Sentences with phrase «of dicer»

Inhibition of Dicer or Ago2 expression revealed that small RNAs are involved in an immediate response to demethylation - induced transposon activation, while the deposition of repressive histone marks follows as a chronic response.

(2014) A variety of Dicer substrates in human and C.elegans.

Interestingly, suppression of Dicer activities is reported to result in promotion of epithelial - mesenchymal transistion and metastatic transformation of cancer cells.

Most importantly, miR - BART6 silences Dicer through multiple target sites located in the 3 «UTR of Dicer mRNA.

Recent studies revealed that loss of Dicer function to process Alu RNAs to small fragmented RNAs (Alu - siRNAs) underlie the AMD pathology.

This research suggests that therapy with an agent that increases levels of Dicer or specific miRNA expression could be beneficial to people with metabolic syndrome.

Not exact matches

Sharp knives, dicers, and graters can take the «labor» out of chopping & prepping veggies!

FoodSwing has spent in excess of $ 22 million automating a stainless steel fortress of cookers, tanks, dicers, pureeing machines, blending, liquefying and milling equipment — all just to prepare for the aseptic processing and filling operation.

Fusion Tech Dicer Wash Walls come with a number of design and sanitation features that add value to your facility and processing operation.

In plants and Caenorhabditis elegans, two distinct populations of small RNAs have been proposed to participate in RNAi: «Primary siRNAs» (derived from DICER nuclease - mediated cleavage of the original trigger) and «secondary siRNAs» [additional small RNAs whose synthesis requires an RNA - directed RNA polymerase (RdRP)-RSB-.

The pathologist of the Department of Pathology at the University Hospital of Bellvitge August Vidal explained that «this tumorigenic transformation depends on Dicer protein that could serve as a marker for the presence of tumor cells, or as a therapeutic target.»

According to the head of the research group of chemoresistance and Predictors of tumor response and stromal environment ICO - IDIBELL, Alberto Villanueva, «tumor exosomes contain certain proteins (Dicer, TRBP and Ago2) able to process microRNAs that can alter the around the tumor cells transforming them into tumoral cells.»

«It's good to build on our previous research on miRNA processing and Dicer in aging and find that a decline in Dicer may also play an important role in HIV lipodystrophy by dramatically changing the biology of fat and the tendency towards diabetes and metabolic syndrome,» says lead author C. Ronald Kahn, MD, Chief Academic Officer at Joslin Diabetes Center and the Mary K. Iacocca Professor of Medicine at Harvard Medical School.

On - going research of the Nishikura laboratory is to examine whether the Dicer promoting function of ADAR1 has any relevance to AMD.

The laboratory has shown that ADAR1 forms a complex with Dicer and promotes its catalytic activity, increasing Dicer cleavage of pre-miRNA, RISC assembly, and loading of miRNA.

For example, they discovered that ADAR1 forms a complex with Dicer to play a major role in the control of RNA interference mechanism.

Fareh, Yeom, Haagsma, Chauhan, Heo, Joo «TRBP ensures efficient Dicer processing of precursor microRNA in RNA - crowded environments» Nature Communications, (2016)

Re-evaluation of the roles of DROSHA, Export in 5, and DICER in microRNA biogenesis.

The length of the loop is at least 8 nucleotides long; there is no apparent maximum in loop length, even in organisms possessing only a single Dicer gene, contra (6), even though most taxa like vertebrates with single Dicer genes never show loop lengths greater than ~ 40 nucleotides.

We are exploring the roles for epigenetic enzymes, small non-coding RNAs, and DICER 1 in the initiation and maintenance of abnormal DNA methylation patterns in cancer.

I know it sounds like a late - night TV offer, with a vegetable dicer thrown in for free, but one of the most exciting areas of aging research is on the importance of the length of the tips of your chromosomes, called telomeres.

At the beginning of 2015, I decided to double down on all the self - care practices that fell by the wayside when I left the corporate world to become a professional slicer and dicer, by making one lifestyle change, one month at a time.

While fans will likely enjoy this tale of the conflicted Wolverine, the revengeful plot and frequent violent portrayals may give parents reason for concern about letting their kids see this slicer / dicer in action.

As long as we live in a capitalist society, people will seek advantage in making money within and outside of the rules, from the loaded - dicers in the alleyway to the megabanks behind the casinos.