Sentences with phrase «of cell renewal»

A Diet rich in Vitamins, Proteins and Nutrients are Good Promoters of Cell renewal which Speeds up Skin Repair and Texture enhancement in Aging or Damaged skin.

A Diet rich in Vitamins, Proteins and Nutrients are Good Promoters of Cell renewal which Speeds up Skin Repair -LSB-...]

These so - called «living drugs» — injected T cells genetically modified to better recognize and kill tumor cells through a perpetual process of cell renewal and expansion — are revolutionizing cancer treatment, with the first two FDA approvals of such gene - altering therapies occurring in just the last two months.

Not exact matches

It's full of those same minerals and amino acids that are the building blocks for cell regeneration and renewal.

It has been assumed that activation of HOX genes turns normal blood cells into leukemia cells by initiating stem cell - like self - renewal.

In leukemia cells it is often the case that genes are reactivated that, in physiological terms, mediate the self - renewal of blood stem cells.

They are particularly responsible for the self - renewal of blood stem cells.

Cancer stem cells can reproduce themselves through a process called self - renewal and sustain the growth of a tumor.

Autism risk mutations inactivate this gene and, in the absence of their own ability to produce carnitine and without adequate outside supplementation, neural stem cells become less efficient at self - renewal.

Also limiting the use of therapeutic stem cells to date, self - renewal, a quality so vital to a fast - growing fetus, can also be a source of cancer risk when haphazard, unlimited cell multiplication results in the abnormal tissue growth seen in tumors.

In the online issue of the journal Nature, the researchers report a new function of FAM134B in the constant renewal of the endoplasmic reticulum (ER), an important cell organelle.

The scientists have discovered that the colon has a safety mechanism to prevent the self - renewal of adenoma stem cells.

The study focuses on «stemness,» defined as the potential for self - renewal and differentiation from the cell of origin, and on «stemness indices» developed during postdoctoral research conducted by Tathiane Malta as part of a project supported by FAPESP and with Houtan Noushmehr, a professor in FMRP - USP's Genetics Department, as principal investigator.

To see whether cancer stem cell renewal involves a chain of events similar to that used by embryonic stem cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two human breast cancer cell lines that responded to low oxygen by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.

This widespread lack of the need for telomerase is used by evolution as a key component of our defense against cancer, because having a limit to the size and renewal of telomeres prevents our cells from replicating themselves indefinitely — the crucial hallmark of cancer.

And with adult stem cells, they don't have the same capacity of self - renewal to double and redouble infinitely.

To form an organoid, the stem cells are grown inside three - dimensional gels that contain a mix of biomolecules that promote stem cell renewal and differentiation.

«Cancer stem cells are capable of self - renewal, cellular differentiation and maintain their stem cell - like characteristics even after invasion and metastasis.»

Through folate, mitochondria produce substances to make ingredients for genome replication and repair, cell membrane renewal and synthesis of antioxidants.

In addition, many niches contain different stem cell types, each necessary to produce the distinct types of cells needed for tissue renewal.

In CRC 873, funded by the German Research Foundation, medical and biological scientists investigate the basic regulatory mechanisms that control the self - renewal and differentiation of stem cells.

Understanding the mechanisms that regulate the self - renewal and differentiation of stem cells is important, in order that stem cells can be effectively and safely utilised in medical applications in the future.

Whitehead Institute researchers have determined that the transcription factor Nanog, which plays a critical role in the self - renewal of embryonic stem cells, is expressed in a manner similar to other pluripotency markers.

They found that the protein seems to help maintain several traits in normal breast cells, including the ability to adhere to other epithelial cells, and the presence of molecules marking the cells as differentiated and not capable of self - renewal like breast stem cells.

The group examined how a protein called a Wnt is believed to maintain the self - renewal of embryonic stem cells.

In the current issue of the journal Nature, scientists at the Stowers Institute for Medical Research report that competition between two proteins, Bam and COP9, balances the self - renewal and differentiation functions of ovarian germline stem cells (GSCs) in fruit flies (Drosophila melanogaster).

The lab previously found that Bam is required to repress the expression of E-cadherin, a cell - to - cell adhesion molecule that tethers adult stem cells to their tissue niches and promotes GSC self - renewal.

The team discovered that the TCL1 protein played a key role in increasing glycolysis by activating a different metabolic pathway that is important for the self - renewal of stem cells.

