Sentences with phrase «of connexin»

In previous work, Dr. Ryosei Minoda, head of the Department of Otolaryngology at Kumamoto General Hospital, reported that hearing loss was restored by gene therapy to the inner ear of Connexin 30 deficient fetal mice.

Not exact matches

Meanwhile, on Tuesday the British telecommunications regulator, Ofcom, announced the names of the carriers that have qualified to take part in upcoming frequency auctions in that country: EE, Hutchison 3G UK (which trades as the Three network), Vodafone, Telefonica, Airspace and Connexin.

In research that has implications for diabetes and other metabolic diseases, an international study based at UT Southwestern Medical Center found that the protein connexin 43 (Cx43) forms cell - to - cell communication channels on the surface of emerging beige fat cells that amplify the signals from those few nerve fibers.

Here we used this approach to show that newly synthesized connexin43 was transported predominantly in 100 - to 150 - nanometer vesicles to the plasma membrane and incorporated at the periphery of existing gap junctions, whereas older connexins were removed from the center of the plaques into pleiomorphic vesicles of widely varying sizes.

The GJB6 gene encodes the CONNEXIN 30 protein, which is essential in hearing development, and a deficiency of the gene results in the second most common disease among cases of hereditary hearing loss that have no other disease in the inner ear.

The fact that Connexin 30 knockout mice had a higher number of grafted cells than normal mice, and that some of the grafted cells expressed CONNEXIN 30 is a very important finding when considering cell transplantation as a treatment for hereditary hearing loss caused by CONNEXIN defConnexin 30 knockout mice had a higher number of grafted cells than normal mice, and that some of the grafted cells expressed CONNEXIN 30 is a very important finding when considering cell transplantation as a treatment for hereditary hearing loss caused by CONNEXIN defCONNEXIN 30 is a very important finding when considering cell transplantation as a treatment for hereditary hearing loss caused by CONNEXIN defCONNEXIN deficiency.

They then transplanted progenitors of the inner ear cells into the inner ear of embryonic normal and Connexin 30 knockout mice using glass tubes with optimized tip sizes.

However, the Connexin 30 knockout mice had more grafted cells than the normal mice, and some of the grafted cells were found to express CONNConnexin 30 knockout mice had more grafted cells than the normal mice, and some of the grafted cells were found to express CONNEXINCONNEXIN 30.

Association between connexin 40 and potassium voltage-gated channel subfamily A member 5 expression in the atrial myocytes of patients with atrial fibrillation.

Connexins and Cadherin Crosstalk in the Pathogenesis of Prostate Cancer: DTIC Document.

hGDAsBMP also expressed connexin 43 (CX43), glutamate transporter 1 (GLT - 1), AKAP12 and glia - derived neurotrophic factor (GDNF), all of which are expressed in the astroglial lineage [23]--[25].

In 1997, he contributed to the development and validation of the OLA - PCR cystic fibrosis diagnostic panel commercialized by Applied Biosystems, and to the identification of the autosomal recessive neurosensory deafness connexin 26 gene.

Given that the gating profile when the UNC - 7S or L side is relatively negative (UNC - 9 positive) is similar to that of homotypic UNC - 7, and when UNC - 9 is relatively negative the limited gating response resembles UNC - 9 homotypic, we conclude that these members of the innexin family close the series gate on the negative side (this is the reverse of most, but not all, connexins [7]-RRB-.

Such rectifying behavior has been reported for some connexins, and has been shown to arise from the pairing of two hemichannels with different ion selectivities [34].