Sentences with phrase «of angiogenic»

According to experts, by modulating the secretion of angiogenic factors in ovarian cancer cells, ginger is can be one of the most potent natural ingredients against this disease.

More interestingly, the effects on infarction size, survival rates and cardiac function can be observed even if the dietary intervention is induced after the ischemic event, by increasing the expression of angiogenic factors and increased vascularization of the damaged myocardium, proposing a novel non-pharmacological therapy for subjects with chronic heart failure (43).

«Flavonoids and Vitamin E Reduce the Release of the Angiogenic Peptide Vascular Endothelial Growth Factor from Human Tumor Cells».

Secretion of Angiogenic and Antiapoptotic Factors by Human Adipose Stromal Cells (March 16, 2004) in Circulation.

We show for the first time that kahweol is an anti-angiogenic compound with inhibitory effects in two in vivo and one ex vivo angiogenesis models, with effects on specific steps of the angiogenic process: endothelial cell proliferation, migration, invasion and tube formation on Matrigel.

Cyclooxygenase -2-dependent expression of angiogenic CXC chemokines ENA - 78 / CXC Ligand (CXCL) 5 and interleukin - 8 / CXCL8 in human non-small cell lung cancer.

Different in vitro assays were carried out in order to test the specific effects of kahweol treatment on several key steps of the angiogenic process in both endothelial and tumor cells.

The research demonstrates that bioactive lipids have the ability to regulate inflammatory immune cells in the retina, key regulators of the angiogenic process in this disease.

In turn, tumour angiogenesis is characterized by a pathological patency of the angiogenic stimulus resulting in a chaotropic, pro-angiogenic and permanently immature vasculature.

Vice versa, pericyte recruitment by nascent vessels occurs during the later steps of the angiogenic cascade providing stabilization and maturation signals2.

«This is the first demonstration of the profile of angiogenic molecules expression using neural stem cells derived from patients with schizophrenia, which shows they have a less angiogenic profile when compared to controls,» says Palma.

Not exact matches

«Using a novel model we developed to facilitate discoveries about the growth and spread of lymph node metastases, we show that angiogenesis does not occur in lymph node metastases, providing a mechanism for resistance to angiogenic therapy in these situations.»

Therefore, those were chosen to test whether the molecules produced by the neural stem cells of patients alter the angiogenic capacity of the cells.

Dr Sidibé describes how: «The ability of tumours to recruit angiogenic monocytes is due to the ability of the tumours themselves to produce cytokines.

Decreased phosphorylation of PDGFR - ß impairs the angiogenic potential of expanded endothelial progenitor cells via the inhibition of PI3K / Akt signaling.

But, it was known that when HIF - 1 normally activates signals in the body to build new vessels, one of the many types of cells recruited to the site of new vessel growth is a population of stem cells from the bone marrow, which are called bone marrow - derived angiogenic cells.

Collectively, the experiments identified a more angiogenic and leaky, yet well perfused vasculature in tumours of mice with targeted deletion of Tie2 in pericytes.

A major aspect of this process is the production of multiple angiogenic cytokines and growth factors in response to hypoxia / ischemia, which is mediated by the transcription factor HIF - 1 (hypoxia - inducible factor 1).

In a new STEM CELLS Translational Medicine study, Zhang et al. now report that the overexpression of Platelet - Derived Growth Factor - BB (PDGF - BB), a well - known potent mitogenic, angiogenic, and chemoattractive agent, can significantly enhance dental tissue regeneration [5].

Furthermore, this study demonstrated that a biocompatible PA - RGDS nanomatrix gel substantially improved long - term survival of hPSC - ECs in an ischemic environment and improved neovascularization effects of hPSC - ECs via prolonged and unique angiogenic and vessel - forming properties.

Medical research has shown adult stem cells to be angiogenic, meaning they stimulate the growth of new blood vessels.

Angiogenesis involves local proliferation of endothelial cells in response to an angiogenic stimulus.

A key feature of endothelial cells switched to their angiogenic phenotype is their ability to invade the surrounding space.

A review of the microcirculation of adipose tissue: anatomic, metabolic, and angiogenic perspectives.

Echinacea stimulated the angiogenic (formation of new blood vessels) of spleen lymphocytes, indicating an enhancement of the immune system which would help fight off the kennel cough infection.