Genetic Mystery Solved for Type
of Brain Cancer Researchers identified the specific mutated genes that allow the brain cancer oligodendroglimoma to develop.
Not exact matches
While it has shown promise for some types
of tumors and become standard
of care for others,
researchers are just beginning to explore how different immunotherapy technologies can be applied to
brain cancer.
An experimental drug in early development for aggressive
brain tumors can cross the blood -
brain tumor barrier, kill tumor cells and block the growth
of tumor blood vessels, according to a study led by
researchers at the Ohio State University Comprehensive
Cancer Center — Arthur G. James
Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).
The
researchers have no plans to start testing Zika in people with
brain cancer as they are concerned the virus could pass to pregnant women: a mosquito species that carries Zika is found in some parts
of the US, and the virus can also be transmitted sexually.
HBI member V. Wee Yong, PhD and research associate Susobhan Sarkar, PhD, and their team including
researchers from the Department
of Clinical Neurosciences and the university's Southern Alberta
Cancer Research Institute, looked at human
brain tumor samples and discovered that specialized immune cells in
brain tumor patients are compromised.
Researchers at the University
of Calgary's Hotchkiss
Brain Institute (HBI) have made a discovery that could lead to better treatment for patients suffering from brain ca
Brain Institute (HBI) have made a discovery that could lead to better treatment for patients suffering from
brain ca
brain cancer.
Led by post-doctoral fellows, Martina Absinta, Ph.D. and Seung - Kwon Ha, Ph.D., along with
researchers from the National
Cancer Institute, the team discovered lymphatic vessels in the dura, the leathery outer coating
of the
brain.
An international team
of researchers has identified eight additional types
of cancer linked to excess weight and obesity: stomach, liver, gall bladder, pancreas, ovary, meningioma (a type
of brain tumor), thyroid
cancer and the blood
cancer multiple myeloma.
«We did not detect any clear change in the long - term time trends in the incidence
of brain tumors from 1998 to 2003 in any subgroup,» the
researchers wrote in the paper, which was published online Thursday in the Journal
of the National
Cancer Institute (JNCI).
By assessing the survival
of the cells that engulf the particles and measuring the levels
of red or green light that they emitted, the
researchers determined which formulation
of particles performed best, then tested that formulation in mice with human
brain cancer derived from their patients.
A team under Professor Scheffler, consisting
of researchers from the Bonn University Hospital, the Life &
Brain Center, The German Consortium for Translational Cancer Research, Tufts University Boston / Massachusetts, and other institutes in the USA, has now developed a new method that is expected to combat such complex brain tumors be
Brain Center, The German Consortium for Translational
Cancer Research, Tufts University Boston / Massachusetts, and other institutes in the USA, has now developed a new method that is expected to combat such complex
brain tumors be
brain tumors better.
A team
of researchers in northern Europe, however, has now combed through three decades
of cancer registries and found no increase in the rate
of brain tumors in the five to 10 years following widespread cell phone adoption in that region.
Together with clinical
researchers, they are preparing treatments for glioblastoma — the most aggressive
brain cancer in adults — , Friedreich's Ataxia — a hereditary neurodegenerative disease — , and a type
of paediatric
brain cancer.
Researchers at the University
of Calgary's Hotchkiss
Brain Institute (HBI) and Southern Alberta Cancer Research Institute (SACRI) have made a discovery that could prolong the life of people living with glioblastoma — the most aggressive type of brain ca
Brain Institute (HBI) and Southern Alberta
Cancer Research Institute (SACRI) have made a discovery that could prolong the life of people living with glioblastoma — the most aggressive type of brain c
Cancer Research Institute (SACRI) have made a discovery that could prolong the life
of people living with glioblastoma — the most aggressive type
of brain ca
brain cancercancer.
Study results revealed previously unknown interplay between two key enzymes and a novel understanding
of how
brain cancer tumors form and spread, according to researchers at The University of Texas MD Anderson Cancer C
cancer tumors form and spread, according to
researchers at The University
of Texas MD Anderson
Cancer C
Cancer Center.
A molecule in cells that shuts down the expression
of genes might be a promising target for new drugs designed to treat the most frequent and lethal form
of brain cancer, according to a new study by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — J
cancer, according to a new study by
researchers at The Ohio State University Comprehensive
Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — J
Cancer Center — Arthur G. James
Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — J
Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).
