Reverse translation in tuberculosis: neutrophils provide clues for understanding
development of active disease Dorhoi A., Iannaccone M., Maertzdorf J., Nouailles G., Weiner J. 3rd, Kaufmann S.H.E. Frontiers in Immunol., 2014 doi: 10.3389 / fimmu.2014.00036
An effective strategy for reducing the transmission, illness and
death of active disease is the identification and treatment of LTBI to prevent progression to active disease.
Excess consumption of L - canavanine may cause abnormal blood cell counts, spleen enlargement, or the
recurrence of active disease in patients with lupus.
Although people with latent tuberculosis can not spread the disease, the ability to test for increased genetic susceptibility to
development of active disease could lead to unfair treatment of specific subpopulations that are already marginalized, and could allow familiar ethical issues surrounding the justifiability of ethnic stratification to surface [100][103].