Sentences with phrase «of abnormal proteins»

LM22A - 4 treatment reduced the accumulation of abnormal proteins in the striatum and cortex — brain regions affected in Huntington's disease.

«If we can better understand what leads to accumulations of these abnormal proteins in the eye, that will hopefully also give us insight into how the brain works.»

In most cases, CTE is thought to be caused by repeated blows to the head, which damage brain tissue and lead to a buildup of an abnormal protein called tau, according to the CTE Center.

This leads to a buildup of an abnormal protein called tau, which affects portions of the brain and results in Alzheimer's - like symptoms, including memory loss, mood swings, and rage.

But this is the first study to show how lifestyle factors directly influence levels of abnormal protein deposits in the brain that have been long tied to Alzheimer's disease.

During the mitosis stage of budding yeast's division, aggregates of abnormal protein are tethered to well - anchored mitochondria in the mother cell.

In thyroid cancer in dogs caused by parafocllicular cells can cause diarrhea resulting from the production of abnormal proteins in the C - cells.

Several factors have been implicated in Alzheimer's, including the build - up of an abnormal protein called beta amyloid, fibrous tangles in the brain involving abnormal forms of a protein called tau, and — most recently — an association between the disease and a gene called ApoE.

In a proof - of - concept study, published in the journal Neurobiology of Disease, the drug nortriptyline, which has been used to treat depression and nerve pain, stopped the growth of abnormal proteins that can build up in the brain and lead to the development of the disease.

Collier then began testing rats with the tricyclic antidepressant nortriptyline and found that it indeed was able to decrease the amount of abnormal protein that can build up in the brain.

Some of these mutations may alter genes so that they code for small stretches of abnormal proteins that the immune system sees as foreign proteins, or antigens.

In cancer cells, the drugs produce a substantial increase in the display of abnormal proteins on the cells» surface.

Howard Hughes Medical Institute researchers have provided the first detailed look at the core structure of the abnormal protein filaments found in at least 20 devastating diseases, ranging from...

Deep inside the brains of people with dementia and Lou Gehrig's disease, globs of abnormal protein gum up the inner workings of brain cells — dooming them to an early death.

The exact cause of these diseases is not entirely known, although environmental triggers, genetic factors and the presence of abnormal protein deposits known as Lewy Bodies are known to play an important role in upsetting regular brain function.

Because several human neurodegenerative diseases are known to be linked to an accumulation of abnormal protein aggregates, basic science aimed to understand how cells remove cellular garbage is elementary for designing strategies for a potential prevention or cure of such disorders.

By combining pieces of different genes, fusion genes can lead to production of abnormal proteins that disrupt cell function.

Growing evidence has shown that dementia in older adults is usually due to multiple causes, including Alzheimer's disease, which is characterized by a buildup of abnormal proteins in the brain, as well as vascular dementia, which results from brain tissue not receiving enough blood due to blockages and leaks in the brain's blood vessels.

The problem with making blood stem cells proliferate outside the body is that the artificial growth gives rise to an accumulation of abnormal proteins in a part of the cell called the endoplasmic reticulum, ER.

«How nerve cells are damaged by accumulation of abnormal proteins.»

The gene UPF3B, for example, helps cells rid themselves of abnormal proteins.