Sentences with phrase «of a particular gene with»

The researchers tag unusual spellings of a particular gene with short strands of marker DNA linked to a reporter molecule that readily shows up in the microscope.

Not exact matches

With respect to antibiotic resistance, this novelty can be induced and we can trace the novelty to particular mutations arising absent gene transfer; i.e. the genes which give rise the resistance were not present prior to the mutation, they are new sequences and not simply the activation of dormant genes.

To quote Ayala and Kiger's textbook, Modern Genetics: «There is no way of knowing whether a given gene will mutate in a particular cell or in a particular generation,» because the mutations «are unoriented with respect to adaptation.»

If Chad and others argue that naturalistic evolution must be dismissed because we don't know exactly what happened with gene mutation and transmission frequencies during particular periods of rapid change, then how can we accept a replacement argument in which we don't even know what happens at all?

It was a perfect storm of the right combination of capsaicin genes colliding with some stress on those particular plants that produced an abnormally high amount of capsaicin.

By comparing Bhut Jolokia's RAPD markers with the reference markers, is was possible to determine which species» genes are part of this particular pepper variety.

Other research shows that ADHD children with a particular gene variation have thinner tissue in the area of the brain that's associated with attention.

Women with precancer or cancer were most likely to have particular versions of the viral gene E7, which researchers are now interested in targeting.

The team found that humans are equipped with tiny differences in a particular regulator of gene activity, dubbed HARE5, that when introduced into a mouse embryo, led to a 12 % bigger brain than in the embryos treated with the HARE5 sequence from chimpanzees.

By combining each mouse's genome, phenome, proteome and metabolome, the scientists were able to identify a particular gene, located on their chromosome 2, and whose presence plays an important role in the development of type 2 diabetes «The mice with a high - fat diet are more or less likely to develop diabetes depending on whether this gene is active or not,» said Evan Williams, LISP PhD student and the article's co-first author.

They started with pairs of fat yellow mice known to scientists as agouti mice, so called because they carry a particular gene — the agouti gene — that in addition to making the rodents ravenous and yellow renders them prone to cancer and diabetes.

As a graduate student at the University of California, San Francisco, he heard molecular biologist Cynthia Kenyon describe how worms with a mutation in a particular gene had double the lifespan of those without it.

Because the vast majority of genes are encoded with exactly the same code, this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact there are many variant codes; thus, the canonical genetic code is not universal.

When produced in excess during times of adversity, these particular miRNAs trigger epigenetic changes, which alter gene activity to cope with these environmental hardships.

Within a single tumor exists such an astonishingly varied population of cells, each with its own combination of normal and abnormal genes, that at least some cells nearly always have a way to survive any particular attack.

siRNAs are very small molecules that carry genetic information to cells, but unlike DNA that can turn genes on, siRNA interferes with the production of particular proteins and can turn cancer genes off.

To figure out what's really happening within an organism — or within a particular organ or cell — researchers are linking the genome with large - scale data about the output of those genes at specific times, in specific places, in response to specific environmental pressures.

Having just one copy of a particular variant of a gene called CREBRF is associated with a 1.5 increase in BMI.

Many conditions, including various cancers, heart attacks, lupus, and depression, likely arise when a particular mix of genes collides with something in the environment, such as nicotine or a fatty diet.

The aim is to introduce into the shuttle a viral vector loaded with the gene that the cells of these patients lack, with a particular focus on targeting neurons.

Individuals who had a particular variation in a specific gene (platelet derived growth factor D; PDGFD) had a markedly increased risk of adrenal suppression, both in the children with asthma and adults with COPD.

In many cases, the activity of particular genes was tied to a single genetic variant, with strong differences in frequency between European and African populations.

Their cooperative behavior and the division of labor confer superiority on that group, with that particular gene, over other groups.

Their research, published in PLOS ONE, focused on one particular gene — TRIM29 — selected from a pool of 100 genes with regulatory patterns specific to normal breast tissue, to prove the link between breast - specific genes and the pathology of cancer.

Similarly, someone who inherits the version of a particular gene that's associated with obesity will be more likely to wind up fat than someone who inherits a normal version, but that tendency can be affected by environmental factors such as how much fattening food is available.

Previous work had shown that two variations in the COX - 2 gene, with either a guanine (G) or a cytosine (C) molecule at a particular spot in the gene's DNA sequence, lead to different levels of COX - 2 protein.

Even with the advent of DNA sequencing and genetic identification, this was generally done with one particular ribosomal gene.

