Orientation
of actin filaments in teleost retinal pigment epithelial cells, and the effect of the lectin, Concanavalin A, on melanosome motility.
In this way, they uncovered the mechanism which determines the functional characteristics
of actin filaments in all cells and orchestrates cellular activity.
Aside from the variation of paracrine factors between male and female cells, the team also found important differences in organization, distribution and morphology
of actin filaments in male and female hAMSCs.
Not exact matches
She wrote her dissertation on pollen sterility
in petunias, but she also studied cell structure, which led her back to animals and a postdoc at the Scripps Research Institute
in San Diego, California, where she studied a protein on the ends
of actin filaments.
When that protein is added to the receptor, the receptor gets taken out
of its nanodomain and becomes caught up
in the
actin filaments that form the cell's cytoskeleton.
The junction moves from the front to the rear
of the protozoan, probably powered by
actin and myosin protein
filaments, like those
in human muscle, constricting the protozoan and pulling the host membrane over it.
«These findings demonstrate that efficient
actin filament disassembly by GMF is essential for rapid dynamics
of cell protrusions, and that this dynamics are important for cell migration
in a three - dimensional tissue environment,» says Minna Poukkula from the research group
of professor Pekka Lappalainen.
Actin allows vital actions to be performed by assembling and disassembling itself spontaneously, continually and rapidly
in the form
of filaments that organize themselves and form networks
of parallel bundles or intertwined meshes (known as lamellar networks).
He doesn't know where he's going, but his built -
in bias to walk forward eventually gets the vesicle to its destination at the end
of the
actin filament.
A group
of plant biologists at the Institute
of Transformative Bio-Molecules (ITbM)
of Nagoya University, the University
of Tokyo, the Gregor Mendel Institute, and the University
of Kentucky, has reported
in the journal Proceedings
of the National Academy
of Sciences, on their discovery on how the plant's egg cells initially lose their skeletal pattern upon fertilization and are reorganized by two major cytoskeleton components
in the cell, microtubules (MTs) and
actin filaments (F -
actin).
Higher magnifications
of ultrathin sections shown
in C and G indicate the presence
of electron - dense DAB precipitates adjacent to F -
actin filaments.
Actin, the protein that makes up the cytoskeleton, can form long
filaments that grow
in one direction and networks
of filaments.
Providing rigidity to the cell,
actin filaments are involved
in a host
of processes including muscle contraction, cell mobility and cell division.
Beads coated with Arp2 / 3 - activating proteins can induce two distinct types
of actin organization
in cytoplasmic extracts: (1) comet tails or clouds displaying a dendritic array
of actin filaments and (2) stars with
filament bundles radiating from the bead.
Much
of this dynamic happens
in close proximity to the plasma membrane due to the fact that
actin assembly factors are membrane - bound, and thus
actin filaments are generally oriented such that their growth occurs against or near the membrane.
On the basis
of analysis
of this system, we proposed a model for filopodial formation
in which
actin filaments of a preexisting dendritic network are elongated by inhibition
of capping and subsequently cross-linked into bundles by fascin.
Fluorescence recovery after photobleaching
of GFP - tagged wild - type and S39A fascin showed that dephosphorylated fascin underwent rapid cycles
of association to and dissociation from
actin filaments in filopodia, with t (1/2) < 10 s.
Scientists are interested
in the timing
of the movement
of myosin along
actin filaments which is driven by the power stroke — a process called lever arm swing.
For the science geeks, this is an increase
in the number and size
of the
actin and myosin
filaments within a muscle.
Myofibrils, the functional units
of myocytes, composed
of actin and myosin
filaments spanning the length
of the muscle cell, do not serve as substrate for the proteasome
in their native state (45).