«We found that while pH alone resulted in the generation
of STAP cells, the use of a low pH solution containing ATP, dramatically increased the efficacy of this conversion.
In the latest twist in the story
of STAP cells, a new kind of stem cell described in two Nature papers in January, a scientist is live - blogging his latest attempt to generate the cells.
On 5 March, RIKEN released more detailed procedures for the creation
of the STAP cells.
Not exact matches
It's your comment on the noise
of the velcro that will help us... because so many time my children fell asleep in the ergo and I discreetly unlocked the
staps to let them sleep on...
«And as the scrutiny has grown, several
of the collaborating researchers have confirmed that they have not yet produced
STAP [stimulus - triggered acquisition
of pluripotency] cells either.»
She «is willing to retract a paper concluding that so - called
STAP stem cells can form a wide variety
of tissues, but does not intend to retract the paper describing how to make those stem cells.»
«It would be naive to think that only the letter [the second paper] can be retracted and that the [methods] article will remain with the
STAP cell narrative overall having any legitimacy,» stem cell researcher Paul Knoepfler
of the University
of California, Davis told ScienceInsider in an e-mail.
► In April, we reported that stem cell scientist Haruko Obokata (the lead author
of the two
STAP — stimulus - triggered acquisition
of pluripotency — papers in Nature) was found guilty
of research misconduct by a RIKEN investigating committee.
Rat regret... a shortage
of physician - scientists... congressional meddling... the latest on
STAP... Working Life
► On Wednesday at ScienceInsider, Dennis Normile reported that stem cell scientist Haruko Obokata (lead author
of the two
STAP — stimulus - triggered acquisition
of pluripotency — papers in Nature) «has agreed to retract the two Nature papers that reported her work.»
Scientist Kenneth Ka - Ho Lee, who has been trying to reproduce
STAP cells and has been regularly blogging about his progress, has given up, writing «I don't think
STAP cells exist and it will be a waste
of manpower and research funding to carry on with this experiment any further.»
► This afternoon, Normile reported at ScienceInsider that top administrator's at RIKEN, Japan's network
of laboratories, «will voluntarily return 1 to 3 months
of their salaries to atone for their responsibility for the
STAP stem cell fiasco.»
► You may remember «last year's sensational claims surrounding stimulus - triggered acquisition
of pluripotency (
STAP) cells, the supposedly powerful stem cells derived using a remarkably simple recipe,» as Gretchen Vogel described it in a piece published Wednesday.
More cautious researchers would have realized they were on the wrong track, says Rudolf Jaenisch, a stem cell researcher at the Massachusetts Institute
of Technology in Cambridge whose lab spent 2 months trying to make
STAP cells and contributed data to the new paper.
Makoto Asashima, executive director
of the Japan Society for the Promotion
of Science, told ScienceInsider that the manual «is not a response to the
STAP problem.»
Now, as the 21st century gains ground in an ancient industry,
Stap and his family have installed a robotic milking system that allows each
of Twin Brook Creamery's 200 cows to choose when and how often she wants to saunter into the milking parlor, where she enjoys a meal and gets milked — all without the need for human supervision.
The 30 - year - old was widely celebrated when she and colleagues published two papers in Nature describing a new and surprisingly simple way
of creating stem cells, which the researchers dubbed stimulus - triggered acquisition
of pluripotency (
STAP) cells.
He added that to the best
of their knowledge, no outside group has reported success in generating
STAP cells.
Obokata worked under Vacanti for several years, starting in 2008, and developed the
STAP technique based on some
of his earlier work.
«The mission
of the investigating committee is to determine whether or not there has been misconduct; whether
STAP cells exist is something for the scientific community to determine,» said committee chair Shunsuke Ishii, a RIKEN molecular geneticist, at the press conference, which lasted a marathon 4 hours.
RIKEN launched an investigation after claims
of image manipulation and plagiarism surfaced regarding a research article and a letter published online in Nature on 29 January that described a new, simple way
of creating stem cells called
STAP, for stimulus - triggered acquisition
of pluripotency.
And as the scrutiny has grown, several
of the collaborating researchers have confirmed that they have not yet produced
STAP cells either.
Separately, Kenneth Ka - Ho Lee, an embryologist and stem cell researcher at the Chinese University
of Hong Kong who live - blogged about his futile attempts to reproduce
STAP cells, today published all the details
of his efforts online at F1000Research.
