Not exact matches
This
active IND enables Aura to begin initial clinical testing
of AU - 011, a unique targeted
therapy that could transform the primary treatment
of patients with OM, a rare and life - threatening disease.
Members
of all the counseling -
therapy professions should take
active leadership in developing such a network in the churches, high schools, colleges, adult education programs, and in all health care and counseling agencies
of their communities!
She is an
active member
of both the American Association for Play
Therapy and the British Association
of Play Therapists and has presented at numerous workshops and conferences for professionals and parents.
less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral
therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug
therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral
therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug
therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly
Active Antiretroviral
Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug
Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission
of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention
of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one
of the three major macromolecules (along with DNA and proteins) that are essential for all known forms
of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)
Melissa's interest for massage
therapy piqued at an early age while being
active in sports and how massage aided in the relaxation
of sore muscles.
These daily
therapy sessions usually consist
of waiting until LF # 5 is
active and awake.
Radiation
therapy, along with surgery, hormone
therapy, and
active surveillance — known as watchful waiting — has been a mainstay
of treatment for prostate cancer in the United States.
The big breakthrough came in 1996, when researchers realised that the best way to suppress HIV replication was to use a combination
of drugs — an approach known as highly
active antiretroviral
therapy (HAART).
As a result, the authors suggest that healthcare providers — in particular family medicine practitioners — need to be more aware
of the various CAM
therapies and take a more
active role in guiding patients through their options to more safely and effectively coordinate their care.
«HPV -
active tumors have high expression
of immunoregulatory genes and therefore may respond to immune checkpoint inhibitor
therapy.
Strikingly, the treatment approach didn't make a difference to 10 - year survival: Ninety - nine percent
of the more than 1600 men in the trial were alive after a decade, whether they had initially received radical surgery, radiation, or
active monitoring, which meant no immediate
therapy, but intervention as needed.
The investigators» experiments in mice suggest that the receptors» activation directly aggravates airway constriction and — if the same process is
active in people — may be a promising new target for the development
of drug
therapies.
«One criticism
of the PARP drugs is they are not
active in patients who have developed resistance to other
therapies, but we found veliparib appears to be effective in some platinum - resistant patients with recurrent or persistent disease,» said Robert L. Coleman, MD, lead author
of the study and professor and vice chair
of clinical research at the University
of Texas MD Anderson Cancer Center, Houston.
To find the best
therapy for each one
of these 33 tumor facets, the researchers tested about 180 different
active substances.
The researchers report that these two
therapies together represent a highly
active combination for refractory or relapsed Hodgkin lymphoma, with a complete response rate exceeding that seen with standard
therapy or following administration
of either brentuximab vedotin or gemcitabine alone.
«Rheumatologists can be reassured that treatment
of active rheumatoid arthritis with anti-TNF
therapy may lead not just to an improvement in joint symptoms, but also a reduction in the rate
of myocardial infarctions in the medium term,» says Dr. Dixon
But
therapies that target common molecular pathways
active late in disease could be part
of a multi-pronged treatment plan for people with these inherited conditions.
Previous studies, he adds, have shown that taking testosterone at the wrong time — particularly by men with symptoms
of active cancer progression who have not yet received testosterone - blocking
therapy — can make the disease worse.
In an early benefit assessment pursuant to the «Act on the Reform
of the Market for Medicinal Products» (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this new
active ingredient offers an added benefit over the appropriate comparator
therapy.
We have found that exosomes and the cargo they contain are crucial mediators
of stem cell - based heart regeneration, and we believe this might lead to an even more refined
therapy using the «
active ingredient» instead
of the entire stem cell,» said Eduardo Marbán, MD, PhD, director
of the Cedars - Sinai Heart Institute and a pioneer in developing investigational cardiac stem cell treatments.
Highly
active antiretroviral
therapy (HAART) has transformed the outlook for patients infected with HIV by suppressing the replication
of the virus in the body.
As for the future
of adolescent substance use treatment, Drs. Chung & Black describe a need to focus on the «
active ingredients»
of therapies and their respective «targets.»
This new more powerful drug heralds the start
of Highly
Active Antiretroviral
Therapy (HAART)-- a combination therapy regimen using a «cocktail» o
Therapy (HAART)-- a combination
therapy regimen using a «cocktail» o
therapy regimen using a «cocktail»
of drugs
The two cell types are important to a broad range
of organ systems in the body and play
active roles in diseases that could be targets for nucleic acid
therapies.
To identify this T cell population, the researchers took biopsies at the sites
of active lesions before treatment and biopsies
of the same skin areas after the lesions had cleared on
therapy.
The anxiety and uncertainty that men who choose
active surveillance experience when diagnosed with prostate cancer causes one in four to receive definitive
therapies within one to three years, even when there is no sign
of tumor progression.
These results clearly demonstrated that octacosanol is an
active compound that has potential to reduce stress and to increase sleep, and it could potentially be useful for the
therapy of insomnia caused by stress.
The crisis response plan was a central ingredient
of another successful treatment developed by many
of the same researchers at the National Center for Veterans Studies — brief cognitive behavioral
therapy — which contributed to a 60 percent reduction in suicide attempts among
active duty soldiers.
