«By combining my laboratory's expertise in ovarian cancer biology and Dr. Xu's expertise in bioinformatics, we were able to uncover a potentially novel drug approach to treat ovarian cancer,» said co-senior author Analisa DiFeo, PhD, the Norma C. and Albert I. Geller Designated Professor
of Ovarian Cancer Research and assistant professor in the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine.
Kelly and accomplished master baker and cake decorator Buddy Valastro, from TLC's «Cake Boss,» recently joined forces at a fun event to bake lavishly decorated cakes in support
of The Ovarian Cancer Research...
Not exact matches
Electrolux and Kelly Ripa are proud to support the
Ovarian Cancer Research Fund whose mission is to fund research to find a method of early detection and ultimately a cure for Ovarian
Research Fund whose mission is to fund
research to find a method of early detection and ultimately a cure for Ovarian
research to find a method
of early detection and ultimately a cure for
Ovarian Cancer.
Research indicates that breastfeeding is beneficial for both you and your baby — you experience lower risk
of ovarian cancer, postpartum depression, breast
cancer and diabetes, while your baby receives all the good nutrients and also has a lower risk
of diseases like diabetes, obesity, asthma and lower respiratory infections.
Reams
of research have linked breastfeeding to scores
of benefits for both mom and baby: breast - fed babies aren't as likely to fall prey to obesity, ear infections or diabetes; breast - feeding moms benefit from a decreased risk
of breast and
ovarian cancer.
Recent
research demonstrates that lactating women have an earlier return to prepregnant weight, 41 delayed resumption
of ovulation with increased child spacing,42 - 44 improved bone remineralization postpartum45 with reduction in hip fractures in the postmenopausal period, 46 and reduced risk
of ovarian cancer47 and premenopausal breast
cancer.48
Research shows that women who have breastfed have lower chances
of getting
ovarian cancer and breast
cancer later in life.
Her work in protein
research at Hunter and her grandmother's recent diagnosis
of ovarian cancer sparked an interest in
cancer biology and immunology, but Rezende is eager to sample other fields.
The
research shows that ONA reduces the progression
of malignant
ovarian cancer tumors by interfering with the pro-tumor function
of myeloid cells.
This discovery is a result
of research on the effects
of ONA on a preclinical model
of epithelial
ovarian cancer (EOC) both in vivo and in vitro.
Funding for the study was provided by the National Institutes
of Health (P50 CA083638, R21 CA156224, 5P30 CA016520 - 36), the Marcus Foundation, the
Ovarian Cancer Immunotherapy Initiative, the Ludwig Institute for
Cancer Research at the University
of Lausanne, and the Ovacure Foundation.
«While the presence
of lymphocytes in tumors is often associated with better clinical outcomes, this
research adds clarity on the diversity
of T cells within the tumor environment and their influence on
ovarian cancer outcomes,» says first author Kunle Odunsi, MD, PhD, FRCOG, FACOG, Deputy Director, M. Steven Piver Professor and Chair
of Gynecologic Oncology, and Executive Director
of the Center for Immunotherapy at Roswell Park.
«What we've discovered will help clinicians to better treat women with
ovarian cancer,» says Dr. Ben Tsang, senior scientist at the Ottawa Hospital
Research Institute and professor at the University
of Ottawa.
«However, additional
research is needed to further evaluate the therapy for this type
of ovarian cancer.»
Cancer researcher Janet Sawicki of the Lankenau Institute for Medical Research in Pennsylvania, chemical engineer Robert Langer of MIT, and their colleagues are investigating biodegradable nanoparticles to deliver gene therapy for ovarian c
Cancer researcher Janet Sawicki
of the Lankenau Institute for Medical
Research in Pennsylvania, chemical engineer Robert Langer
of MIT, and their colleagues are investigating biodegradable nanoparticles to deliver gene therapy for
ovarian cancercancer.
Researchers using data collected by the
Ovarian Cancer Association Consortium have discovered uncommon variants in new regions of the genome that influence ovarian cancer risk, and will present their findings on April 6, 2014 at the American Association for Cancer Research Annual Meeting in San Die
Ovarian Cancer Association Consortium have discovered uncommon variants in new regions of the genome that influence ovarian cancer risk, and will present their findings on April 6, 2014 at the American Association for Cancer Research Annual Meeting in San Dieg
Cancer Association Consortium have discovered uncommon variants in new regions
of the genome that influence
ovarian cancer risk, and will present their findings on April 6, 2014 at the American Association for Cancer Research Annual Meeting in San Die
ovarian cancer risk, and will present their findings on April 6, 2014 at the American Association for Cancer Research Annual Meeting in San Dieg
cancer risk, and will present their findings on April 6, 2014 at the American Association for
Cancer Research Annual Meeting in San Dieg
Cancer Research Annual Meeting in San Diego, CA.
Acknowledging that «this is not a big study, in terms
of the overall number
of cases, for
ovarian cancer it's a very big study,» explains Annekatrin Lukanova of the International Agency for Cancer Research in Lyon, F
cancer it's a very big study,» explains Annekatrin Lukanova
of the International Agency for
Cancer Research in Lyon, F
Cancer Research in Lyon, France.
