Sentences with phrase «of epistasis»

Epistatic effects are at their most dramatic in mixed breed dogs where, unlike a purebred dog, we have a relatively spotty (pun intended; coat color and patterning is a great example of epistasis) understanding of how the sequences from lots of contributing breeds will interact.

The concept of epistasis will also be introduced; a topic most students don't learn until AP Biology.

This discovery approach greatly enhances the future potential of epistasis analysis for systems biology, and can complement genome - wide association studies as a means of formulating hypotheses for targeted experimental work.

Detection of Epistasis for Flowering Time Using Bayesian Multilocus Estimation in a Barley MAGIC Population

Not exact matches

«This is important in the field because epistasis has been proposed as a source of «missing heritability,»» said the study's lead author, Joanna Thornycroft, a former graduate student at the Whitehead Institute for Biomedical Research, now at Wellcome Sanger Institute.

Schizophrenia researcher Daniel Weinberger of the National Institute of Mental Health in Bethesda agrees that the paper adds to evidence that epistasis — which has been shown in model organisms such as yeast but difficult to prove in humans — is «robust and ubiquitous.»

Such interactions, when the effect of a mutation is dependent on another, are known as epistasis.

Unequal duplicate epistasis - the normal allele at clf1 is a dominant suppressor of the recessive phenotype at clf2, and the normal allele at clf2 is a semidominant suppressor of the recessive phenotype at the clf1 locus.

Better understanding of these factors is a major area of interest in the lab, with some of the specific projects including tissue - specificity of cis - regulatory variants in the GTEx data set, immune response eQTLs where genetic variants contribute to inter-individual response to immunological stimuli, and haplotypic epistasis between regulatory and coding variants.

The search for epistasis by Andrew Brown Figuring out the role of each gene is a complex task.

No strong evidence was found for any epistasis between antigens driving population dynamics, or redundancy between functionally similar accessory ABTs, or age stratification of antigen profiles.

The striking differences observed in Themis1 - deficient rats of the BN and LEW genetic backgrounds suggest that an epistasis between Themis1 and other gene (s) controls Treg function.

In contrast with the BN rat strain, the disruption of the Themis1 gene in LEW rats does not lead to the spontaneous development of IBD or functional Treg defect, suggesting that an epistasis phenomenon in the BN genetic background controls these phenotypes.

This turning off or hiding the expression of another gene is called epistasis.