A single dose
of a human antibody called ZIKV - 117 can protect mice from death after Zika infection — and shield mouse fetuses from the virus's damaging effects, researchers report November 7 in Nature.
A single dose
of a human antibody called ZIKV - 117 can shield mouse fetuses from the virus's damaging effects, researchers report online November 7 in Nature.
Not exact matches
In
humans, scientists know a lot about the cells involved in immediate
antibody production,
called plasmablasts, but less about the separate group
of cells responsible for the «storage / research for the future» functions,
called memory B cells.
Anthony Fauci, director
of the National Institute
of Allergy and Infectious Diseases,
called the new work a «significant advance,» noting in a statement that it «opens the way to producing [monoclonal
antibodies] that potentially could be used diagnostically or therapeutically» for the flu as well as other infectious diseases such as hepatitis C and the
human immunodeficiency virus (HIV), which can lead to full - blown AIDS.
So -
called cancer immunotherapy — which is the treatment
of tumors by the use
of antibodies — has been established and used very successfully in
human medicine for about 20 years.
Around the same time that transgenic mice began to be used to produce
human antibodies, scientists also started employing a genomic technology
called phage display to build massive libraries
of human antibody genes that could be screened quickly.»
They fused mouse B cells —
antibody - producing cells
of the immune system — with
human myeloma (also known as B cell cancer) cell lines in a new technique
called hybridoma technology.
Colin Barnstable, DPhil (M Club) Chair, Neural and Behavioral Sciences «Production
of monocolonal
antibodies to group A erythrocytes, HLA and other
human call surface antigens — new tools for genetic analysis» Cell, 1978 2,020 citations, Web
of Science, April 1, 2017