Sentences with phrase «of ductal»

The prostate gland produces a glycoprotein by the cells of the ductal epithelium of the prostate, and is present in the blood serum of all males.

Results: Women who reported a clinical diagnosis of migraine had reduced risks of ductal carcinoma (OR, 0.67; 95 % CI, 0.54 - 0.82) and lobular carcinoma (OR, 0.68; 95 % CI, 0.52 - 0.90).

These were men with what's called PIN, which is like the prostate equivalent of ductal carcinoma in situ in the breast — an early stage of cancer.

The majority of breast cancers are made up of ductal carcinomas.

Mustafa R, De La Cruz L, Yoon - Flannery K, Fisher C, Tchou J, Czerniecki BJ: Management of ductal carcinoma in situ in women ≥ 65: A single institution experience Annals of Surgical Oncology 24 (2 Suppl 1): 82 - 83,2017.

(A) Normal case: negative Cyclin D1 - immunostaining in the ductal epithelial cells, (B) Benign case: few nuclei with weak expression of Cyclin D1 of ductal epithelial cell, and negative one in stromal cells, (C) IDC GII case: a strong positive expression of Cyclin D1 in invasive ductal epithelial cells and stroma, (D) IDC GIII case: moderate positive expression of Cyclin D1 in trabeculae malignant cells, and absent in the vesiculated polymorphic nuclei.

This interaction causes the myoepithelial cells — on the outer layer of the ductal structure — to contract, squeezing the luminal cells within.

Unlike the vast majority of pancreatic cancers (known as pancreatic adenocarcinomas) of the ductal part of the pancreas, pNET is not always deadly.

The organoids are entirely made up of ductal cells, eliminating the surrounding cell types that often contaminate samples from the pancreas.

Work by University of Manchester scientists has explored what allows some cases of Ductal Carcinoma in Situ (DCIS), a non-invasive form of breast cancer, to resist treatment and come back, as well as identifying a potential new target to improve the effectiveness of radiotherapy.

«Overdiagnosis» is likely only one to ten percent and is largely due to inclusion of ductal carcinoma in situ (DCIS).

The tissue, called the stroma, includes fat cells, or adipocytes, that provide padding; fibroblasts, which make the framework for tissue; pericytes in blood vessels, which are contractile cells that help regulate blood pressure; as well as myoepithelial cells comprising the outer layer of the ductal system through which milk flows.

Secretion of the hormones estrogen and progesterone set the stage for dramatic changes that take place in the breast during pregnancy: a massive proliferation of mammary epithelial cells, and the formation of thousands of ductal structures, which support milk production and transport during lactation.

All women, reduction surgery or no, have a finite quantity of ductal tissue in their breasts.

During puberty the breast begins to enlarge through the formation of adipose tissue and the branching and elongation of the ductal system.

Not exact matches

When yeast is ductal, causing shooting or stabbing pains within the breast, often topical treatments (those applied to the nipple area) do not penetrate well enough to affect the overgrowth of yeast in the ducts.

There some forms of breast cancer such as Paget's disease or ductal carcinoma that can cause bleeding from the nipples.

Growth and development of the mammary tissues begins at around weeks three and four of gestation, with specific ductal branching and lobular formation.

In the first half of pregnancy secretory differentiation (the differentiation of alveolar epithelial cells into milk - secreting cells), ductal branching and lobular formation of the breast (mammogenesis) occur.

This extra breast tissue is called accessory (or supernumerary) breast tissue and is not connected to the main ductal network of the breast.

Medical opinion also varies on how the kind of breast cancer Lee had, a noninvasive form called ductal carcinoma in situ, should be treated, but Lee is adamant about early mammograms and aggressive treatment.

A protein known as arginine methyltransferase 1 (PRMT1) may be a potential therapeutic target for pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer, and one of the most deadliest with a less than 10 percent, five - year survival rate.

The research team conducted a cross-sectional survey of women who underwent breast cancer surgery for invasive breast cancer or ductal carcinoma in situ at Women & Infants Hospital.

Kelvin Tsai at Taipei Medical University and Valerie Weaver at the University of California, San Francisco, decided to investigate the effect of chemotherapy on fibroblasts, a major component of the stroma in desmoplastic tumors such as breast cancer and pancreatic ductal adenocarcinoma.

It is mutated in 80 to 95 percent of pancreatic ductal adenocarcinomas (PDAC), the most frequent mutation in this cancer.

Ductal carcinoma in situ (DCIS) is a precursor of breast cancer where the cancerous cells are contained within the milk - making ducts.

