Sentences with phrase «of adipocyte size»

Prolonged decrease of adipocyte size after rosiglitazone treatment in high - and low - fat - fed rats.

The close relationship between adipocyte size and the abundance of macrophages in adipose tissue suggests that the influence of adipocyte size on adipocyte function may be conveyed through a paracrine pathway involving adipose tissue macrophages.

Not exact matches

This phenomenon is more frequent in obese patients, in whom the size and number of PPAT adipocyte cells are higher.

The accumulation of adipose tissue macrophages in direct proportion to adipocyte size and body mass may explain the coordinated increase in expression of genes encoding macrophage markers observed in our microarray expression data.

Our data in humans and mice show that adipocyte size is a strong predictor of the percentage of macrophages in adipose tissue (Figure 3e).

These data demonstrate that variations in continuous quantitative traits such as body mass, adipocyte size, and BMI are correlated with quantitative variations in the expression of genes.

In subcutaneous and parametrial adipose tissue, the mean adipocyte size of the FVB / NJ Csf1op / op mice (311 ± 71 μm2) was smaller though not significantly different from that of control FVB / NJ Csf1 + / + mice (476 ± 326 μm2)(P = 0.37).

In mice, both body mass and adipocyte size were strong predictors of the percentage of F4 / 80 + macrophages in the perigonadal, perirenal, mesenteric, and subcutaneous adipose tissue depots.

Immunohistochemical analysis of perigonadal, perirenal, mesenteric, and subcutaneous adipose tissue revealed that the percentage of cells expressing the macrophage marker F4 / 80 (F4 / 80 +) was significantly and positively correlated with both adipocyte size and body mass.

Immunohistochemical analysis of human subcutaneous adipose tissue showed that both BMI and adipocyte size were strong predictors of the percentage of CD68 - expressing macrophages.

The researchers selectively ablated Lsd1 and inactivated its catalytic activity in brown adipocytes, which triggered a profound whitening of brown adipose tissue: The colour of the brown fat cells became paler, their size increased and they started to store energy instead of expending it.

Overgrown tissue was composed of normal - sized, UCP1 - negative unilocular adipocytes, with mitochondrial network fragmentation, disorganised cristae, and increased autophagosomes.

«Effects of Modified Alternate - Day Fasting Regimens on Adipocyte Size, Triglyceride Metabolism, and Plasma Adiponectin Levels in Mice,» Journal of Lipid Research, 48 (10), 2212 - 2219.

When you gain body fat, it's a combination of growth in fat cell size and the formation of new adipocytes (aka fat cells) through a process called adipogenesis, or adipocyte differentiation [13].