He has published over 175 articles in this field
of pharmacogenetics.
He is head
of the Pharmacogenetics Core Laboratory AKC (part of BO&O) and he is responsible for Point - of - Care testing at the Erasmus MC.
Ron H.N. van Schaik, PhD is a registered European Clinical Chemist (2003) andProfessor
of Pharmacogenetics (2008).
Prof. Dr. Ron van Schaik, PhD is a registered European specialist Laboratory medicine (2003) and a Full Professor
of Pharmacogenetics (2013).
The Sections aims are, to promote the exchange
of pharmacogenetic knowledge by organization of symposia and workshops in the field of pharmacogenetics and genomics, to evaluate the clinical impact of pharmacogenetics, to assist with the development and maintenance of drug - related pharmacogenetic databases and to create a population based biobank to conduct translational research in clinical pharmacogenomics.
Her primary interests are in treatment and pharmacogenetics of childhood leukemia and clinical implementation
of pharmacogenetic testing.
Similarly an accusation of deliberate murder by poisoning by a care home was revealed to have been likely to have naturally arisen as a result
of a pharmacogenetic cause resulting in the victim being unable to excrete the prescribed tranquiliser in question.
Not exact matches
The study
of drug interactions and ultimately
pharmacogenetics then took off.
Using a
pharmacogenetics approach, the researchers selectively switched off specific groups
of brain cells — called neural ensembles — that react to select cues signaling either reward availability or reward omission.
Amàlia Lafuente is a professor
of pharmacology specializing in
pharmacogenetics and vice chair
of the Department
of Pathological Anatomy, Pharmacology, and Microbiology in the School
of Medicine at the University
of Barcelona in Spain.
He also actively participates in several major international consortium, such as International Warfarin
Pharmacogenetic Consortium, International Clopidogrel
Pharmacogenetic Consortium, Clinical
Pharmacogenetics Implementation Consortium and worked with a group
of experts to develop clinical use
of HLA - B * 5801 and allopurinol.
«With the inauguration
of the Institute for Personalized Medicine, we have reasserted our early leadership in the science
of tailoring therapy to individuals, an approach that in some ways began at Hershey with the observations around
pharmacogenetics by our founding chair
of pharmacology, Elliot Vesell, more than 40 years ago,» said Daniel Notterman, vice dean for research and graduate studies.
We worked with Brian Gage and Deepak Voora on the
pharmacogenetics of warfarin (coumadin), a widely - used oral anticoagulant.
The lovely violin plots at right show the mean GERP scores (a measure
of conservation) for included versus excluded variants in the newborn screening (NBS), age - related macular degeneration (ARMD), and
pharmacogenetics (PGx) genes examined.
His major achievement is in the
pharmacogenetic study
of warfarin dose requirements, which resulted in the identification the SNP associated with warfarin dose.
He is Director
of the International (IFCC) Reference Center for
Pharmacogenetics and he leads the Unit Research & Development
of the Dept. Clinical Chemistry.
Professor;
Pharmacogenetics group, Department
of Physiology and Pharmacology, Karolinska Universitet, Stockholm, Sweden
•
Pharmacogenetics The unit offers population screening for a number
of validated polymorphisms with
pharmacogenetic implications, associated with positive or negative responses to therapeutic agents.
Since her initial published findings in a 2001 issue
of the journal
Pharmacogenetics, Mealey discovered 12 other dog breeds, including Long - Haired Whippets and Silken Windhounds, are susceptible.
He has been at the forefront
of developing and applying new technologies for neural circuit manipulation, such as optogenetics and
pharmacogenetics, to the study
of emotional behaviors such as fear, anxiety and aggression, in both mice and fruit flies.
We also perform
pharmacogenetics testing to help physicians choose the right drug at the right time for treatment
of childhood epilepsy and other disorders.
The National Institutes
of Health funded the study through a grant to the
Pharmacogenetics of Anticancer Agents Research Group.
One
of Dr. Innocentis exemplary achievements is the elucidation
of the genetic basis
of severe neutropenia in cancer patients treated with irinotecan, a poster child for
pharmacogenetic.
Dr. Innocenti sits on the editorial board
of Journal
of Clinical Oncology,
Pharmacogenetics and Genomics, Therapeutic Drug Monitoring, Current Drug Metabolism, and others.
He joined UNC in January 2011 after twelve years
of research in cancer
pharmacogenetics at the University
of Chicago.
Phase I safety, pharmacokinetics, and
pharmacogenetics study
of the antituberculosis drug PA - 824 with concomitant lopinavir - ritonavir, efavirenz, or rifampin.
Pharmacogenetics is the study
of how different groups
of people respond to drugs, based on their genetic makeup.
- A
Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing; Stephen Kimmel, MD, MSCE, Perelman School
of Medicine at the University
of Pennsylvania.
Molecular actions and clinical
pharmacogenetics of lithium therapy.
Today, the Golden Helix Foundation and the Section
of Pharmacogenomics and
Pharmacogenetics of International Union
of Basic and Clinical Pharmacology (IUPHAR) have entered into a collaborative agreement to foster their cooperation and to advance basic and clinical research in pharmacogenomics, its clinical translation and educational and learning activities.
A
pharmacogenetic «restriction -
of - function» approach reveals evidence for anxiolytic - like actions mediated by α5 - containing GABAA receptors in mice.
A
Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing; Stephen Kimmel, MD, MSCE, Perelman School
of Medicine at the University
of Pennsylvania.
This session will explore some common drugs and the genetics
of their metabolism; will also overview
pharmacogenetic nomenclature, and lastly, will review guidelines that support
pharmacogenetic testing.
