Roberto Polakiewicz, chief scientific officer
of Cell Signaling Technology, points out that the cultures of different corporations can vary markedly.
Not exact matches
The NYPD is one
of many police departments across the country quietly using a highly secretive military grade
technology that can track the whereabouts
of suspects by using their
cell phone
signals.
Components
of indoor dust may
signal human fat
cells to grow and may alter metabolism, potentially contributing to weight problems, researchers report July 14 in Environmental Science &
Technology.
«There's a large amount
of validation to ensure specificity
of the antibodies and to make sure that the antibody is actually recognizing the intended target,» says Craig M. Thompson, director
of production and molecular assays, with
Cell Signaling Technology (CST), located in Danvers, Massachusetts.
A team led by chemist Thomas Meade
of the California Institute
of Technology in Pasadena figured out how to amplify the MRI's
signal only in
cells where a certain enzyme is active.
To better coordinate bacteria, bioengineers Lingchong You and Frances Arnold
of the California Institute
of Technology and colleagues rewired a natural
cell -
signaling pathway from Vibrio fisheri, bacteria in the light organ
of deep - sea squid.
Using state -
of - the - art micro-computed tomography and digital imaging
technology applied to hundreds
of fossil and recent molars, Ortiz and colleagues created virtual maps
of the dental landscape
of developing teeth to chart the precise location
of embryonic
signaling cells from which molar cusps develop.
Before starting
Cell Signaling Technology in 1999, Michael directed the Molecular Neurobiology Lab at Massachusetts General Hospital and served as an Associate Professor
of Neuroscience at Harvard Medical School.
The primary antibodies were used at a dilution
of 1:1,000 unless otherwise stated and their sources and molecular weights were as follows:
Cell Signaling Technology (Danvers, MA, USA): β - actin, monoclonal HRP conjugate, 45 kDa; CREB, monoclonal, 43 kDa.
Phosphorylation
of signaling proteins was investigated using the following phospho - specific antibodies from Cell Signaling Technology: anti-pY1034 / 1035 JAK1 (# 3331S), anti-pY1007 / 1008 JAK2 (# 3771S), anti-pY705 STAT3 (# 9131S), anti-pY694 STAT5 (# 9351S) and anti-p44 / 42 MAPK (
signaling proteins was investigated using the following phospho - specific antibodies from
Cell Signaling Technology: anti-pY1034 / 1035 JAK1 (# 3331S), anti-pY1007 / 1008 JAK2 (# 3771S), anti-pY705 STAT3 (# 9131S), anti-pY694 STAT5 (# 9351S) and anti-p44 / 42 MAPK (
Signaling Technology: anti-pY1034 / 1035 JAK1 (# 3331S), anti-pY1007 / 1008 JAK2 (# 3771S), anti-pY705 STAT3 (# 9131S), anti-pY694 STAT5 (# 9351S) and anti-p44 / 42 MAPK (# 9101L).
However some technical challenges still need to be taken to make the
technology more accessible and usable to its full potential: gaining selective and comprehensive genetic access to the neurons
of interest, controlling variation in the expression
of the optogenetic tools (when using viruses) and its precise localization (axon vs. presynaptic terminals), tailoring light - delivery system
signals to individual
cells in a population rather than the population as a whole, developing observation techniques which have the same spatial and temporal resolution as those tools... to cite only a few
of them.
Amplified Luminescent Proximity Homogeneous Assay Screen (AlphaScreen) AlphaScreen is a versatile assay
technology developed to measure analytes using a homogenous protocol that enables sensitive and precise interrogation
of signaling pathways, receptors, enzymes and kinase targets, in a
cell - based format.
In the fall, Google was sued by Skyhook Wireless — the Boston - based outfit that pioneered the art
of pinpointing a mobile device's location based on Wi - Fi and
cell - tower
signals — which accused using Android to strong - arm handset makers into choosing Google's location
technology rather than Skyhook's.
It's estimated that nearly 97 percent
of cell phone
signals never reach a destination and are simply lost, but with this
technology some
of that can be recaptured and used for keeping
cell phone's going without needing to be plugged in.
Cellular densification arising from the 5G network is expected to grow at a compound annual rate
of 36 percent, resulting in 8.5 million small -
cell sites (antenna equipment used to transmit
cell phone
signals) by 2025, according to Rethink
Technology Research.