Effects
of Cholinesterase Inhibitors in Cognition on Parkinson's Disease Dementia: A Systematic Review and Meta - Analysis
Not exact matches
«For Alzheimer's patients, the standard
of care for symptomatic treatment remains
cholinesterase inhibitors, which are 25 years old at this point.
Other confounding factors including demographic data, cognitive status, vitality, mood, physical performance, and use
of medication (
cholinesterase inhibitors, calcium channel blockers [CCBs], diuretics, alpha blockers and anticholinergic drugs) were assessed.
Among persons using
cholinesterase inhibitors (AChEIs), risk
of pneumonia was increased in persons using also ACs (OR 1.53, 95 % CI 1.41 — 1.66).
The first,
cholinesterase inhibitors, act by inhibiting the breakdown
of the neurotransmitter, or neuron - to - neuron chemical messenger, acetylcholine.
Some people may experience «a robust benefit» from the combination
of memantine and a
cholinesterase inhibitor, he adds, while «some get none at all.»
Pairing memantine with a
cholinesterase inhibitor, a type
of drug that prevents the breakdown
of neurotransmitters involved in memory, has become a standard treatment for mild Alzheimer's disease, but this study «clearly flies in the face»
of that approach, says William Thies, PhD, the chief medical and scientific officer
of the Alzheimer's Association, a research and advocacy organization based in Chicago.
Tomatine acts as a
cholinesterase inhibitor that inhibits the removal
of acetylcholine from neuromuscular junctions.
When low
cholinesterase levels, a history
of exposure to
cholinesterase inhibitor products or typical symptoms make the diagnosis likely, the treatment is quick administration
of atropine and pralidoxime (2 - PAM, Protopam).
In dogs and cats that are showing typical signs
of insecticide or other
cholinesterase -
inhibitor poisoning, finding their
cholinesterase levels to be 25 - 35 % (or more) below normal confirms the diagnosis.