Sentences with phrase «of gene ontology»

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Among other things, the gene ontology has allowed researchers to efficiently ask, «What kind of genes are up - regulated under these conditions?»

The Orphanet Rare Disease Ontology (ORDO) is an open - access ontology developed from the Orphanet information system, enabling complex queries of a rare disorder and its epidemiological data (age of onset, prevalence, mode of inheritance) and gene - disorder functional relatiOntology (ORDO) is an open - access ontology developed from the Orphanet information system, enabling complex queries of a rare disorder and its epidemiological data (age of onset, prevalence, mode of inheritance) and gene - disorder functional relationtology developed from the Orphanet information system, enabling complex queries of a rare disorder and its epidemiological data (age of onset, prevalence, mode of inheritance) and gene - disorder functional relationships.

Dr.. He has initiated and led the development of several community - based ontologies, including Vaccine Ontology (VO), Ontology of Adverse Events (OAE), Ontology of Genes and Genomes (OGG), and Interaction Network Ontology (INO).

The principal component analysis revealed that aging explains ~ 16 % of protein expression variability and is associated with Gene Ontology terms transmembrane, integral / intrinsic membrane, endoplasmic reticulum and mitochondrion.

The Alliance brings together the efforts of the major National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)- funded Model Organism Database (MOD) groups, and the Gene Ontology (GO) Consortium, in a synergistic integration of expertly - curated information about the functioning of cellular systems.

Gene ontology analysis of the genes affected across several tissues (Supplementary Fig. 8) shows enrichment for genes in the extracellular region and genes involved in nucleosome and chromatin assembly and in protein — DNA complexes.

An approach for the identification of targets specific to bone metastasis using cancer genes interactome and gene ontology analysis

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence cgene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence cGene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Abbreviations: ACVR2A, activin A receptor type IIA; BMP, bone morphogenetic protein; BMPR, BMP receptor, type II; CNS, Central nervous system; DA, dopaminergic; DMEM / F12, Dulbecco's modified Eagle's medium nutrient mixture F - 12; E, embryonic day; GDF, growth differentiation factor; GO, gene ontology; KEGG, Kyoto encylopedia of genes and genomes; MAPK, Mitogen - activated protein kinase; mDA, midbrain dopaminergic; PD, Parkinson's disease; RIPA, radioimmunoprecipitation assay; SN, Substantia nigra; TGF - β, transforming growth factor - β; TH, tyrosine hydroxylase; VM, ventral midbrain / mesencephalon; Zeb2, Zinc finger E-box-binding homoeobox 2

Her scientific expertise lies in understanding the epigenetic basis of gene regulation during embryonic development and disease ontology.

Recent notable enhancements include user - directed submission of data, such as micropublication; genomic data curation and presentation, including additional genomes and JBrowse, respectively; new query tools, such as SimpleMine, Gene Enrichment Analysis; new data displays, such as the Person Lineage browser and the Summary of Ontology - based Annotations.

Many of the model organism databases (MODs) used by members of the GSA community — including FlyBase, WormBase, SGD, ZFIN, and MGI — have been supported by NIH's National Human Genome Research Institute (NHGRI), along with others supporting human and other research — such as OMIM, the Gene Ontology Consortium, and UniProt.

Gene ontology (GO) analysis of genes within 250 kb of a PORE sequence revealed enrichment in processes such as transcription regulator activity (p < 0.001), sex determination (p < 0.005), insulin receptor signaling (p < 0.001), development (p < 0.0005), and protein phosphorylation (p < 0.005).

We integrate functional genomic datasets with up - to - date gene and genome annotations, Gene Ontology and pathway annotations, gene orthologs, gene interactions, and a comprehensive set of miRNA - target predictions for human, mouse, zebrafish, and nematgene and genome annotations, Gene Ontology and pathway annotations, gene orthologs, gene interactions, and a comprehensive set of miRNA - target predictions for human, mouse, zebrafish, and nematGene Ontology and pathway annotations, gene orthologs, gene interactions, and a comprehensive set of miRNA - target predictions for human, mouse, zebrafish, and nematgene orthologs, gene interactions, and a comprehensive set of miRNA - target predictions for human, mouse, zebrafish, and nematgene interactions, and a comprehensive set of miRNA - target predictions for human, mouse, zebrafish, and nematode.

To better serve the broader research community, WormBase, with five other Model Organism Databases and The Gene Ontology project, have begun to collaborate formally as the Alliance of Genome Resources.

Analysis of overlaps between the merged ChIP and PORE lists, and resulting gene ontologies, were performed with WebGestalt.