Laurent Keller at the University of Lausanne in Switzerland and Kenneth Ross at the University of Georgia, Athens, were scanning the genes of various populations of fire ants (Solenopsis invicta) when they noticed something strange: Queen ants who had their own colonies carried two copies of the dominant variety of a particular gene — they were homozygous for the variety, that is — while those who shared a nest with other queens were heterozygous, carrying only one copy.

For example, some people have a particular variant of the ADH1B gene that causes an amino acid change in this enzyme, which leads to faster enzyme activity so individuals with this variant metabolize alcohol more rapidly which means that acetaldehyde levels are temporarily increased.

Of particular interest was that four of the 10 sites most strongly linked to the AOSI scores were located near genes linked to Prader - Willi syndrome, a genetic disorder that shares some behavioral symptoms with autisOf particular interest was that four of the 10 sites most strongly linked to the AOSI scores were located near genes linked to Prader - Willi syndrome, a genetic disorder that shares some behavioral symptoms with autisof the 10 sites most strongly linked to the AOSI scores were located near genes linked to Prader - Willi syndrome, a genetic disorder that shares some behavioral symptoms with autism.

As part of the International Visible Trait Genetics Consortium, he and his colleagues examined the DNA of five groups of people to see whether any particular variants of a gene were associated with each trait.

Analyzing large numbers of cells, each with slight differences in their DNA, for their ability to carry out a behavior or survive a drug treatment can reveal the importance of particular genes, or sections of genes, in those abilities.

Patients with a particular inherited variation in the gene IFITM3 were more than twice as likely to develop severe, life - threatening flu symptoms as those who carried the protective version of the gene.

Frequently, the term cloning is misleadingly used to refer to the identification of the chromosomal location of a gene associated with a particular phenotype of interest.

The study identified several other potential colitis genes, he added, and this particular one's effect on the barrier cells» energy requirements suggests a new category of mutations with the potential to cause IBD.

Steve: And we've also discovered, because we now have some actual NeandertalDNA to work with, that they did have this particular gene, FOXP2 gene, that is correlated with our ability to speak, not that I'm a good example of [that] right at the moment.

They sent soil samples for DNA testing, looking for matches with particular genes known to be found in microbes and fungi; they tried to stimulate microbial growth on a wide variety of substances and then count the cells produced; and they used highly sensitive radiorespiration activity assays, which involve feeding the soil microorganisms a food source which has been labelled with radioactive carbon, which can then be used to detect if the microorganisms are active.

In June, he and his colleague Thaddeus Stappenbeck argued in Nature that all mouse studies should use littermate controls: When studying the activity of a particular gene, breed mice with and without that gene by starting with heterozygous parents.

A region inside the csd gene in particular represents a hot - spot with a high evolutionary rate that, together with certain amino acid mutations, decisively contributes to the formation of new csd alleles in the flanking regions.

Interestingly, performance on the Eyes Test in males was not associated with genes in this particular region of chromosome 3.

Most interestingly, the scientists found that individuals with a particular combination of mutations in both genes had five times the risk of developing asthma than those without.

Specifically, the findings explain how a particular gene — called fkbp5 — is involved in a phenomenon known as «fear extinction,» through which animals and humans disassociate with fearful memories of a traumatic experience, such as war, assault or a natural disaster.

The research team had previously identified a section of DNA adjacent to the HoxD gene cluster, which formed a particular 3D structure in order to interact with and activate certain Hox genes.

In particular, the research identified several genes regulated by methylation in the egg that are involved in cell adhesion and migration — both vital properties for cells of the developing placenta in establishing connections with maternal tissues to support embryo development.

From this we compared the genomic distributions of our hotspots to the genomic distribution of various features associated with genome evolution and genes that participate in particular biological processes.

These studies have given us a better understanding of the genes that influence the development of these cells, and in particular, to characterize the differences between subsets of Vα14i NKT cells with distinct functional properties.

The researchers also hope to use gene sequencing technology to compare the brains of those who have died of Alzheimer's with those of people who died without neurological diseases, in the hope of finding DNA sequences of particular microbes in the diseased brains.

«This data allows classification of all human protein - coding genes into those coding for house - hold functions (present in all cells) and those that are tissue - specific genes with highly specialized expression in particular organs and tissues, such as kidney, liver, brain, heart, pancreas.

The current work shows that changes in the genetic code of a particular gene can control epigenetic marks at different genes, implying that a gene's genetic code can affect whether other genes are turned on and off, which makes it important to understand the function of all genes involved, not just the one with the so - called misspelling.

For example, a particular gene variant in the promoter region of the IL10 gene is associated with a 40 to 60 % increased risk of developing active tuberculosis among Europeans and Americans [75].