Sentences with phrase «of mthfr»

People with varying degrees of MTHFR gene dysfunction have a much higher incidence of Alzheimer's, MS, ALS, Parkinson's and other such nervous system diseases and I wonder if there is an analogous canine physiological process.

I have just received results of MTHFR testing.

As a result, individuals with a genetic variation and low activity of the MTHFR enzyme may present with elevated homocysteine levels, which have been associated with inflammation, heart disease, pregnancy complications, and even miscarriages.

I have recently found out I have a double copy of the MTHFR gene as well and it has been overwhelming trying to understand it's implications and finding resources.

I chose to use this terminology after learning that I was a carrier of two copies of the MTHFR gene.

Coleen is author of the forthcoming book, «Thriving with MTHFR: A guide for the everyday mutant» and offers online trainings for both the Practitioner and the general public on the basics of MTHFR and Methylation.

If you have one of the MTHFR polymorphisms, the BH4 cycle may be affected and may impact how we make serotonin and dopamine.

It is believed that as much as 50 % of the population has some type of MTHFR mutation.

Dear Trudy, I am interested in lowering my anxiety levels and negative thoughts, I am 42 years old and have a single snip of MTHFR.

According to research, more than half the general population has some type of MTHFR mutation.

As the person ages, undiagnosed cases of MTHFR can become much worse, so it is important to get tested early and practice prevention.

He gives as an example the fact that nearly 50 % of people of Mexican heritage, and a large percentage of Caucasian and black Americans all have some kind of MTHFR mutation that results in neural tube defects, but people of Italian descent living in Southern Italy who have these same mutations do not have the problems with neural tube defects simply because their lifestyle and environment make up for their genes.

And you know, what people understand is that you - you may not have any copies of MTHFR, that you can have what I call a functional polymorphism where those pathways are not working because of too much oxidative stress, or environmental chemicals, or nutrient deficiencies.

So, I want to get your take on it, «cause, I mean, I see a lot of MTHFR stuff and I think it's — I think it's kind of overrated.

It is estimated that over half of the population has some form of MTHFR, which affects the way certain nutrients, like B vitamins, are (or are not) metabolized by the liver.

There are many different variants of the MTHFR gene.

Depending on which mutation of MTHFR you have, you may not be able to make or utilize certain nutrients.

Knowing which type of MTHFR will determine your risks and treatment.

Unfortunately, the discovery of a MTHFR mutation comes after trying unsuccessfully to get pregnant or having one or several miscarriages.

But I am unable to find further information within your database on the subject of MTHFR defects.

Currently, he researches, writes and presents worldwide on the topic of MTHFR and methylation defects.

I don't have the MTHFR C677T variants but has one variant of the MTHFR 1298C.

Problem is, nearly half (if not more) of U.S. women have some sort of MTHFR mutation, which means they can not properly digest folic acid.

I was extremely ill because of my MTHFR mutation.

We all have some form of MTHFR mutation except for my youngest son.

I sought the guidance of a MTHFR literate healthcare practitioner before beginning supplementation.

One key part of the MTHFR gene mutation is the inability to methylate folate correctly (especially in the synthetic form of folic acid).

The most common forms of MTHFR mutation involve various combinations of these genes being passed on from each parent:

I touched on the importance of the MTHFR enzyme briefly in my post about folic acid vs. folate and why I am careful to avoid synthetic folic acid in supplements and foods.

Individuals with low activity of the MTHFR enzyme may present with elevated homocysteine levels, which have been associated with inflammation and heart disease, birth defects, difficult pregnancies, and potentially an impaired ability to detoxify.

(2) The prevalence of the MTHFR A1298C associated 3 genotypes and A / C alleles in the recurrent miscarriage group did not differ significantly from the control.

C677T and A1298C mutation of MTHFR was tested in 148 cases with recurrent miscarriage and 82 normal controls.

Not exact matches

I go out of my way to avoid everyday toxins because I have the MTHFR gene which can lead to impaired detoxification.

For those who have MTHFR gene variants, supplemental folic acid has not been found to reduce the risk of miscarriage.

The likelihood of adverse events is higher is individuals who are MTHFR (methylenetetrahydrofolate reductase) positive and should be avoided by them.

I saw my maternal fetal medicine (MFM) specialist several weeks ago to discuss these matters and to review the results of some thrombotic risk tests that my MTHFR doctor had ordered.

This is the question on the lips of many a MTHFR sufferer.

If you have the MTHFR mutation, you'll need a methylated version of vitamin B6, such as Thorne's Basic B Complex.

A total of 150 women with a history of two or more recurrent miscarriages and 20 fertile control women with no history of pregnancy losses had buccal swabs taken for DNA analyses of 10 gene mutations [factor V G1691A, factor V H1299R (R2), factor V Y1702C, factor II prothrombin G20210A, factor XIII V34L, beta - fibrinogen -455 G > A, PAI - 1 4G / 5G, HPA1 a / b (L33P), MTHFR C677T, MTHFR A1298C].

CONCLUSIONS: Our study suggests that high folate intake may have adverse effects on fetal mouse development and that maternal MTHFR deficiency may improve or rescue some of the adverse outcomes.

This conversation covers all of that and so much more, including: metabolic typing, preconception nutrition, genetics, defining methylation, and the much talked about MTHFR mutation.

If you have MTHFR, put DOWN that glass of wine!

I recently learned that I have the MTHFR genetic mutation, which researcher Dr. Ben Lynch believes may be one of the causes of tongue and lip ties.

The MTHFR variant also helps with nutrient deficiency: It boosts production of the vitamin folate, important for pregnancy and fertility.

Examples of these include screening for cancer mutations and CpG methylation in hMLH1, p16, K - ras and B - raf, screening for other disease associated genes such as APOE, HFE, MTHFR, UBE3A and OCA2 associated with Angelman / Prader Willi syndrome.

Neither sex, smoking, BMI, alcohol consumption, APOE4 status nor MTHFR 677C > T polymorphism was associated with the rate of atrophy (P > 0.1 for all, adjusted for age).

In contrast, variants in the MTHFR gene have been associated with increased risk of neural tube defects and cardiovascular disease; however, 60 - 70 % of individuals in the general population have one of the two most common MTHFR gene polymorphisms.

The most extensively studied is MTHFR, which is also a central player in some forms of cancer.

To make matters more complicated, about 50 % of the population is estimated to have at least one mutation at the MTHFR gene and 10 % has two mutations, meaning they're less able to methylate B12 or convert cyanocobalamin to methylcobalamin.

Up to 50 % of Americans have an MTHFR gene defect of some type that impairs their ability to mthylate properly.