Inflammatory breast cancer is the most aggressive
type of advanced breast cancer and is characterized by rapid development, resistance to chemotherapy, early metastases and a poor prognosis.
«However, when we investigated the effect of extending the screening program in The Netherlands from age 69 to 75, we found that it had not led to a decrease in the
rate of advanced breast cancers detected, while the numbers of early stage tumors strongly increased.
Female breast cancer: There has been a progression towards early diagnosis of breast cancer statewide, especially in San Francisco Bay Area, Sacramento, San Diego and the High Sierra regions, but pockets of late - stage diagnoses persist in Del Norte - Humboldt and in San Bernardino, Kern, Merced and Kings counties, which had the highest
proportion of advanced breast cancers diagnoses in the state.
«Metastatic brain tumors — often from lung, breast or skin cancers — are the most commonly observed tumors within the brain and account for about 30
percent of advanced breast cancer metastases,» says Khalid Shah, MS, PhD, director of the Molecular Neurotherapy and Imaging Laboratory in the MGH Departments of Radiology and Neurology, who led the study.
My honours project was centred upon exploring mechanisms that allow for the progression of Inflammatory Breast Cancer, a highly rare and aggressive
form of advanced breast cancer, and whether we could target these previously unknown mechanisms with novel therapeutics.
Bone metastases occur in up to 70 %
of advanced breast cancer.