Researchers have identified a group
of immune system genes that may play a role in how long people can live after developing a common type
of brain cancer called glioblastoma multiforme, a tumor
of the glial cells in the
brain.
So a team led by autoimmunity
researcher and rheumatologist J. Lee Nelson
of the Fred Hutchinson
Cancer Research Center in Seattle, Washington, took samples from autopsied
brains of 59 women who died between the ages
of 32 and 101.
To test this idea, the
researchers utilized two mouse models
of human breast
cancer metastasis and found dormant disseminated tumor cells residing upon the membrane microvasculature
of lung, bone marrow and
brain tissue.
By interfacing
brain cells onto graphene,
researchers at the University
of Illinois at Chicago have shown they can differentiate a single hyperactive cancerous cell from a normal cell, pointing the way to developing a simple, noninvasive tool for early
cancer diagnosis.
In this study, the
researchers from Imperial's Department
of Surgery and
Cancer and the Royal British Legion Centre for Blast Injury Studies, applied xenon to slices
of mouse
brain tissue after exposing them to blast shockwaves that emulated those produced by improvised explosive devices (IEDs).
In a new study published in Scientific Reports, Tokyo Medical and Dental University (TMDU)- led
researchers investigated photodynamic detection
of cancer stem cells in a glioma cell line, a model
of a highly aggressive type
of brain cancer.
The process, which located a genetic site for the most common form
of prostate
cancer, has potential for developing precision therapy for other cancers, such as breast, brain and colorectal, say researchers at The University of Texas MD Anderson Cancer C
cancer, has potential for developing precision therapy for other
cancers, such as breast,
brain and colorectal, say
researchers at The University
of Texas MD Anderson
Cancer C
Cancer Center.
That is why
researchers more often rely on faster - developing indicators
of (apparently) improved health: tumor shrinkage in
cancer, lowered blood - sugar levels in diabetes, reduced
brain plaque in Alzheimer's, lowered bad cholesterol or elevated good cholesterol in heart disease.
While
researchers debate whether microwaves emitted by cell phones might cause
brain cancer, a study published in the Journal
of the American Medical Association last February raised an entirely different concern.
Researchers from the University
of Portsmouth's
Brain Tumour Research Centre of Excellence have identified molecules which are responsible for metastatic lung cancer cells binding to blood vessels in the b
Brain Tumour Research Centre
of Excellence have identified molecules which are responsible for metastatic lung
cancer cells binding to blood vessels in the
brainbrain.
In a new International Journal
of Cancer analysis,
researchers found a link between maternal residential pesticide use — particularly insecticides — and the risk
of childhood
brain tumors.
Genetically modified «hunter» T cells successfully migrated to and penetrated a deadly type
of brain tumor known as glioblastoma (GBM) in a clinical trial
of the new therapy, but the cells triggered an immunosuppressive tumor microenvironment and faced a complex mutational landscape that will need to be overcome to better treat this aggressive
cancer, Penn Medicine
researchers report in a new study this week in Science Translational Medicine.
Knocking down the expression
of either the fruit fly version
of the FOXD1 gene or the fruit fly version
of ALDH1A3 blocks the formation
of brain tumors in a
brain cancer model
of the fruit fly species Drosophila melanogaster, the
researchers found.
«Often it is impossible to visually distinguish
cancer from normal
brain, so invasive
brain cancer cells frequently remain after surgery, leading to
cancer recurrence and a worse prognosis,» says Dr. Kevin Petrecca, Chief
of Neurosurgery and
brain cancer researcher at The Neuro, and co-senior author
of the study published today in Science Translational Medicine.
Researchers at University
of California San Diego School
of Medicine have demonstrated that distinct types
of glioblastoma, the most common form
of brain cancer in adults, tend to develop in different regions
of the
brain.
That may be great if you are using carbon nanotubes to deliver chemotherapy drugs to people with
brain tumors, as
cancer researchers in California (at City
of Hope, a
cancer research and treatment center in Duarte in collaboration with NASA's Jet Propulsion Laboratory in Pasadena), hope to do.
Researchers investigating pediatric low - grade gliomas (PLGG), the most common type
of brain tumor in children, have discovered key biological differences in how mutated genes combine with other genes to drive this childhood
cancer.
