Sentences with phrase «of active genes»

Scientists have already seen the same mark close to the start of active genes in many cells, but the team discovered that its role in egg cells is different.
The study establishes a link between TDRD3 and an enzyme that unwinds DNA at regions of active gene expression, and provides evidence that this partnership can prevent DNA breakage and chromosomal translocations - two of the hallmarks of cancer.
The 1500 transcription factors (TFs) within the human genome perform a key role in determining the set of active genes within a specific cell, as well as the magnitude of activity.
However, this study revealed that mice are more similar to humans than previously thought, with an average of around 10 % of active genes escaping X-inactivation per tissue.
Professor Siddiqui and his team identified multiple biological «micro-clusters» which means that there are different combinations of active genes in each of the reported subtypes of asthma.
Protein duo thwarts chromosomal scrambling and DNA breakage (2/11/2014) A new study by Dr. Mark Bedford establishes a link between the TDRD3 protein and an enzyme that unwinds DNA at regions of active gene expression.
He is interested in reactivating dormant genes or changing the regulation of active genes in embryos to bring back ancestral traits that have been lost in evolution.
«As a result of the previous study, we reported that SUMO is probably important for controlling expression of active genes because we found it on every gene we looked at, but only when they were turned on,» notes Rosonina.
The repertoire of active genes in their livers more closely resembled those of the northern Texas lizards, including genes involved in the functioning of the nervous and muscular systems.
These findings suggest that the acetylation reaction may not be the cause of active gene expression, or at least not sufficient to activate gene expression.
The study points to a future of active gene discovery for mental disorders» said Thomas Lehner, Ph.D., chief of the NIMH Genomics Research Branch, which funds the project.
Working copies of active genes — called messenger RNAs or mRNAs — are positioned strategically throughout living tissues, and their location often helps regulate how cells and tissues grow and develop.
What's more, 90 % of the 101 classic risk factor genes for human psychiatric diseases are also found in the cave fish genome, according to Yoshizawa's comparison of genomes and transcriptomes — surveys of active genes — in cave fish and humans.
Taking their cue from the analysis of human neocentromeres, Nagaki et al. [6] suggest that the presence of active genes indicates that rice centromere 8 is relatively «young», evolutionarily, and may have arisen from a neocentromerization event.
Unambiguous identification of exon 14 deletion in patients with suspicious Lynch syndrome reflects the main advantage of this approach, since traditional molecular methods can not distinguish the deletion of the active gene from that of the pseudogene due to frequent gene conversion between these highly homologous sequences.»
The effort yielded the first «integrative personal - omics profile,» or iPOP, documenting Snyder's unique set of active genes, metabolites, proteins and other biomolecules.
Most strikingly, muscle showed a surprisingly high rate of escapers, with over 50 % of active genes escaping X chromosome activation, a result that may be relevant to some diseases of the muscle.
The whole process is reminiscent of trial - and - error learning in which each cell explores — at its own rhythm and independently of cell division — different molecular possibilities (i.e. different genes turned on or off) before reaching a stable combination of active genes and the corresponding morphology.
The new study examined the entire set of active genes, or the transcriptome, of 24 conifers and other seed plants and three distantly related plants.
Surprisingly, she found that some of the active genes were ones that were better known for their role in the immune system, where they help fight infection.
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