Citation: Hough SR, Laslett AL, Grimmond SB, Kolle G, Pera MF (2009) A Continuum
of Cell States Spans Pluripotency and Lineage Commitment in Human Embryonic Stem Cells.
Think
of the cell state as the memory.
Not exact matches
In a decision released by the Baltimore Circuit Court, Judge Martin P. Welch wrote that the 35 - year - old was being granted a new trial because his initial council failed to properly cross-examine an expert from the
state about the reliability
of cell tower data that seemed to place him at the scene
of the crime.
When lumped in with still - rising federal levies like the Universal Services Fund, they add 12 percent to the average American's
cell bill and as much as 19 percent in many
of our most populous
states, says Scott Mackey, economist and partner with government affairs firm Kimbell Sherman Ellis.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for
state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and
state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect
of lowering prices or reducing the number
of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize
cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Most
of the wireless industry is looking for new markets, as the number
of cell phones now far exceeds the number
of people in the United
States and revenue growth is hard to find.
In the second half
of 2017, the United
States Food and Drug Administration (FDA) approved two immunotherapies that use genetically engineered T
cells (CAR - T
cell therapy) to fight cancer.
This statement is in sharp contrast to the statements
of analysts at IHS Markit and GTM Research that new
cell and module factories in the United
States do not make economic sense despite the imposition
of tariffs on imported modules.
Alexanda Amon Kotey, a British national, is one
of four members
of an execution
cell for the Foreign Terrorist Organization (FTO) and SDGT group, the Islamic
State of Iraq and the Levant (ISIL).
It was
state of the art in 2008, but
cell technology has improved substantially since then.
Earlier in his career, Scott served as the founding Executive Vice President at Solar
Cells, Inc. (now First Solar), the President
of Glasstech Solar, Inc. (a manufacturer
of semiconductor equipment for the solar industry), and consultant to venture capital firms and
state agencies on renewable technologies and markets.
I was very niave as alot
of commenters are here today
stating that abortions only take place on a blob
of cells.
Many times we hear pro-choice «rs
state that it is just a collection
of cells.
Nanog is said to act at a later stage
of development to keep
cells in an undifferentiated
state.
In May 2007 Newsweek Healthcarried an article
stating that heart
cells can remain alive for several hours even without oxygen, and that it is the sudden resumption
of the oxygen supply, as attempts are made to resuscitate the individual in hospital, that causes apoptosis, killing the
cells and causing death.
CNN: Sandusky's pastor addresses conviction from pulpit Jerry Sandusky sits in a county jail
cell in Bellefonte, Pennsylvania, but his presence and the weight
of the 45 guilty verdicts rendered against the former Penn
State football coach on Friday night hung in the air Sunday morning at the
State College church where he and his wife are longtime members.
Whether I use the expression «momentary self» or the word «monad,» what I am in fact doing is setting a limit, on no validly argued grounds, to the dissolution
of the «total temporary
states» into a purely ad hoc combination
of inexplicable and inexplicably organized collections
of bodily
cells, sensations, intentions, thoughts, nervous processes, desires, and the like.
The facts you
state about the minimum number
of proteins needed to build a
cell are also incorrect.
A new flight restriction out
of the Trump administration will keep passengers on United
States - bound flights from eight Muslim - majority countries from carrying on any electronics bigger than a
cell phone.
In 2014, a team
of researchers at UCLA led by genetics researcher, Steve Cole, discovered that the
cells of people who experience chronic loneliness appear to be stuck in a
state of fear.
«Garcia - Falgueras and Swaab
state in the abstract
of their 2010 study, «The fetal brain develops during the intrauterine period in the male direction through a direct action
of testosterone on the developing nerve
cells, or in the female direction through the absence
of this hormone surge.
Indeed, the ability to clone animals, such as Dolly the sheep, by fusion
of an adult
cell to an enucleated oocyte demonstrates that the epigenetic programming responsible for maintaining an adult
cell in a stable
state can be erased by factors present in the cytoplasm
of the oocyte.
By virtue
of a complicated arrangement
of cells in the brain, there is at the human level emergent a mental
state marked by what I have styled awareness.
During cloning, the adult nucleus is converted to a totipotent
state that will then proceed through a clear progression
of developmental steps to yield pluripotent stem
cells at a later time.
«Garcia - Falgueras and Swaab
state in the abstract
of their 2010 study, «The fe - tal brain develops during the intraut - erine period in the male direction through a direct action
of tes - tosterone on the developing nerve
cells, or in the female direction through the absence
of this hor - mone surge.
The ultimate goal
of our laboratory is to generate ES - like
cells directly from somatic
cells by nuclear reprogramming... which converts adult
cells back into embryonic
state.
State College, Pennsylvania (CNN)-- Jerry Sandusky sits in a county jail
cell in Bellefonte, Pennsylvania, but his presence and the weight
of the 45 guilty verdicts rendered against the former Penn
State football coach on Friday night hung in the air Sunday morning at the
State College church where he and his wife are longtime members.
We can not stay where we are at present, either physically or psychically; but looking far ahead we may descry an ultimate
state in which, organically associated with one another (more closely than the
cells of a single brain) we shall form m our entirety a single system, ultra-complex and, in consequence, ultra-centrated....
In part, his idea is that sensation is always «representative»
of objects outside the body but directly «presentative»
of the actual
states of cells within the body.24 But now we come to the truly sensational aspect
of his understanding
of sensation!
