We also investigate the biological role
of adenosine deaminases of tRNAs (ADATs).
The assay mixtures were prepared in 25 mM potassium phosphate buffer pH 7.5, 1 mM EDTA, 2 mM MgCl2, 0.01 % Triton X-100 with 5 µM SAHH, 0.3 U / ml
of adenosine deaminase from Sigma, 25 µM SAM, and 15 µM Thioglo - 1.
Not exact matches
In another landmark success, scientists in Italy and the United States cured «bubble» babies who have a malfunctioning gene for the enzyme
adenosine deaminase, which causes a buildup
of toxic products that destroy immune cells.
C. elegans is a microscopic worm that like humans highly expresses a family
of proteins in the nervous system called ADARs —
adenosine deaminases that act on RNA — a family that includes ADR - 1.
There are many causes
of this disorder; in Katlyn's case it was lack
of the enzyme
adenosine deaminase, or ADA, which rids the body
of a natural toxin called deoxyadenosine.
«
Adenosine deaminase may help the immune system fight HIV on its own:
Adenosine deaminase enhances anti-HIV-1 specific immune responses by reducing the action
of cells that impede HIV - specific defenses.»
One type
of immune deficiency in humans is caused by deficiency
of an enzyme called
adenosine deaminase, or ADA.
This is in addition to the licensing
of products such as GlaxoSmithKline's Strimvelis ex-vivo stem - cell therapy for treatment
of severe combined immunodeficiency caused by
adenosine deaminase deficiency (ADA - SCID) in 2016 (1)-- has led to an increase in demand for therapeutic vector manufacturing capabilities.
She characterized a family
of enzymes called ADAR (
adenosine deaminase acting on RNA) that are responsible for RNA editing.