Sentences with phrase «of a high fat diet by»

The scientists were able to reverse the effect of a high fat diet by artificially increasing production of the GnT - 4a enzyme which restored GLUT1 levels.

● Override the harmful effects of a high fat diet by preventing obesity and liver disease.

Not exact matches

Many people could raise their general level of wellness at the same time they enhance their appearance and self - image, by doing two things — drastically reducing or eliminating the intake of junk food, refined sugar, and other carbohydrates, saturated fats, alcohol, and nicotine; and adding more healthful foods to their diets including vegetable proteins, whole - grain cereals and bread, raw vegetables and fruits, and high fiber foods.

As someone who has struggled with my weight my entire life, I also benefit from a high fat, moderate protein, low carb diet, so this is a great way for me to start off my day with the high level of satiety provided by a fat - infused cup of spicy tea.

Blood sugar instability is often a result of a diet marked by high carb, low protein / fat / fiber intake.

It is intended to complement solid foods in the baby «s diet and provide a transition to a nonformula diet because a higher percentage of the energy is supplied by protein and carbohydrate instead of fat.

A study in this issue of JCI Insight demonstrates that mice lacking the proinflammatory signaling molecule TAK1 are protected from obesity and insulin resistance induced by a high fat diet.

Our study shows that after that early programming state, after weaning, and after the lactation period, when we introduced a new type of diet it changed the epigenome in a way that actually affects metabolism and potentially will reduce some of the damage caused by an early - life high - fat exposure,» Pan says.

By combining each mouse's genome, phenome, proteome and metabolome, the scientists were able to identify a particular gene, located on their chromosome 2, and whose presence plays an important role in the development of type 2 diabetes «The mice with a high - fat diet are more or less likely to develop diabetes depending on whether this gene is active or not,» said Evan Williams, LISP PhD student and the article's co-first author.

Now, a high - fat, low - carbohydrate version of the ketogenic diet has been shown to slow glioblastoma tumors by cutting back on the energy supply they need to thrive, said Brent Reynolds, Ph.D., a professor in the Lillian S. Wells Department of Neurosurgery.

Eating a diet higher in saturated fat, a type of fat found commonly in foods such as fatty beef and cheese, was linked to more aggressive prostate cancer, a study by University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators has found.

To mimic this obesogenic environment, the teams led by Mara Dierssen at CRG and Rafael Maldonado at UPF offered mice the option of a high - fat «cafeteria» diet or a mixture of chopped - up commercial chocolate bars alongside their regular lab chow, before carrying out a detailed analysis of the animals» activity and feeding behaviour.

In mice that are given a high - fat diet, an increased production of the enzyme DPP4 * by the liver promotes an increase in body fat, the development of fatty liver disease and insulin resistance.

The prevention of dilated cardiomyopathy in a mouse model by feeding a high - fat diet signals an advance in the understanding of the mechanisms involved in heart disease and has implications for the future development of treatments for this condition.

Jonscher believes the antioxidant may work by impacting pathways critical to the early onset of diseases associated with maternal obesity, high fat diets and inflammation.

The article, «Systemic effects of a high saturated fat diet in grizzly bears (Ursus arctos horribilis)» by Danielle Rivet, Lynne Nelson, Chantal Vella, Heiko Jansen, and Charles Robbins was published today in the Canadian Journal of Zoology.

«We did not do it using a genetic strain of obese mice, but mice that became obese the way that people do, by eating a high - fat, high - sugar diet.»

«Bears not bothered by diet high in saturated fats: Grizzlies show no clinical signs of disease following short - term consumption of saturated fats but scientists question long - term health.»

Rivet recommends that the «availability of human refuse in natural areas inhabited by bears should be eliminated for bear, as well as human, health and safety,» adding that, «diets of captive [bears] should be carefully selected to avoid high saturated [fat] content.»

Published in the August 2015 issue of Nature Medicine, the new findings show that a small molecule called N1 - methylnicotinamide prevents metabolic complications caused by a high - fat diet.

The upshot of the study, another indictment of the so - called Western diet (high in saturated fats, sugar and red meat), reveals how the metabolites produced by the bacteria in the stomach chemically communicate with cells, including cells far beyond the colon, to dictate gene expression and health in its host.

The article «A gestational diet high in fat soluble vitamins alters expression of genes in 1 brain pathways and reduces sucrose preference, but not food intake, in Wistar male rat offspring» by Sanchez - Hernandez et al. was published in the journal Applied Physiology, Nutrition, and Metabolism.

They found that by adding it to the high - fat diet, the compound would decrease the level of obesity in the animals and would increase their ability to deal with increased blood glucose levels.

By injecting daily a low dose of a large spectrum antibiotic they were able to reverse the effects of high fat diet on the microbiota composition.

HCC can be caused by several factors including a high - fat diet, and this form of liver cancer is increasing due to rising obesity.

The Paleolithic diet is characterised by a high intake of protein and unsaturated fats and has a low glycemic index.

In a small phase I and II clinical trial, Johns Hopkins researchers and colleagues elsewhere found that the high - fat, low - carbohydrate ketogenic diet was a safe and effective treatment option for the majority of adults experiencing a relatively rare, often fatal and always severe form of epilepsy marked by prolonged seizures that require medically induced comas to prevent them from further damaging the body and the brain.

