Sentences with phrase «of abnormal tissue»

Treatment of mammary tumors involves surgical excision of all abnormal tissue with submission of the tissue for histopathology (testing to determine tissue health and presence of malignancy).

Much more advanced diagnostics may include computed tomography (CT scan) and / or magnetic resonance imaging (MRI), each of which provides a more sensitive assessment of the extent of abnormal tissue.

When a focal cancerous mass is removed, the surgeon tries to also remove a small amount of normal tissue around the entire mass of abnormal tissue, in order to achieve what are called «clean surgical margins.»

The disease is characterized by a narrowing (stenosis) caused by a ridge or ring of abnormal tissue growth that inhibits blood flow from the heart to the aorta.

Though rare, SAS also occurs in human children, and one treatment option is surgery to remove the ridge or ring of abnormal tissue below the aortic valve.

A biopsy of the abnormal tissue, sent for microscopic pathological examination, will confirm the diagnosis.

Sterile pyogranuloma syndrome: a disease of the deeper layers of the skin characterized by formation of abnormal tissues, with no infectious organisims involved.

Not exact matches

A lesion is any abnormal tissue, which could represent a polyp, an ulcer, or a miriad of other conditions other than coeliac disease.

Despite these signs, a genetic error has occurred during the fertilization process, causing a placenta and abnormal tissue to grow instead of an embryo.

In an interview, the Glasgow - based neurologist described how he had examined sections of brain tissue in a retired rugby player and found abnormal proteins associated with head injuries and dementia.

Although these spots themselves are harmless, if some of the spots are bigger than a 50 cent coin, then it could be due to Neurofibromatosis (NF), which is a genetic disorder of the nervous system that causes abnormal cell growth of nerve tissues or benign tumours to form on the nerves anywhere in the body at any time.

They're harmless, but do keep an eye on the size and quantity of these spots, since having six or more that are larger than a quarter may be a sign of neurofibromatosis (a genetic disorder that causes abnormal cell growth of the nerve tissue).

Scar tissue also does not have any hair follicles associated with it, which is another factor that gives it an abnormal appearance from the rest of the skin.

Also limiting the use of therapeutic stem cells to date, self - renewal, a quality so vital to a fast - growing fetus, can also be a source of cancer risk when haphazard, unlimited cell multiplication results in the abnormal tissue growth seen in tumors.

The researchers found that HAND2 methylation is already increased in premalignant endometrial lesions (cancer - prone, abnormal - looking tissue) compared to normal endometrium, and that a high level of methylation predicted a poor response to progesterone treatment (which stops the growth of some pre-cancerous endometrial lesions).

They do more than watch the camera, they are able to remove polyps — abnormal growths — both to prevent precancerous polyps from becoming malignant and to examine the tissue for signs of cancer.

They found a two - way association between IBD, notably Crohn's disease, and neoplastic lesions, or abnormal tissue growth, of the uterine cervix.

«Importantly, this knowledge will help us better understand healthy tissue homeostasis and the wide range of diseases that involve abnormal tissue mechanics, especially cancer.»

An advanced stage, called proliferative diabetic retinopathy, occurs when abnormal blood vessels grow near the retina, the light - sensitive tissue at the back of the eye.

The device can treat either form of age - related macular degeneration: the dry stage, where the delicate tissues of the macula become thinned and slowly lose function, or the less common wet stage that's caused by the growth of abnormal blood vessels behind the macula.

The abnormal tissue has to penetrate and grow in other areas of the body.

The other five were conducted in mice; they found that, after being exposed to the blood of young mice, old mice had less abnormal thickening of their heart, grew more nervous tissue, and saw improved cognitive function, among other changes.

The researchers say their findings also shed new light on how kidney disease leads to an abnormal thickening of heart muscle tissue called hypertrophy, which is a leading cause of death in people with kidney disease caused by high blood pressure, diabetes, and other illnesses.

Abnormal and uncontrolled production of this class of proteins, known as transcription factors, allow for cells to bypass growth control mechanisms and to develop characteristics necessary for invading surrounding tissues.

Constraining NF - kB can at times lead to tissue damage and a process of abnormal regeneration of that tissue that can foster cancer.

These pathologies fall broadly into four categories: coagulopathy, where abnormal blood clotting is caused; haemorrhaging, where bleeding occurs; neurotoxicity, which damages the nervous system causing paralysis, and cytotoxicity, where the bite causes death of cells and destruction of tissue.

