persistent asthma took whiffs of a nonirritating
odorant.
Competing interests: The Weizmann Institute has filed a patent on «predicting
odorant pleasantness with an electronic nose» as described
in this manuscript.
Differential Electrophysiological Responses to
Odorant Isotopologues
in Drosophilid Antennae
The blue stars on the upper x axis denote the 7
odorants where native Ethiopians and native Israelis significantly differed
in their pleasantness ratings.
Now that Mainland et al have published «The missense of smell: functional variability
in the human
odorant receptor repertoire» and Foote et al have published «Tracking niche variation over millennial timescales
in sympatric killer whale lineages,» the similarities at the top of the aquatic and terrestrial food chains attest to the power of conserved molecular mechanisms to link cause and effect across all species via olfaction and odor receptors, which is what I detailed
in the review I submitted last week.
Transcriptomic and Proteomic Profiling Revealed High Proportions of
Odorant Binding and Antimicrobial Defense Proteins
in Olfactory Tissues of the House Mouse — Barbora Kuntová — Frontiers
in Genetics
Technical details of these research topics focus on light - induced electron transfer reactions, both at surfaces and
in transition - metal complexes, surface chemistry and photochemistry of semiconductor / liquid interfaces, novel uses of conducting organic polymers and polymer / conductor composites, and development of sensor arrays that use pattern recognition algorithms to identify
odorants, mimicking the mammalian olfaction process.
Important advances have included the discovery of the first evidence that the odour response is governed by neurons, of the intracellular signalling pathways between
odorant receptors and sensory neurons, and of specific neurons, receptors and neurotransmitters involved
in behaviour adaption following experience.
In behavioural experiments, consequences to single animal performance in learning and memorizing odorants will be verifie
In behavioural experiments, consequences to single animal performance
in learning and memorizing odorants will be verifie
in learning and memorizing
odorants will be verified.
in learning and memorizing
odorants will be verified.
The mammalian olfactory system is formed by the olfactory mucosa (OM) and the vomeronasal organ (VNO) and is dedicated to sensing
odorants and pheromones present
in the environment.
In a previous paper (Franco et al. (2011) Proc Natl Acad Sci USA 108:9, 3797 - 802) we showed that fruit flies can recognize the presence of deuterium in odorants by a vibrational mechanis
In a previous paper (Franco et al. (2011) Proc Natl Acad Sci USA 108:9, 3797 - 802) we showed that fruit flies can recognize the presence of deuterium
in odorants by a vibrational mechanis
in odorants by a vibrational mechanism.
Drosophila appears able to recognize the presence of deuterium
in odorant isotopomers by a vibrational mechanism [12].
The scientists tested the response of these mosquitoes to skin
odorants by placing them
in a wind tunnel with a plate of glass beads that had been worn
in socks for several hours to give them the scent of human foot odor.
However, we show that olfactory stimulation with particular
odorants results
in modulation of dozens of OSN subtypes
in a subtle but reproducible, specific and time - dependent manner.
In principle, odorant isotopomers provide a possible test of shape vs. vibration mechanisms: replacing, for example, hydrogen with deuterium in an odorant leaves the ground - state conformation of the molecule unaltered while doubling atomic mass and so altering the frequency of all its vibrational modes to a greater or lesser extent [11
In principle,
odorant isotopomers provide a possible test of shape vs. vibration mechanisms: replacing, for example, hydrogen with deuterium
in an odorant leaves the ground - state conformation of the molecule unaltered while doubling atomic mass and so altering the frequency of all its vibrational modes to a greater or lesser extent [11
in an
odorant leaves the ground - state conformation of the molecule unaltered while doubling atomic mass and so altering the frequency of all its vibrational modes to a greater or lesser extent [11].
With similar precision, Professor Bargmann has also identified many of the intracellular signalling pathways
in C. elegans that relay information from cell surface
odorant receptors (G protein - coupled receptors) to the interior of each sensory neuron.
We developed new methodologies and procedures that allowed us to investigate the specificity of odour recognition between
odorant binding proteins and receptors
in Anopheles gambiae mosquito.