Sentences with phrase «of microvesicles»
Review of «Intercellular Transfer of Microvesicles from Young Mesenchymal Stromal Cells Rejuvenates Aged Murine Hematopoietic Stem Cells» from STEM CELLS by Stuart P. Atkinson
http://www.stemcellsportal.com/
Now, new research from the laboratory of Vaijayanti P. Kale (National Centre for Cell Science, Pune, Maharashtra, India) has described a fascinating new approach to return lost functionality to aged mouse HSCs: the transfer of microvesicles (MVs) containing positive regulators of autophagy derived from young mesenchymal stem cells (MSCs)[6].
Not exact matches
Besides messenger RNA, microvesicles also contain microRNA and proteins, providing information about both the transcriptional and regulatory environments of their parent cells.
Also covered will be techniques for analyzing exosomes, microvesicles, and apoptotic bodies in unprocessed samples, how imaging flow cytometry can be used to evaluate or reevaluate EV isolation techniques, and the advantages and disadvantages of using this method.
Comparing proteins within the microvesicles with the originating tumors showed that the vesicles also accurately reveal the protein content of the tumors, providing still more information about how tumors might respond to specific therapies, the researchers report.
Previous research has shown that many cells, including cancer cells, communicate directly with one another by emitting tiny bubbles of cellular material called microvesicles.
Previous research had analyzed the protein and lipid content of glioblastoma microvesicles.
«We kind of had this wild idea that because these tumor cells are just pouring [out microvesicles], maybe we can actually see it in the blood,» Breakefield says.
The rejuvenation of aged HSCs occurred thanks to the intercellular transfer of large membrane - derived extracellular vesicles known as microvesicles (MVs) carrying autophagy - related mRNAs
Isolation of Exosomes and Microvesicles from Cell Culture Systems to Study Prion Transmission.
Microvesicle - and exosome - mediated drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate cancer cells.
Bergersen LH, Morland C, Ormel L, Rinholm JE, Larsson M, Wold JF, Røe AT, Stranna A, Santello M, Bouvier D, Ottersen OP, Volterra A, Gundersen V (2012) Immunogold detection of L - glutamate and D - serine in small synaptic - like microvesicles in adult hippocampal astrocytes Cereb Cortex, 22 (7), 1690 - 7 PubMed 21914633