Hence, Hartshorne says that God has direct access to all parts
of the world through immediate social relations after the fashion
of human minds» being immediately aware
of the
states of their brain
cells.
One
of the consequences
of their work is
stated in their press release: «With this first synthetic bacterial
cell and the new tools and technologies we developed to successfully complete this project, we now have the means to dissect the genetic instruction set
of a bacterial
cell to see and understand how it really works.»
When I entered the United
States Senate in 1996, I had no idea that I would eventually consider stem
cell research as one
of the most important policy issues in which I am involved.
The first page
of Larsen's Human Embryology
states that, `... [W] e begin our description
of the developing human with the formation and differentiation
of the male and female sex
cells or gametes [sperm and egg], which will unite at fertilisation to initiate the embryonic development
of a new individual».
Though there have been many strides made towards ending the HIV / AIDS epidemic, such as the recent breakthrough
of scientists using gene editing to remove HIV from the genome
of T -
cells, there is still much work to be done with over 1.2 million in the United
States living with the disease.
We collect personally identifiable information that our visitors volunteer to us, including, but not limited to name, date
of birth, address, city,
state, zip code, telephone numbers,
cell phone numbers, gender, household income ranges, consumption habits, product usage, attitudes and preferences regarding our products and other personal information (collectively, «Personal Information»).
In Gut and Psychology Syndrome, Dr. Natasha Campbell - McBride
states that, «meats and fish stocks provide building blocks for the rapidly growing
cells of the gut lignin and...
Because cancer
cells in general are metabolically inflexible, we are able to take advantage
of ketone metabolism as a way
of placing cancer
cells in a weakened
state.
While study results indicated that combining capsaicin with the chemicals «might promote cancer
cell survival,» the report clearly
stated that the control group
of mice treated only with capsaicin ``... did not induce any skin tumors...» In addition, the study repeatedly cited other research studies in which the anti-cancer properties
of capsaicin were solidly demonstrated.
I watched this game, with unfettered excitement and inebriation, from The Rathskellar in
State College, Pennsylvania, and proceeded to spike my
cell phone into a million pieces in the middle
of the bar.
Take my teen's
cell phone: He received it in 6th grade, which may be early or late depending on your beliefs / community / needs, but he was going out
of state with a friend's family and I wanted him to be able to contact me (and me him) at any time.
Although most
states require only a handful
of tests, a panel
of experts convened by the U.S. Department
of Health and Human Services and the March
of Dimes recommends newborns be screened for 30 genetic disorders, including hypothyroidism, cystic fibrosis, and sickle
cell anemia.
A friend
of mine (she now has two PhDs, both from excellent institutions) implied that I was a racist and colonial imperialist because I stated that your eye colour is dependent on the DNA in your cell nuclei WHETHER YOU»VE EVER HEARD OF DNA OR NOT (ie, DNA exists whether you believe in it or not
of mine (she now has two PhDs, both from excellent institutions) implied that I was a racist and colonial imperialist because I
stated that your eye colour is dependent on the DNA in your
cell nuclei WHETHER YOU»VE EVER HEARD
OF DNA OR NOT (ie, DNA exists whether you believe in it or not
OF DNA OR NOT (ie, DNA exists whether you believe in it or not).
Dr. Devra Davis PhD., MPH, founder
of Environmental Health Trust (EHT) and an award - winning, internationally renowned scientist who also was the founding director
of the Board on Environmental Studies and Toxicology
of the U.S. National Research Council, National Academy
of Sciences,
states: «No studies show that microwave radiation exposure in children is safe or that continuous exposure from
cell phones,
cell towers, cordless phones, Wi - Fi routers, baby monitors, etc. is safe.»
In the article, Dr. Margot Sunderland, author
of the best - selling book What Every Parent Needs To Know,
stated that leaving a child in a
state of distress for a prolonged period without offering comfort affects them on a cellular level, specifically the «migration»
of their
cells as they get to where they need to be.
New York's 16 Medical schools released a report highlighting the economic and scientific benefits
of the
state's thus far, $ 223 million investment in STEM
Cell research.
In the case
of ISIS and Twitter, imagine a retaliatory attack on a hacker
cell that ends up killing civilians in large numbers by accident, creating international pressure against the U.S. bombing campaign against the Islamic
State.
At 9 a.m.,
state legislators and survivors
of solitary confinement unveil a replica solitary confinement
cell and call for Gov. Andrew Cuomo to spend 24 hours in solitary confinement, Legislative Office Building, Albany.
The reporter, Daily News Capitol Bureau Chief Ken Lovett, who has been covering
state government for decades, was arrested by the State Police for talking on his cell phone in the lobby of the Capitol outside the state Senate, in violation of a Senate
state government for decades, was arrested by the
State Police for talking on his cell phone in the lobby of the Capitol outside the state Senate, in violation of a Senate
State Police for talking on his
cell phone in the lobby
of the Capitol outside the
state Senate, in violation of a Senate
state Senate, in violation
of a Senate rule.
Off topic questions included his speech tomorrow to Britain's Labour Party, Chirlane McCray's attendance at an NYPD CompStat meeting, whether ISIS and the recent U.S. military strikes will cause a ramped - up security / counter-terrorism effort by the City, Governor Cuomo's efforts at supporting a Democratic
state senate, Congressional approval
of military strikes ordered by President Obama, the City school system's policy on student
cell phones and continuing problems at Rikers Island.
Sampling was conducted via a stratified dual frame probability sample
of landline and
cell phone telephone numbers (both from Survey Sampling International) from within New York
State weighted to reflect known population patterns.