Scientists have identified a basic pathologic process underlying Alzheimer's development that involves the formation
of abnormal protein deposits in the brain known as beta - amyloid plaques, but they still aren't entirely sure what causes this to happen.
But this is the first study to show how lifestyle factors directly influence levels
of abnormal protein deposits in the brain that have been long tied to Alzheimer's disease.
Not exact matches
People with the transthyretin amyloidosis have mutations in the DNA
of the transthyretin gene, which causes
abnormal buildup and
deposits of a transport
protein called transthyretin in nerve and heart cells.
This turned out to be a normal
protein in the cells
of organisms throughout the animal kingdom — but in brains infected with scrapie and related diseases it turns up in both a normal, soluble form and an
abnormal, insoluble form which accumulates in
deposits that eventually kill the cells.
Studies in mice specially bred to have features
of the disease found that DHA reduces beta - amyloid plaques,
abnormal protein deposits in the brain that are a hallmark
of Alzheimer's, although a clinical trial
of DHA showed no impact on people with mild to moderate Alzheimer's disease.
Familial amyloid polyneuropathy is characterized by
abnormal protein deposits that can affect the nerves and other functions
of the body.
However, autoimmune disease, genetics, obesity, chronic pancreatitis, certain medications and
abnormal protein deposits in the pancreas can play a major role in the development
of the disease.
Autoimmune disease, genetics, obesity, chronic pancreatitis, certain medications and
abnormal protein deposits in the pancreas can play a major role in the development
of the disease.