A Mayo Clinic
research team has found evidence suggesting that the controversial practice
of ovary removal in premenopausal women to prevent
ovarian cancer should be discontinued in women who are not at high risk
of cancer.
The lab
of co-author Dr. Robert Bast Jr., an expert in
ovarian cancer and vice president for translational
research at MD Anderson, inserted gel - bound carbon nanotubes into the ovaries
of rodents to mimic the accumulations that are expected for nanotubes linked to special antibodies that recognize tumor cells.
The
research team with international collaborators analysed more than 100 patient samples from
ovarian and other
cancer types to discover a distinct population
of cells found in some tumours.
Women
of reproductive age who have thyroid
cancer should be cautious about receiving radioactive iodine treatment, which affects their remaining egg supply — their
ovarian reserve — and may affect their fertility, new
research from Israel finds.
Now a team led by Lin Zhang, PhD,
research associate professor in the Department
of Obstetrics and Gynecology at the Perelman School
of Medicine at the University
of Pennsylvania, has mined those sequences to identify a non-protein-coding RNA whose expression is linked to
ovarian cancer.
«Dr. Moore's
research is ground - breaking in the area
of ovarian cancer, and it's all happening in his laboratory in the Knowledge District
of Providence.»
Nearly 20 percent
of women with
ovarian cancer do not undergo surgery, despite it being a standard part
of treatment recommendations, according to new
research from the Perelman School
of Medicine at the University
of Pennsylvania.
Dr. Narod, who is also a Tier 1 Canada
Research Chair in Breast
Cancer, recommends that doctors should consider adopting a standard model of care for all women diagnosed with advanced - stage ovarian c
Cancer, recommends that doctors should consider adopting a standard model
of care for all women diagnosed with advanced - stage
ovarian cancercancer:
Dr James Brenton,
Cancer Research UK's ovarian cancer expert, says: «A blood test to find women at risk of ovarian cancer is an exciting prospect, but this work still needs to be tested in women to see if it can save
Cancer Research UK's
ovarian cancer expert, says: «A blood test to find women at risk of ovarian cancer is an exciting prospect, but this work still needs to be tested in women to see if it can save
cancer expert, says: «A blood test to find women at risk
of ovarian cancer is an exciting prospect, but this work still needs to be tested in women to see if it can save
cancer is an exciting prospect, but this work still needs to be tested in women to see if it can save lives.
New
research from George Vasmatzis, Ph.D.,
of the Department
of Laboratory Medicine and Pathology at Mayo Clinic, finds liquid biopsies from blood tests and DNA sequencing can detect a return
of ovarian cancer long before a tumor reappears.
Up to half
of women with advanced - stage
ovarian cancer might be cured, compared to the current 20 per cent survival rate, argues Dr. Steven Narod, senior scientist at Women's College
Research Institute, who calls for a new standard
of treatment for women with late - stage
ovarian cancer.
«There is currently no national screening programme for
ovarian cancer, as
research to date has been unable to provide enough evidence that any one method would improve early detection
of tumours.
Dr. Vasmatzis»
research on the «Quantification
of Somatic Chromosomal Rearrangements in Circulating Cell - free DNA From
Ovarian Cancers» is published in the July 20 edition
of Scientific Reports.
The results come from analysis
of one arm
of the UK Collaborative Trial
of Ovarian Cancer Screening (UKCTOCS), the world's largest ovarian cancer screening trial, led by UCL and funded by the Medical Research Council, Cancer Research UK, Department of Health and The Eve
Ovarian Cancer Screening (UKCTOCS), the world's largest ovarian cancer screening trial, led by UCL and funded by the Medical Research Council, Cancer Research UK, Department of Health and The Eve A
Cancer Screening (UKCTOCS), the world's largest
ovarian cancer screening trial, led by UCL and funded by the Medical Research Council, Cancer Research UK, Department of Health and The Eve
ovarian cancer screening trial, led by UCL and funded by the Medical Research Council, Cancer Research UK, Department of Health and The Eve A
cancer screening trial, led by UCL and funded by the Medical
Research Council,
Cancer Research UK, Department of Health and The Eve A
Cancer Research UK, Department
of Health and The Eve Appeal.
Research like this gives scientists and doctors a clearer view
of what is driving this form
of ovarian cancer and has the potential to lead to new treatments.
«For decades, women have been treated with a combination
of treatment options, resulting in poor prognosis for most women with advanced - stage
ovarian cancer, but there are many survivors as well,» said Dr. Narod, senior scientist at Women's College
Research Institute.
In lab experiments, the
research team used cell lines derived from 40 patient tumour samples to identify that CD151 contributes to the survival
of cells
of high - grade serous
ovarian cancer origin.
The
research was the first to comprehensively examine the six major flavonoid subclasses present in the normal diet with
ovarian cancer risk, and the first to investigate the impact
of polymers and anthocyanins.
