The compound, which is widely prescribed for breast cancer, is known to block
oestrogen receptors on many cancer cells, so inhibiting their growth.
Because of a quirk of evolution, these plant chemicals are close enough to the natural hormone's shape to bind to
the oestrogen receptors on cells in the human body.
Not exact matches
Breast Cancer Care comment
on claims that long - term use of Tamoxifen may increase proportion of
oestrogen receptor (ER) negative cancers which develop in the opposite breast
His lab hopes to knock out a specific
oestrogen receptor in dogs to understand the hormone's effects
on fertility.
The data included information
on the age of diagnosis, region of residence, deprivation, ethnicity, tumour size, grade,
oestrogen receptor status (ER), Herceptin
receptor status (HER2), and whether or not the cancer had spread to the lymph nodes.
My translational research has focused
on trying to find better ways to estimate recurrence risk in patients diagnosed with
oestrogen -
receptor positive early breast cancer, with the ultimate aim to better personalise our therapies for those patients who have the most to gain from them.
The
oestrogens that negatively impact
on our body either settle in the
receptor sites reserved for natural
oestrogen production, or can have very damaging effects
on the body as the liver attempts to detoxify them.
(4) The demonstration of a melatonin
receptor in human ovary suggests a direct influence of this hormone
on the ovarian function, and possibly
oestrogen production.
Three Presentations, a double - sided worksheet
on epigenetics and a fun class quiz which cover the following topics: Transcription Factors and the
Oestrogen Receptor, DNA methylation and Histone Acetylation (epigenetics), RNA interference, as well as how these are implicated in cancers.