Like all mammal poop, the samples were dominated by bacteria of two phyla: Firmicutes, thought to play a role in the absorption of dietary fats, and Bacteroidetes, associated with high - fiber diets.

The high - fat diet without the flavanones increased the levels of cell - damage markers called thiobarbituric acid reactive substances (TBARS) by 80 percent in the blood and 57 percent in the liver compared to mice on a standard diet.

To explore that question, a team led by Cornell University biomedical engineer Claudia Fischbach first showed that female mice that were obese, because of genetics or a high - fat diet, had more fibrous mammary fat pads with straighter collagen fibers than those seen in lean mice (see image).

Transplanted hearts lasted in four groups of mice as follows: • 21 days: mice with hyperlipidemia caused by a genetic mutation of apolipoprotein E (ApoE) placed on a high - fat diet • 51 days: healthy mice placed on a high - fat diet leading to hyperlipidemia • 61 days: mice with hyperlipidemia caused by a genetic mutation of ApoE on a lower - fat diet • More than 100 days: healthy mice placed on a lower - fat diet

«A lot of the diseases that do come about today or have been linked with high - fat diets or things like that have been referred to by some researchers as «diseases of affluence.»

In other research, a knockout of the gene that encodes one type of lncRNA in mice conferred some resistance to obesity caused by a high - fat diet.

The circumstances of ecstasy use increase the risk as the drug is popular in crowded clubs where people can easily become dehydrated by dancing and alcohol use; and a high - fat diet appears to raise blood levels of fatty acids which can impede body temperature regulation.

The researchers found enriching the diet of mice with the fermentable fiber inulin prevented metabolic syndrome that is induced by a high - fat diet, and they identified specifically how this occurs in the body.

«We found that under conditions of obesity and a high - fat diet, the cells that typically strengthen our immune system by killing viruses and pathogens instead increase blood sugar.

Our findings are in agreement with a recently published study by Oskarsson et al. (2015) in which Tg mice injected through the tail vein with in vitro — generated aggregates from synthetic peptides containing the sequence of IAPP developed a higher percentage of IAPP aggregates in the pancreas than did untreated controls when subjected to a high - fat diet.

Among their experiments, the researchers studied beta cell signaling in mice that were modified to lack expression of the proteins and experienced insulin resistance by being placed on a high - fat diet, or aging, or becoming pregnant.

Dr. Verdin further found that prolonged intake of a high - fat diet, even in normal mice, can itself reduce the activity of the enzyme produced by SIRT3 — an enzyme his laboratory originally discovered.

The URMC team, led by Michael Zuscik, Ph.D., associate professor of Orthopaedics in the Center for Musculoskeletal Research (CMSR), Robert Mooney, Ph.D., professor of Pathology and Laboratory Medicine, and Steven Gill, Ph.D., associate professor of Microbiology and Immunology, fed mice a high fat diet akin to a Western «cheeseburger and milkshake» diet.

Researchers at Vanderbilt University have inhibited weight gain, insulin resistance and various other negative health effects of a high - fat diet in mice by modifying bacteria to produce a therapeutic compound in the gut.

To understand how obesity occurs and how it may be treated requires an understanding of the genes that regulate body weight and how their function is influenced by environmental factors such as diets high in calories and dietary fat.

«In our model, stress conditions, such as a genetic variant or insulin resistance or a high - fat diet, lead to increased availability of the tribbles protein by as yet poorly understood mechanisms,» says Dr. Kulkarni, who is also an Assistant Professor of Medicine at Harvard Medical School.

Conclusions: Metabolic inflammation and NFкB - mediated neuroinflammatory responses in the NAc contribute to the expression of anxiodepressive behavior and heightened food cravings caused by a diet high in saturated fat and sugar.

In the past, Western - type diets have been made by adding high levels of fat and cholesterol to grain - based chow diets.

(A — F) Mutant mice of the indicated genotypes that were fed a high - fat diet for 6 weeks were treated for the last 5 weeks with control or ApoC - III ASO, and pooled plasma lipoproteins from fasted animals were analyzed by size - exclusion FPLC (n = 3 / pool).

Germline loss of Tmem18 in mice resulted in increased body weight, which was exacerbated by high fat diet and driven by increased food intake.

And when you consider all the added sugars found in most commercial brands of this condiment, it's no wonder it got such a bad rep.. However, if you can find a brand without any added sugars or make it by yourself with tomatoes, vinegar, salt and spices, ketchup can become a real healthful gem in your diet — it's very low in calories (there are only 15 calories in one tablespoon, compared to 100 calories in one tablespoon of mayonnaise), contains practically no fat and it's especially high in lycopene, one of the most important cancer - fighting phytonutrients found in tomatoes and other red fruits and vegetables.

Back in the 70's, when the nation was threatened by the rapidly increasing number of deaths from cardiovascular diseases and science had just uncovered that a diet high in saturated fats and cholesterol poses a serious threat for cardiovascular health, health officials issued dietary advice that entailed consuming less fat.

Endomorphs are characterized by round bodies, a high percentage of body fat, and a slow metabolism which results in weight gain even when diverging only a little from a clean food diet.