«What we did in this paper is engineer our sensor to be about 15 times better than a previous version, and then compared it against a blood biomarker in a mouse model
of ovarian cancer to show that we could beat it,» says Sangeeta Bhatia, the John and Dorothy Wilson Professor of Health Sciences and Technology and Electrical Engineering and Computer Science, a member of MIT's Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and Science, and the senior author of the
cancer to show that we could beat it,» says Sangeeta Bhatia, the John and Dorothy Wilson Professor
of Health Sciences and Technology and Electrical Engineering and Computer Science, a member
of MIT's Koch Institute for Integrative
Cancer Research and Institute for Medical Engineering and Science, and the senior author of the
Cancer Research and Institute for Medical Engineering and Science, and the senior author
of the study.
The
research reveals that women who consume foods containing flavonols and flavanones (both subclasses
of dietary flavonoids) significantly decrease their risk
of developing epithelial
ovarian cancer, the fifth - leading cause
of cancer death among women.
«Scientists track
ovarian cancers to site
of origin: Fallopian tubes: Small study offers proof
of concept, support for wider
research.»
The collaborative
research team — which included experts in gynecological
cancer, genomics, pathology and computational biology — performed a comprehensive genetic analysis
of ovarian and endometrial CSs.
In earlier
research, Barbolina discovered that a fractalkine receptor — a protein found on the cell surface — is expressed in the majority
of ovarian cancer cases.
Blocking a protein found on the surface
of ovarian cancer cells could prevent or reduce the spread
of the disease to other organs, according to new
research at the University
of Illinois at Chicago.
Although this
research was conducted on
ovarian cancer cells, the ground - breaking results are applicable to a wider range
of cancers.
Longer term, they want to quickly diagnose additional
cancer types, including
ovarian and pancreatic
cancers, which are fast - spreading and require early detection for a patient to survive, says Goda, who was recently appointed as a chemistry professor at the University
of Tokyo but will continue his
research with U.C.L.A..
While previous
research had shown some effectiveness
of this molecule in a mouse model
of ovarian cancer, that benefit was limited by the immunosuppressive environment within tumors, particularly the presence
of regulatory T cells (Tregs).
Many
of these genes are usually switched off in adults, but previous
research has shown that in many
cancers — including prostate,
ovarian, and brain
cancer, melanoma, and leukemia — HOX genes are switched back on, helping the
cancer cells to proliferate and survive.
Led by Ludwig Lausanne investigator Alexandre Harari and George Coukos, director
of the Ludwig Institute for
Cancer Research, Lausanne, the study shows that
ovarian tumors harbor highly reactive killer T cells — which kill infected and cancerous cells — and demonstrates how they can be identified and selectively grown for use in personalized, cell - based immunotherapies.
Now, however, a team led by Merajver and another headed by Ellen Solomon and John Trowsdale
of the Imperial
Cancer Research Fund in London say that they have both found damaged copies of BRCA1 in ovarian tumours from women with no family history of cancer (Nature Genetics, vol 9, p 343 and
Cancer Research Fund in London say that they have both found damaged copies
of BRCA1 in
ovarian tumours from women with no family history
of cancer (Nature Genetics, vol 9, p 343 and
cancer (Nature Genetics, vol 9, p 343 and 439).
Women with Stage III
ovarian cancer given a combination of intravenous and intraperitoneal chemotherapy following surgical debulking of tumor had a median survival nearly 16 months longer than women who received IV chemotherapy alone, according to a study published conducted by the Gynecologic Oncology Group (GOG), a National Cancer Institute - supported research network, in the January 5, 2006 issue of the New England Journal of Med
cancer given a combination
of intravenous and intraperitoneal chemotherapy following surgical debulking
of tumor had a median survival nearly 16 months longer than women who received IV chemotherapy alone, according to a study published conducted by the Gynecologic Oncology Group (GOG), a National
Cancer Institute - supported research network, in the January 5, 2006 issue of the New England Journal of Med
Cancer Institute - supported
research network, in the January 5, 2006 issue
of the New England Journal
of Medicine.
Professor Paul Pharoah, professor
of cancer epidemiology at the Cancer Research UK Cambridge Institute, said: «Our work has found a valuable piece of the puzzle behind ovarian cancer and we hope that our work could eventually form the basis of a genetic test to identify women at greatest
cancer epidemiology at the
Cancer Research UK Cambridge Institute, said: «Our work has found a valuable piece of the puzzle behind ovarian cancer and we hope that our work could eventually form the basis of a genetic test to identify women at greatest
Cancer Research UK Cambridge Institute, said: «Our work has found a valuable piece
of the puzzle behind
ovarian cancer and we hope that our work could eventually form the basis of a genetic test to identify women at greatest
cancer and we hope that our work could eventually form the basis
of a genetic test to identify women at greatest risk.
I was honored to receive the Mentor Award from the American Congress
of Obstetricians and Gynecologists in 2012 and the Foundation for Women's
Cancer's Excellence in
Ovarian Cancer Research Prize in 2013.