Sentences with phrase «of active genes in»

Scientists have already seen the same mark close to the start of active genes in many cells, but the team discovered that its role in egg cells is different.

Professor Siddiqui and his team identified multiple biological «micro-clusters» which means that there are different combinations of active genes in each of the reported subtypes of asthma.

The repertoire of active genes in their livers more closely resembled those of the northern Texas lizards, including genes involved in the functioning of the nervous and muscular systems.

The process, reported in Human Reproduction, utilizes DNA fingerprinting (an assessment of active genes in a given cell) to boost the success rate of IVF and lower the chances of risky multiple births by identifying which of several five - day - old embryos are most likely to result in pregnancy The new method, which will replace unproved alternatives such as choosing embryos based on their shape, is likely to up the success of women becoming pregnant and lower their chances of having multiple births.

He is interested in reactivating dormant genes or changing the regulation of active genes in embryos to bring back ancestral traits that have been lost in evolution.

Not exact matches

Davies and Lineweaver suggest that genes active in embryogenesis and switched off later may be reactivated because of damage, causing the accelerated cell division of these rogue cancer cells.

To ensure the reestablishment and proliferation of this magnificent beast in today's American society, Dr. King has taken an active role in widening the bison's gene pool by selecting only gold and silver champion bison to start the herd that became Carolina Bison.

To generate a rich source of potential vaccine and drug target candidates, the team identified a set of genes that are more active in certain stages of the parasite life cycle and within the parasite's gut.

By using this tool to analyze their data the scientists were able to catalogue active alleles in a comprehensive set of mouse tissues, or the mouse «Allelome,» and gain an insight into how this differential gene activity is regulated.

McCallion's strategy to make sense of all this data looks at the active genes in cells affected by a disease, groups of genes that interact with one another, their vulnerability to mutation and information from past scientific studies to filter more than a thousand gene candidates for disease risk down to just a handful within any one implicated region.

Ueli Schibler of the University of Geneva showed in 1998 that the per genes of rat connective - tissue cells called fibroblasts are active according to a circadian cycle.

Active genes, i.e. those that produce a large amount of RNA, seem more likely to be retained than less active genes; and genes that are more active in males than in females also persist for lActive genes, i.e. those that produce a large amount of RNA, seem more likely to be retained than less active genes; and genes that are more active in males than in females also persist for lactive genes; and genes that are more active in males than in females also persist for lactive in males than in females also persist for longer.

The cap ends up close to a cluster of genes on the surrounding DNA that are involved in learning and which became more active during learning tasks.

By combining each mouse's genome, phenome, proteome and metabolome, the scientists were able to identify a particular gene, located on their chromosome 2, and whose presence plays an important role in the development of type 2 diabetes «The mice with a high - fat diet are more or less likely to develop diabetes depending on whether this gene is active or not,» said Evan Williams, LISP PhD student and the article's co-first author.

Clusters of genes that became less active were those involved in chronic inflammation, which can lead to high blood pressure and heart disease.

The lack of these genes in the neurons of active mice suggested that their brain cells did not immediately leap into an excited state in response to the stressor.

Today, a team of researchers from the University of Geneva (UNIGE), Switzerland, led by Emmanouil Dermitzakis, Louis - Jeantet Professor at the Faculty of Medicine, reveals that this is not always the case and that DNA methylation may play both a passive and active role in gene regulation.

Throughout the entire lifespan of an organism, the genetic information has to be read correctly to ensure that genes are active at the right time and in the right cells.

After having conducted a large - scale study performed on cells from the umbilical cords of 204 newborns, the researchers from UNIGE demonstrate that DNA methylation may play both a passive and active role in gene regulation.

He has been able to piggyback on previous work on the development of the chick embryo: When researchers interested in some process use a stain to show gene activity, the stain affects the whole embryo, providing clues about which genes are active in tail growth.

Those animals with more active forms of the gene had higher numbers of mu receptors in their tissues — and higher tolerances for pain.

They found that hundreds of genes active in the newborns were also active in the blastocysts from embryos that survived but not in those that failed.

If it is true that epigenetic changes to genes active in certain regions of the brain underlie our emotional and intellectual intelligence — our tendency to be calm or fearful, our ability to learn or to forget — then the question arises: Why can't we just take a drug to rinse away the unwanted methyl groups like a bar of epigenetic Irish Spring?

Together, Meaney and Szyf have gone on to publish some two - dozen papers, finding evidence along the way of epigenetic changes to many other genes active in the brain.

This gene is known to be highly active in multiple myeloma and many other cancers, raising the possibility that strategies to shut it down could be effective against a variety of tumors.

Moyer: Well one of the things we have to get rid of is gene patents and this is a kind of active issue in the courts today.