Of 113 pancreatic ductal adenocarcinoma samples studied, 86 contained gemcitabine - inactivating bacteria.

Along with finding that the tumor suppressor protein SIRT6 is inactive in around 30 percent of cases of pancreatic ductal adenocarcinoma (PDAC), the team identified the precise pathway by which SIRT6 suppresses PDAC development, a mechanism different from the way it suppresses colorectal cancer.

The study, entitled COMET (Comparison of Operative to Medical Endocrine Therapy) for low - risk ductal carcinoma in situ, received funding through a $ 13.4 million, five - year award from the Patient - Centered Outcomes Research Institute (PCORI), an independent, nonprofit organization authorized by Congress in 2010 to support research that enlightens health care decisions.

Combining the results from all 100 patients showed that the findings were consistent across the three most common clinical subtypes of invasive ductal carcinoma.

To better understand the formation of metastases in pancreatic cancer, Christine Iacobuzio - Donahue, M.D., Ph.D., professor of pathology at Memorial Sloan Kettering Cancer Center, collected tumor samples from eight patients with the most common form of pancreatic cancer (pancreatic ductal adenocarcinoma) immediately after their deaths.

Recently, teaming up with co-investigator Associate Professor Dr. Rolf A. Brekken, they looked into its possible involvement in Pancreatic Ductal Adenocarcinoma (PDA), the most common form of pancreatic cancer, in a mouse model with an early onset aggressive form of tumor development.

Researchers at the Memorial Sloan Kettering Cancer Center found that while FDG PET / CT is valuable for systemic staging of stage III ductal breast cancer, it adds little to the systemic staging of ILC.

In a second group of experiments using human tissue from patients with pancreatic ductal adenocarcinoma, which accounts for more than 90 percent of pancreatic cancers, Zheng and his colleagues also tracked down a link between the abundance of Sema3D in those tissues and the progression of metastatic pancreatic cancer.

Pancreatic cancer — pancreatic ductal adenocarcinoma — is the most common tumor of the pancreas and has the worst prognosis.

Geschwind says the «extremely promising results» of the study make the encapsulated drug a good candidate for clinical trials, particularly for patients with pancreatic ductal adenocarcinoma.

Furthermore, the normal ductal cells that are able to develop into pancreatic cancer represent about 10 percent of the cells in the pancreas, complicating efforts to pinpoint the changes that occur as the tumor develops.

Pancreatic ductal adenocarcinoma is generally a fatal disease, with a five - year survival rate of less than 6 percent.

«The invasive structures we observed in our stiff matrices resemble the morphology of early - stage invasive ductal carcinoma.

With the current emphasis on genetic mutations in cancer, Longmore is careful to point out that 70 percent of invasive ductal breast cancers show DDR2.

Pancreatic ductal adenocarcinoma, the most common of pancreatic cancers, is extraordinarily lethal, with a 5 - year survival rate of just 6 percent.

Cancer of the pancreas (scientifically known as pancreatic ductal adenocarcinoma or PaCa) is one of the most deadly forms of the disease in humans.

The study focused on pancreatic ductal adenocarcinoma (PDA), a lethal form of cancer known to come with an influx of immune cells into tumors.

Surgery is the only potentially curative therapy for individuals with pancreatic ductal adenocarcinoma (PDA), the most common type of pancreatic cancer.

«Now we know that anastrozole is effective for treating hormone sensitive ductal carcinoma in situ, women will have a greater choice of treatments to suit their own previous medical histories and tolerability of medications.»

Pancreatic cancer, most frequently pancreatic ductal adenocarcinoma (PDAC), is the most lethal and aggressive of all cancers.

«The exciting research carried out by Dr Michael Allen and Professor Louise Jones makes significant steps forward in our understanding of the biology of DCIS (ductal carcinoma in situ) and its progression to invasive cancer.

A histology review typically classifies these as originating from the milk - passage (ductal) or milk - producing glands (lobules) of the breast.

PELOPS: Palbociclib and Endocrine Therapy for Lobular Breast Cancer Preoperative Study: A Randomized Phase II Study of Palbociclib with Endocrine Therapy versus Endocrine Therapy Alone for Invasive Lobular Carcinoma and Invasive Ductal Carcinoma

Stomnes, a postdoctoral researcher working with Philip Greenberg, M.D., and Sunil Hingorani, M.D., Ph.D., at the Fred Hutchinson Cancer Center at the University of Washington, has developed a mouse model of pancreatic ductal adenocarcinoma that is particularly good for studying this disease.