During the study, the participants were observed while on highly
active antiretroviral
therapy, or HAART, which normally consists
of three or more drugs and is currently the most common — and most effective — treatment for HIV - positive adults.
Here, six patients suspended combination antiretroviral
therapy for 12 weeks after infusion with altered CD4 cells, so scientists could monitor viral load and the power
of the altered immune cells to survive and thrive in the presence
of active HIV.
Doctors had prescribed a combination
of HIV / AIDS drugs called highly
active antiretroviral
therapy, but for the previous seven years, the patient had not taken his medications.
«This is a significant example
of how knowing details
of potential mechanisms and the basic science
of redox
active compounds in cancer versus normal cells can be leveraged clinically in cancer
therapy,» says co-senior author Douglas Spitz, who focused on the biochemical studies.
Now, we don't know all the things zonulin does yet, it probably does many things in the body, probably it is
active in many processes; but this one seems like it may potentially be a key to
therapies or one
of the keys to
therapies for celiac disease.
The
therapy itself varied depending on the individual needs
of the patient so the researchers can't say exactly what the «
active ingredient» was that inoculated many against future suicide attempts.
«We have evidence that the stem cells did in fact convert the prodrug to an
active chemotherapeutic agent in the brain,» says Karen Aboody, the translational researcher at City
of Hope who developed the
therapy.
The scientists had accidentally landed upon a potential new
therapy for type A
of the neurotoxin, the most common and deadly cause
of human botulism, using copper chloride, an inexpensive, readily available metal salt as the
active ingredient.
They found that 12 patients on
active abiraterone
therapy had detectable serum levels
of D4A.
After analyzing the data, he and his collaborators in Berlin are convinced that the activity
of Shp2 and its target genes can predict the outcome
of breast cancer: The less
active Shp2 is, the higher the chance for the affected women to stay relapse - free after having undergone a successful breast cancer
therapy.
A Phase II Single - Arm Trial to Investigate Tepotinib in advanced (Stage IIIB / IV) Non-Small Cell Lung Cancer with MET Exon 14 (METex14) Skipping Alterations After Failure
of at Least One Prior
Active Therapy, Including a Platinum - Doublet - Containing Regimen
Previous history
of myocardial infarction within 1 year prior to study entry, uncontrolled hypertension or uncontrolled arrhythmias • Pulmonary disease (e.g. COPD, asthma, etc) that is not controlled (moderate to severe symptoms) with current medication •
Active, uncontrolled bacterial, viral, or fungal infections, requiring systemic
therapy
Format: Website Years Covered: currently
active UK trials as
of June 2017 Search Strategy: Not disclosed Project Focus: advanced cell
therapy,
active that year, in the UK only Special Notes: on - line sort by 4 parameters, archives for previous years back to 2012.
He walked the audience through his recently developed model that can predict antiviral activity
of three - drug combinations in highly
active antiretroviral
therapy (HAART).
Therapies applying this paradigm to clear β - amyloid protein (Aβ) plaques and soluble aggregates from patients with Alzheimer's disease (AD) is an extremely
active field
of research, with multiple
active and passive Aβ vaccines currently in human clinical trials.
Given this, it seems very plausible that in the decades ahead there will be many partially rejuvenated,
active, healthy people at advanced ages walking around, all bearing very high levels
of nuclear DNA damage, but protected from the consequent cancer incidence by highly effective next generation
therapies.
Patient Care and Follow - up - After
active treatment ends, patients transfer to the St. Jude LIFE & After Completion
of Therapy Clinic Presented by Kmart (ACT Clinic).
• Patients must have adequate coagulation (international normalized ratio (INR) or prothrombin time (PT), partial thromboplastin time (PTT) ≤ 1.5 times ULN) • Adequate liver function (total bilirubin ≤ 1.5 times the ULN, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times ULN Exclusion Criteria: • Presence
of active / uncontrolled central nervous system involvement • History
of clinically significant cardiac disease; uncontrolled hypertension • Left ventricular ejection fraction (LVEF) < 45 % • Allogeneic stem cell transplant within 100 days before first dose
of study drug • Known history
of human immunodeficiency virus (HIV) infection • Chronic or
active hepatitis B or C, requiring antiviral
therapy • Evidence
of history
of bleeding disorder, dialysis, or coexisting cancer that is distinct in primary site or histology from the cancer evaluated in this study • Serious, uncontrolled infection • Unresolved chronic toxicity > grade 1 from prior
therapy • Use
of strong CYP3A4 inhibitors or strong inducers within 7 days prior to the start
of study treatment and for the duration
of the study
The University
of Michigan C.S. Mott Children's Hospital Pediatric Oncology Program has an
active research program in pediatric neuroblastoma, with several novel protocols developed for the treatment
of patients who have failed primary
therapy.
Highly
active antiretroviral
therapy (HAART) has been highly successful in decreasing morbidity and mortality
of HIV / AIDS, although other synergistic strategies are required to completely remove any cellular reservoirs
of latent virus.
Allogeneic cell
therapies from primary cells for immunotherapy applications are especially challenging because
of the vigor with which tissue donors must be screened and qualified to prevent transmission
of infectious disease and ensure maintenance
of an
active donor pool.
Brenchley said the results
of the study suggest that supplementing highly
active antiretroviral
therapy with probiotics might improve the long - term prognosis
of HIV - infected individuals.