In addition, breast cancer cells respond differently to S1P in terms of the regulation
of actin cytoskeletal structures.
Not exact matches
Actin is a filamentous protein, which together with other
cytoskeletal elements forms a dynamic network
of filaments that provide both structural support, as well as critical functional capabilities, to the cell.
One such compound was docetaxel, an anticancer drug that binds tubulin, and the other jasplakinolide, which specifically binds the
cytoskeletal form
of actin.
The rapid onset
of the freezing phenotype led to the hypothesis that Mcf1 may be acting on a pre-existing eukaryotic molecular switch governing
actin cytoskeletal dynamics such as the rho GTPases.
The Wiskott - Aldrich syndrome protein regulates nuclear translocation
of NFAT2 and NF - $ ąppa $ B (RelA) independently
of its role in filamentous
actin polymerization and
actin cytoskeletal rearrangement.
Analysis
of F -
actin cytoskeletal dynamics, integrin activity, cell migration and other cell biology parameters