Understanding individual variability in the effects
of antipsychotic drugs -
Pharmacogenetics to epigenetics
3 - 4 pm: Stephen Miller (Poster presentation)- The I - PICC Study: Protocol for a point -
of - care randomized controlled trial
of statin
pharmacogenetics in a learning healthcare system
Dr. Relling is part
of NIH's Pharmacogenomics Research Network and co-founder
of CPIC, the Clinical
Pharmacogenetics Implementation Consortium.
He is a member
of the Scientific Advisory Board
of the Clinical
Pharmacogenetic Implementation Consortium (CPIC) and a member
of the CPIC informatics committee and has participated in guideline creation and review for that group.
Residents
of nursing homes that performed
pharmacogenetic testing had reductions in moderate to severe pain compared with those residing in nursing homes that did not do this type
of personalized...
Mia Wadelius is Professor
of Clinical
Pharmacogenetics at Uppsala University and Senior Physician
of Clinical Pharmacology at Akademiska Sjukhuset.
184/6: 15 Assessing the clinical impact
of ethnicity - specific
pharmacogenetic allele variation in over 100,000 patients with biobank - linked electronic medical records.
He participates in national and international advisory committees on
pharmacogenetics, a.o. IFCC Task Force Pharmacogenetics (Chair), IATDMCT Pharmacogenetics Committee (chair), Dutch Task Force Pharmacogenetics (NVKC; chair), Dutch Committee on Molecular Biological Diagnostics (CMBD; chair), IUPHAR working group Pharmacogenetics (member), European Pharmacogenetics Research Network (Steering Committee), European Society for Personalized Medicine (EUSPM; treasurer), European Society for Pharmacogenetics and Theranostics (ESPT; Chair Scientific & Clinical Implementation Division), AACC Personalized Medicine Division (founding member) and the Pharmacogenetics Working Group of the European Medici
pharmacogenetics, a.o. IFCC Task Force
Pharmacogenetics (Chair), IATDMCT Pharmacogenetics Committee (chair), Dutch Task Force Pharmacogenetics (NVKC; chair), Dutch Committee on Molecular Biological Diagnostics (CMBD; chair), IUPHAR working group Pharmacogenetics (member), European Pharmacogenetics Research Network (Steering Committee), European Society for Personalized Medicine (EUSPM; treasurer), European Society for Pharmacogenetics and Theranostics (ESPT; Chair Scientific & Clinical Implementation Division), AACC Personalized Medicine Division (founding member) and the Pharmacogenetics Working Group of the European Medici
Pharmacogenetics (Chair), IATDMCT
Pharmacogenetics Committee (chair), Dutch Task Force Pharmacogenetics (NVKC; chair), Dutch Committee on Molecular Biological Diagnostics (CMBD; chair), IUPHAR working group Pharmacogenetics (member), European Pharmacogenetics Research Network (Steering Committee), European Society for Personalized Medicine (EUSPM; treasurer), European Society for Pharmacogenetics and Theranostics (ESPT; Chair Scientific & Clinical Implementation Division), AACC Personalized Medicine Division (founding member) and the Pharmacogenetics Working Group of the European Medici
Pharmacogenetics Committee (chair), Dutch Task Force
Pharmacogenetics (NVKC; chair), Dutch Committee on Molecular Biological Diagnostics (CMBD; chair), IUPHAR working group Pharmacogenetics (member), European Pharmacogenetics Research Network (Steering Committee), European Society for Personalized Medicine (EUSPM; treasurer), European Society for Pharmacogenetics and Theranostics (ESPT; Chair Scientific & Clinical Implementation Division), AACC Personalized Medicine Division (founding member) and the Pharmacogenetics Working Group of the European Medici
Pharmacogenetics (NVKC; chair), Dutch Committee on Molecular Biological Diagnostics (CMBD; chair), IUPHAR working group
Pharmacogenetics (member), European Pharmacogenetics Research Network (Steering Committee), European Society for Personalized Medicine (EUSPM; treasurer), European Society for Pharmacogenetics and Theranostics (ESPT; Chair Scientific & Clinical Implementation Division), AACC Personalized Medicine Division (founding member) and the Pharmacogenetics Working Group of the European Medici
Pharmacogenetics (member), European
Pharmacogenetics Research Network (Steering Committee), European Society for Personalized Medicine (EUSPM; treasurer), European Society for Pharmacogenetics and Theranostics (ESPT; Chair Scientific & Clinical Implementation Division), AACC Personalized Medicine Division (founding member) and the Pharmacogenetics Working Group of the European Medici
Pharmacogenetics Research Network (Steering Committee), European Society for Personalized Medicine (EUSPM; treasurer), European Society for
Pharmacogenetics and Theranostics (ESPT; Chair Scientific & Clinical Implementation Division), AACC Personalized Medicine Division (founding member) and the Pharmacogenetics Working Group of the European Medici
Pharmacogenetics and Theranostics (ESPT; Chair Scientific & Clinical Implementation Division), AACC Personalized Medicine Division (founding member) and the
Pharmacogenetics Working Group of the European Medici
Pharmacogenetics Working Group
of the European Medicine Agency (EMA).
These investigators use a clever
pharmacogenetic approach, combining cell - specific expression
of the porcine liver esterase (PLE) with delivery
of MK801 linked to 4 - hydroxy -3-nitrobenzyl carbamate through a carboxymethylpropyl ester group.
Our
pharmacogenetics testing helps on the medication side while working on removal from Medications and the application
of lifestyle strategies.
Pharmacogenetics: This branch is related to the clinical testing
of genetic variation that primarily gives rise to the differing response to human - made drugs.
Pharmacogenetics is a novel technology, making its way out
of academia into the general medical community and is considered «disruptive medicine.»