The new study «adds fuel to an active debate» about the role of accessory genes, says Alan McNally, a microbiologist at the University of Birmingham in England — whether or not the collections of genetic add - ons that bacteria maintain are shaped by natural selection, the process that fuels evolution.

Visel and his colleagues studied gene expression in a developing mouse embryo, and found 120 enhancers active in cells of the face.

The whole process is reminiscent of trial - and - error learning in which each cell explores — at its own rhythm and independently of cell division — different molecular possibilities (i.e. different genes turned on or off) before reaching a stable combination of active genes and the corresponding morphology.

In some genes, different combinations of exons can become active at different times, and each combination yields a different protein.

In Class II engagement, Sox9 binds to multiple active enhancer elements through sub-optimal, low - affinity Sox dimeric motifs (DNA sequences), resulting in a high level of transcription of cartilage - related geneIn Class II engagement, Sox9 binds to multiple active enhancer elements through sub-optimal, low - affinity Sox dimeric motifs (DNA sequences), resulting in a high level of transcription of cartilage - related genein a high level of transcription of cartilage - related genes.

«One of the ways SUMO does this is by promoting the binding of Tup1 to active genes, which then acts to reduce their expression to appropriate levels,» explains Rosonina, in the Faculty of Science at York U.

Initial tests on mice showed the hybrid virus was very efficient: the gene it carried was active in 24 per cent of airway cells after two months, a far better proportion than achieved by other delivery methods (New Scientist, 10 March 2001, p 19).

After two months the gene was active in 21 per cent of cells, Kobinger told New Scientist.

The two closely related regulatory genes are active in the normal development of mammals and govern how RNAs produced from the genes are joined to make final versions of the encoded protein, a process called alternative splicing.

By taking a sort of molecular snapshot of an astrocyte's ribosomes, it's possible to see all the mRNA copies in progress and thus know which genes are active.

Fully a third of our genes, he suspects, will turn out to be active only in the brain; he's found 3,000 of them already.

In this study, the team was able to piece together the biological process that leads to the production of new bone by studying the offspring of mice lacking the Gastric Intrinsic Factor gene, which is active in the stomach and allows the gut to absorb vitamin B1In this study, the team was able to piece together the biological process that leads to the production of new bone by studying the offspring of mice lacking the Gastric Intrinsic Factor gene, which is active in the stomach and allows the gut to absorb vitamin B1in the stomach and allows the gut to absorb vitamin B12.

They found that the more efficient a mutant was at turning on genes, the more time it spent flipped into the active shape, they report in the 23 March issue of Science.

Labs have started tackling the problem with a tool called single - cell transcriptome analysis, which gives readouts of all the genes that are active in individual cells.

Researchers at UC Davis have found that a gene, which is not active in some mothers, produces a breast milk sugar that influences the development of the community of gut bacteria in her infant.

To their surprise, a gene called 3beta - HSD, which plays a role in synthesis of steroid hormones, was less active in the experimental cells.

Shaw reverses the process in a new paper, taking what he finds in humans back to the flies and gaining new insight into humans as a result: identification of a human gene that is more active after sleep deprivation.

The study found that, on average, Bifidobacterium were established earlier and more frequently in infants fed by women with an active copy of the gene, the secretors, than without one, the non-secretors.

An active international research has been carried out for several years in order to identify candidate genes which explain the origin and development of the disease.

They found a distinctive subset of genes was active in the nonresponsive bees.

The gene isn't active on the other side of the wing, they found, because Engrailed - 1, another gene first found in flies, suppresses it.

So researchers began testing genes that were only active in embryonic stem cells to try to pin down those capable of triggering the change.

They have discovered that a single amino acid difference in the structure of histone H3.3 enables it to serve as a kind of memory device for the cell, marking genes that need to remain active.

In separate studies reported in today's issue of Nature, a team led by geneticist Juan Carlos Ispisúa Belmonte at the Salk Institute in La Jolla, California, and another led by geneticist Cliff Tabin at Harvard Medical School found a very similar gene in chicks, named Radical fringe (R - fng), that is active on one side of a budding chick winIn separate studies reported in today's issue of Nature, a team led by geneticist Juan Carlos Ispisúa Belmonte at the Salk Institute in La Jolla, California, and another led by geneticist Cliff Tabin at Harvard Medical School found a very similar gene in chicks, named Radical fringe (R - fng), that is active on one side of a budding chick winin today's issue of Nature, a team led by geneticist Juan Carlos Ispisúa Belmonte at the Salk Institute in La Jolla, California, and another led by geneticist Cliff Tabin at Harvard Medical School found a very similar gene in chicks, named Radical fringe (R - fng), that is active on one side of a budding chick winin La Jolla, California, and another led by geneticist Cliff Tabin at Harvard Medical School found a very similar gene in chicks, named Radical fringe (R - fng), that is active on one side of a budding chick winin chicks, named Radical fringe (R - fng), that is active on one side of a budding chick wing.