The rigorous definition of a stem cell requires that it possesses two properties: Self - renewal - the ability to go through numerous cycles of cell division while maintaining the undifferentiated state.

Surfaces of these cells had lower concentrations of hyaluronan, a chemical substance that promotes tissue repair and renewal.

Self - renewal of blast crisis chronic myeloid leukemia cells was reduced by approximately 40 percent when treated with the small molecule, called 8 - Aza, as compared to untreated cells.

The proteasome plays a key role in the smooth running of a healthy cell, facilitating cell renewal and death — chopping up proteins tagged for destruction into short polypeptides which can then be converted to amino - acids and recycled for use in building new proteins.

The process that sets a stem cell on the path to either self - renewal or differentiation was thought to be a highly complex web of genetic and environmental interactions.

This is both a useful tool for giving us a better understanding of the genetic and epigenetic program controlling the self - renewal of stem cells, and on a practical side, it could allow us to inexpensively produce large numbers of immune cells, which could then be used for regenerative medicine or immune therapy.»

«The work is telling us that these [melanocyte] stem cells don't have an infinite capacity for self - renewal,» says geneticist Ian Jackson of the Medical Research Council Human Genetics Unit, U.K..

The JMJD1A protein is involved in a wide variety of other processes, including cancer, infertility, stem cell renewal, and sex determination of an embryo.

Reference article: The transcription factor GATA6 enables self - renewal of colon adenoma stem cells by repressing BMP gene expression Gavin Whissell, Elisa Montagni, Paola Martinelli, Xavier Hernando - Momblona, Marta Sevillano, Peter Jung, Carme Cortina, Alexandre Calon, Anna Abuli, Antoni Castells, Sergi Castellvi - Bel, Ana Silvina Nacht, Elena Sancho, Camille Stephan - Otto Attolini, Guillermo P. Vicent, Francisco X. Real and Eduard Batlle Nature Cell Biology (2014) Doi: 10.1038 / ncb2992

Hypoxia - induced Jagged2 promotes breast cancer metastasis and self - renewal of cancer stem - like cells

Next, because KLF4 is involved in self - renewal of stem cell, we also examined the effect of both miR - 7 and KLF4 on proliferation of CSCs by MTS assay and found that miR - 7 was capable of blocking the growth of CSCs, whereas ectopic expression of KLF4 significantly mitigated this effect of miR - 7 (Fig. 4C).

The scientists have discovered that the colon has a safety mechanism to prevent the self - renewal of adenoma stem cells (Image: Colorectal Cancer Lab, IRB Barcelona)

Phenotypic stability and unlimited self - renewal capacity of cell derived from pluripotent stem cells are essential properties for cell assay development for High Throughput Screening (HTS) strategies.

Michael Gershon, MD, Pathology & Cell Biology, will receive $ 2,193,710 over five years from the National Institute of Neurological Disorders and Stroke for «Microenvironment in Enteric Neuron Development» in a competitive renewal.

These cells have two main properties, unlimited self - renewal that can produce laboratory any desired number of undifferentiated cells and pluripotency, which provides access from the undifferentiated cells in all cell types of the human organism.

They believe this is because BMP signaling enhances cell renewal — a cell's ability to replicate — and keeps them in a pluripotent state, able to turn into any type of cell.

Lloyd Greene, PhD, Pathology & Cell Biology, will receive $ 1,956,935 over five years from the National Institute of Neurological Disorders and Stroke for «Neuron Death in Parkinson's Disease: The Role of Trib3» in a competitive renewal.

Both microRNA families have the connection to drug resistance as well as to cancer stem cells, sub-population of cancer cells that have self - renewal properties and the ability to give rise to new tumors that are more resistant to current therapy.

The software the Microsoft team then built generated billions of possible models that could explain stem cell self - renewal.

In parallel, the roles of symmetric and asymmetric cell divisions are investigated as a mechanism for governing stem cell self - renewal and differentiation during embryonic development and in the adult.

Synthetic peptide - acrylate surfaces for long - term self - renewal and cardiomyocyte differentiation of human embryonic stem cells.

Dr. Orkin's research focuses on the development and function of the blood system, the relationship between cancer and stem cells, and the mechanisms responsible for self - renewal of stem cells.