Through the study,
researchers were also able to pinpoint three different
brain changes caused by the progression
of cancer and the drugs used in treatment.
It encompassed more than 12,000 long - term regular cell phone users from 13 countries, about half
of whom were
brain cancer patients, which let
researchers compare the two groups.
To find out whether the virus could help treat
cancer in a living animal, the
researchers injected either Zika virus or saltwater (a placebo) directly into the
brain tumors
of 18 and 15 mice, respectively.
The
brain imaging study was led by researchers at University of Pennsylvania's new Brain and Behavior Change Program, led by Caryn Lerman, PhD, who is also the deputy director of Penn's Abramson Cancer Center, and Elliot Stein, PhD, and collaborators at
brain imaging study was led by
researchers at University
of Pennsylvania's new
Brain and Behavior Change Program, led by Caryn Lerman, PhD, who is also the deputy director of Penn's Abramson Cancer Center, and Elliot Stein, PhD, and collaborators at
Brain and Behavior Change Program, led by Caryn Lerman, PhD, who is also the deputy director
of Penn's Abramson
Cancer Center, and Elliot Stein, PhD, and collaborators at NIDA.
Researchers at The University
of Texas MD Anderson
Cancer Center prospectively evaluated the cardiac function biomarkers
brain natriuretic peptide (BNP), troponin - I (TNI), and electrocardiogram (ECG) in 25 patients receiving high - dose conformal radiation therapy for thoracic malignancies.
The altered metabolism
of two essential amino acids helps drive the development
of the most common and lethal form
of brain cancer, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — J
cancer, according to a new study led by
researchers at The Ohio State University Comprehensive
Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — J
Cancer Center — Arthur G. James
Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — J
Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).
«
Researchers develop a likely new combo treatment for the deadliest form
of brain cancer.»
In February a group
of researchers from Case Western Reserve University reported online in Science that a
cancer drug with relatively benign side effects was able to rapidly clear from the
brains of mice toxic amyloid - beta protein fragments that accompany Alzheimer's.
At this year's San Antonio Breast
Cancer Symposium, UNC Lineberger researchers and collaborators shared the outcomes of their investigation into the incidence of brain metastasis after a series of drugs were approved to treat HER2 - positive metastatic breast cancer, starting with trastuzumab, also known as Herceptin, in the United States in
Cancer Symposium, UNC Lineberger
researchers and collaborators shared the outcomes
of their investigation into the incidence
of brain metastasis after a series
of drugs were approved to treat HER2 - positive metastatic breast
cancer, starting with trastuzumab, also known as Herceptin, in the United States in
cancer, starting with trastuzumab, also known as Herceptin, in the United States in 1998.
Cancer researchers have found that certain types
of dental X-rays significantly increased the incidence
of the most common type
of brain tumor in the United States: meningioma.
Newswise —
Researchers at University
of California San Diego School
of Medicine have demonstrated that distinct types
of glioblastoma, the most common form
of brain cancer in adults, tend to develop in different regions
of the
brain.
Researchers at Sylvester Comprehensive
Cancer Center at the University
of Miami Miller School
of Medicine have discovered a peripheral biomarker in human blood serum that can be used to detect the presence and progress
of glioblastoma
brain tumors before and after treatment.
Researchers funded by the Canadian
Cancer Society have discovered eight similar genes that, when mutated, appear to be responsible for medulloblastoma — the most common
of childhood
brain cancers.
An international team
of researchers has found a drug previously approved to treat breast
cancer could also be used to shrink medulloblastoma, a common form
of childhood
brain tumour.
The team compared «age and gender - specific incidence rates
of 19,858 male and 14,222 females diagnosed with
brain cancer between 1982 and 2012, and mobile phone usage data from 1987 to 2012,» writes lead
researcher Simon Chapman in the study, published by
In addition to developing the new genetically engineered mouse model for the form
of cancer called glioblastoma multiforme, the
researchers made a key discovery about
brain tumor biology via the mice.
University
of Hawai'i
Cancer Center researchers have identified an essential driver of tumor cell invasion in glioblastoma, the most aggressive form of brain cancer that can occur at an
Cancer Center
researchers have identified an essential driver
of tumor cell invasion in glioblastoma, the most aggressive form
of brain cancer that can occur at an
cancer that can occur at any age.