► Last Friday, Dennis Normile reported on a bizarre turn in the
STAP (stimulus - triggered acquisition
of pluripotency) stem cell affair.
Shunsuke Ishii, the chair
of the RIKEN investigating committee that recently found stem cell scientist Haruko Obokata (first author on the Nature papers reporting the
STAP results) guilty
of research misconduct, is himself under investigation for research misconduct.
Further studies on
STAP - 2 will provide new insights into cancer physiology and support the development
of anticancer therapies,» says Tadashi Matsuda.
The research coming under fire reported the discovery
of a potentially revolutionary process called stimulus - triggered acquisition
of pluripotency (
STAP), in which exposing adult cells to a stress such as acid or pressure prompts them to behave like cells in early embryos, which can become any cell type in the body.
The committee's final report (in Japanese), released today, is the latest blow against a surprisingly simple method for creating stem cells, known as
STAP (stimulus - triggered acquisition
of pluripotency), published in a Nature article and an accompanying letter online on 29 January by Obokata and colleagues at RIKEN CDB, along with other institutions in Japan and at Harvard Medical School in Boston.
Yamanaka was referring to a recent string
of public apologies by stem cell scientists in Japan, triggered by two high - profile papers published earlier this year that claim to have found an alternate way to reprogram adult cells into embryolike ones — called
STAP (stimulus - triggered acquisition
of pluripotency) cells.
In his most recent online poll, 53 %
of respondents indicated that they were «convinced» or «close to convinced that [
STAP cells] are not real.»
The researchers called the process «stimulus - triggered acquisition
of pluripotency,» or
STAP.
STAP, or stimulus - triggered acquisition
of pluripotency, is the name given to an extremely easy way
of deriving stem cells, which can theoretically develop into any
of a body's tissues.
The top administrators
of RIKEN, Japan's national network
of research laboratories, will voluntarily return 1 to 3 months
of their salaries to atone for their responsibility for the
STAP stem cell fiasco.
They described what they dubbed stimulus - triggered acquisition
of pluripotency (
STAP) cells in a research article and a research letter published online in Nature on 29 January.
To take responsibility for the
STAP problem, RIKEN President Ryoji Noyori will return 3 months» worth
of his salary to the institute.
«I don't really hear from almost anyone who fully believes in
STAP cells anymore,» wrote stem cell researcher Paul Knoepfler
of the University
of California, Davis, School
of Medicine wrote in a 25 March blog post.
But lately he had been immersed in controversy over two papers, published in Nature in January, that claimed a simple method
of creating embryonic - like cells, called stimulus - triggered acquisition
of pluripotency (
STAP).
Two papers claiming that stressing the body's cell could produce embryonic - like stem cells, a process called stimulus - triggered acquisition
of pluripotency (
STAP), were heralded when published in Nature in January but thrashed soon after when problematic images and figures were soon found.
«In recent months, our lab decided to re-explore the utility
of a low pH solution containing ATP in generating
STAP cells,» Vacanti writes in the revised protocol.
Soon after that, the lead author on the paper laying out the fundamental
STAP technology, Charles Vacanti
of the Brigham and Women's Hospital in Boston, Massachusetts, released his own, quite different, list
of tips for reproducing
STAP.
Called
STAP cells, the new stem cells can change into more types
of cells than other lab - made stem cells.
STAP (stimulus - triggered acquisition
of pluripotency) cells were thought to be engineered stem cells created when hematopoietic stem cells from the spleens
of newborn mice were exposed to an acid environment, triggering their conversion from multipotent somatic cells to pluripotent - like stem cells.
What makes Dr. Obokata's newly discovered cells, called «Stimulus - Triggered Acquisition
of Pluripotency,» or
STAP cells, so remarkable is that they are created, not by genetic manipulation, but through exposure to a more acidic environment.
I just used the new one today, the
stap holder on side broke while at the airport, one
of the tassels to zip with apparently fell off.
in an olive, navy and purple colorblock dress, with T -
stap sandals and a glittery clutch at the premiere
of Before We Go in L.A.
do you attach a stud to each
of the horizontal
staps??
Greatest game i have ever played on pc thew online battles are imenss when some one is trying to
stap u with a knife on the game u can't help but jump back or bend your back trying to avode the knife very good in deed a must have for all FPS fans but pust have a good pc i recmned making your own or dell or suthing not pcworld that con u out by a hell
of lot brill game.