Recent studies have deciphered a microRNA «signature» associated with cancer: The levels of certain microRNAs in tissue from different cancers are abnormal — usually more abundant — compared with the tissues from healthy people.

The test requires removing cerebrospinal fluid (CSF) from patients by means of a spinal tap, putting samples into a bath of normally shaped prion proteins, and agitating the solution to encourage any abnormal prion «seeds» in the tissue to latch onto the regular proteins.

In humans, this kind of abnormal change in the nature of a tissue is called «metaplasia,» and is associated with chronic inflammation.

They found that tissue with high levels of epileptic electrical activity was low in lactate and had higher levels of creatine, phosphocreatine and choline, suggestive of abnormal metabolism.

A more expensive injection form of the drug was discovered by Kopchick a decade ago, and it has since been approved by the FDA to treat individuals with acromegaly, a condition in which there is too much growth hormone in adults, resulting in abnormal growth of body tissues, especially hands, feet, and face.

It will allow physicians to precisely identify small regions of abnormal brain tissue in early - stage epilepsy patients that can't be detected today using current technology.

In most cases, CTE is thought to be caused by repeated blows to the head, which damage brain tissue and lead to a buildup of an abnormal protein called tau, according to the CTE Center.

These splice sites instruct the genetic machinery to build abnormal dystrophin molecules, but once the gene is successfully edited it expresses a much - improved dystrophin protein product, enhancing the function of the muscle tissue.

But after treatment, tissue analysis showed that only 45 per cent of the abnormal axons were still there.

In many cases, they select regions of brain tissue that — in an MRI image, for example — appear to have an abnormal structure.

Interestingly, the team found that radiologists could do better than chance in discriminating breast cancer cases from normal tissue, even when the images of abnormal breast tissue did not directly capture a cancerous lesion or when those images were taken from the contralateral breast (the breast on the other side of the body) of a woman with breast cancer.

When they compared the results to the Mouse Genomic Informatics Knockout database they found 123 genes that corresponded with functional annotation of abnormal extraembryonic tissue morphology, 121 associated with embryonic lethality, and 14 with abnormal embryo implantation.

«An appropriate pH imaging method would make it possible to visualize abnormal changes in tissue and specifically metabolic processes of tumors,» explains Franz Schilling.

Head and neck cancers are a group of diseases involved abnormal, uncontrolled cell growth in head and neck tissues.

Crigler - Najjar Syndrome is a rare genetic liver disease (incidence around 1/1 000 000 births) associated with the abnormal accumulation of bilirubin — a yellow pigment produced by the liver — in all the body's tissues, particularly the brain tissues.

In the treatment of Barrett's esophagus, physicians use pCLE to detect and remove abnormal tissue cells in a single procedure.

An abnormal mass of tissue that results when cells divide more than they should or do not die when they should.

Plasma cell neoplasms are diseases in which abnormal plasma cells or myeloma cells form tumors in the bones or soft tissues of the body.

(21) Moreover, while the link between excessive visceral adipose tissue and age - independent diabetes and metabolic syndrome widely known, recent studies suggest instead that it is the accumulation of senescent subcutaneous adipocyte progenitors — and their abnormal metabolic function — that drives similar diabetes - like phenotypes during the «normal» aging process.

This left some aspects of the abnormal «progeroid» phenotype in these organisms (the cardiovascular defects) intact, but illustrated the dysfunctional consequences of having tissues riddles with such cells.

Rather, the defective checkpoint system was left to proceed, and one of its downstream consequences, which was still under normal regulation — and one known to be directly induced by the normal degenerative aging process — was reversed at the structural level, by clearing out the p16Ink4a - positive senescent cells that had accumulated to an abnormal degree in their tissues.

In patients with antibiotic - refractory Lyme arthritis, there is mounting evidence that Lyme infection triggers an abnormal immune response, which in turn attacks the tissues of the joints, even after B. burgdorferi has been cleared by antibiotics.

Luckily, different cell types tend to have different things on their surfaces, which play particular parts in their specialized roles in the tissue, so it is a matter of identifying and targeting cell - surface markers that are specific to these abnormal cell types.

Colon and rectal cancers (CRC) occur when abnormal cells form tumors in the tissues of those body parts.