Sentences with phrase «of adverse effects for»

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

As for the ecosystem, the FDA concluded that the chance of any adverse effects «is largely negligible.»

Utilized in Chinese and South American medicine for centuries, adaptogens have been gaining popularity in the U.S. for their ability to counteract the adverse effects of stress by adapting to an individual's physical needs and normalizing imbalances.

«These adverse effects would weaken the credit quality of bank's loan portfolios and could lead to tighter lending conditions for households and businesses.

These risks and uncertainties include competition and other economic conditions including fragmentation of the media landscape and competition from other media alternatives; changes in advertising demand, circulation levels and audience shares; the Company's ability to develop and grow its online businesses; the Company's reliance on revenue from printing and distributing third - party publications; changes in newsprint prices; macroeconomic trends and conditions; the Company's ability to adapt to technological changes; the Company's ability to realize benefits or synergies from acquisitions or divestitures or to operate its businesses effectively following acquisitions or divestitures; the Company's success in implementing expense mitigation efforts; the Company's reliance on third - party vendors for various services; adverse results from litigation, governmental investigations or tax - related proceedings or audits; the Company's ability to attract and retain employees; the Company's ability to satisfy pension and other postretirement employee benefit obligations; changes in accounting standards; the effect of labor strikes, lockouts and labor negotiations; regulatory and judicial rulings; the Company's indebtedness and ability to comply with debt covenants applicable to its debt facilities; the Company's ability to satisfy future capital and liquidity requirements; the Company's ability to access the credit and capital markets at the times and in the amounts needed and on acceptable terms; and other events beyond the Company's control that may result in unexpected adverse operating results.

In developing the National OCS Program, which has also been known as a Five Year Program, the Secretary is required to achieve an appropriate balance among the potential for environmental impacts, for discovery of oil and gas, and for adverse effects on the coastal zone.

For example, the expected timing and likelihood of completion of the proposed merger, including the timing, receipt and terms and conditions of any required governmental and regulatory approvals of the proposed merger that could reduce anticipated benefits or cause the parties to abandon the transaction, the ability to successfully integrate the businesses, the occurrence of any event, change or other circumstances that could give rise to the termination of the merger agreement, the possibility that Kraft shareholders may not approve the merger agreement, the risk that the parties may not be able to satisfy the conditions to the proposed transaction in a timely manner or at all, risks related to disruption of management time from ongoing business operations due to the proposed transaction, the risk that any announcements relating to the proposed transaction could have adverse effects on the market price of Kraft's common stock, and the risk that the proposed transaction and its announcement could have an adverse effect on the ability of Kraft and Heinz to retain customers and retain and hire key personnel and maintain relationships with their suppliers and customers and on their operating results and businesses generally, problems may arise in successfully integrating the businesses of the companies, which may result in the combined company not operating as effectively and efficiently as expected, the combined company may be unable to achieve cost - cutting synergies or it may take longer than expected to achieve those synergies, and other factors.

Based on the results of this assessment, Tesla does not believe that its compensation policies and practices for all employees, including non-executive officers, create risks that are reasonably likely to have a material adverse effect on Tesla.

For example, the loss of existing firms and the low creation rate of new firms during and after the Great Recession have not only directly reduced investment but also impaired the dynamism of the private sector, causing persistent, adverse effects on productivity growth.12

In addition, there are proposals for tax legislation that have been introduced or that are being considered that could have a significant adverse effect on our tax rate, the carrying value of deferred tax assets, or our deferred tax liabilities.

On a blended same - restaurant sales basis, results for Olive Garden, Red Lobster and LongHorn Steakhouse were down 1.9 % in the fourth quarter, which includes the adverse effect of an earlier Lenten season and Easter that impacted blended same - restaurant sales by 40 basis points.

HAZELTON — A federal environmental assessment report that concluded the proposed New Prosperity open - pit mine would have significant adverse effects for the Tsilhqot» in is a condemnation of the B.C. Liberals approach to Aboriginal rights and title, says Stikine MLA Doug...

For example, they staged a walk - out at COP19 at Warsaw when their proposal for a loss and damage mechanism, which would contribute to addressing damages occurring from adverse effects of climate change, did not receive enough tractiFor example, they staged a walk - out at COP19 at Warsaw when their proposal for a loss and damage mechanism, which would contribute to addressing damages occurring from adverse effects of climate change, did not receive enough tractifor a loss and damage mechanism, which would contribute to addressing damages occurring from adverse effects of climate change, did not receive enough traction.

However, reduced purchasing - power for money is not the most important adverse effect of monetary inflation.

Besides, to make the platform more personalised for users, the latest strategy of Mark Zuckerberg — Less is More — will have a more adverse effect on brands and marketers.

IF THE COMPANY BELIEVES, IN ITS SOLE DISCRETION, THAT ANY INDIVIDUALS OR ENTITIES OWNING CTK CREATES MATERIAL REGULATORY OR OTHER LEGAL RISKS OR ADVERSE EFFECTS FOR THE COMPANY AND / OR CTK, THE COMPANY RESERVES THE RIGHT TO: (A) BUY ALL CTK FROM SUCH CTK OWNERS AT THE THEN - EXISTING MARKET PRICE AND / OR (B) SELL ALL CRYPTOCURRENCY ASSETS OF THE COMPANY.

but fortunately there are psychologists, mental health practitioners and others who do and I have benefitted greatly from their work, personal testimonies and the various articles / publications which they have produced --(for example, The Journal of Transpersonal Psychology; The Religious & Spiritual Problems category in the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM - IV) published by the American Psychiatric Association; The US National Library of Medicine National Institutes of Health PubMed.gov database of healthcare and scientific literature)-- about the adverse psychological effects which can arise when persons engage in intense / deep spiritual practices such as intense / deep prayer, fasting and meditation which alter their state of consciousness.

Based on your comments above regarding the Buddhists monks, it is clear / obvious that if I didn't experience adverse effects when engaging in intense / deep prayer and meditation but instead experienced oneness and tranquility just like the Buddhist monks then for sure, you wouldn't accuse me of being an unorthodox enthusiast engaging in self - manufactured religion.

Finally, observe the two remarkable passages, 9:2 - 7 and 11:1 - 9 (which very well may be Isaianic, despite considerable adverse critical judgment), looking forward to the ultimate fulfillment of the David - Zion covenant (for Isaiah, the covenant) in a Messiah, an «anointed one,» in and through whose rule «the zeal of Yahweh of hosts» (9:7) will effect justice and righteousness (in the theologically dependent sense) not only in Israel but in all the earth (11:4 - 9).

I thank Michael Knower for his insightful «on - the - ground» report as a palliative care physician in Oregon, which affords him firsthand experience with the adverse effects of the law permitting assisted suicide.

Burial ground being the ocean was a wise choice made although might have adverse effects since when there is no body then there is no death or crime... so might just become a «Living Legend»... It is hard for me to believe that any land grave would have made people treat as holy man grave that might followers visit as visiting the grave of the prophet or other holy men or of the prophets house family..??

When Justice Kennedy asserts that there is no rational basis for the amendment, and that the «inevitable inference» is that the action is «born of animosity toward the class of persons affected,» he is saying, in judicial terms of art, that the amendment was adopted «because of» and not merely «in spite of» its adverse effects upon an identifiable group.

As for mood and concentration, research was able to show that two days of calorie deprivation did not cause any adverse effects on concentration, activity, sleep nor mood when the subjects were unaware of how many calories they were consuming!

You need to rinse your body very thoroughly though, since the ground coffee will stick to your body like the devil, but since the coffee will be flushed out of the tub / shower with PLENTY of water (for above mentioned reason), I haven't been able to see any adverse effects on the plumbing yet.

When inflammation strikes, we are conditioned into reaching for a quick fix in the way of pharmaceutical or prescribed drugs such as aspirin and ibuprofen, temporary panacea's that come with their own adverse side effects and with long term use have the potential to create a host of health problems independently.

Too much omega 6 in ones diet WITHOUT the balance of omega 3's (and omega 9's) can cause adverse effects for many people.

Based on this review, they concluded that the general population of healthy adults is not at risk for potential adverse effects from caffeine if they limit their consumption to 400 mg per day.

The publisher and authors are not responsible for any adverse effects or consequences resulting from the use of the suggestions, products or procedures that appear in this magazine.

Rod Sims gave two reasons for the appeal: «First, because of the adverse effect of the proposed acquisition on independent supermarket retailers, consumers and competition in the NSW and ACT grocery sector.

NSF International is a global independent organization that writes standards and tests and certifies products for the water, food, health sciences and consumer goods industries to minimize adverse health effects and protect the environment as well as offering a range of standardized and proprietary methods of measuring sustainability for organizations, products, processes, supply chains and services.

It should be noted that we closely monitored our subjects for any possible adverse effects after the consumption of Golden Rice and found no evidence of any problems, including allergic reactions or gastrointestinal disturbance.

It has to persist for generations of relationships between very close relatives before having any adverse effects.

With Inter continuing to battle for a Champions League spot this season, it remains to be seen if failure to book a place at Europe's top table has an adverse effect on their ability to keep him at the San Siro, but according to Calciomercato the fear of losing him is growing.

Gary Monk deserves plenty of plaudits for the job he's done at Swansea, but the departure of Wilfried Bony has clearly had an adverse effect.

So, whereas I was of the opinion that heading into Monday's encounter no longer top of the league would have a negative effect on the team, it will instead empower them with so much reassurance and positivity that any sort of result would be enough to keep them on course for the title, but it does also mean they're there to be shot at so don't be at all surprised if United come sprinting out of the blocks this evening and put the Gunners to the sword very early on as don't forget, United had top - spot stolen away from them because of the recent bout of adverse weather.

One of the most important and influential studies of the long - term effects of childhood stress and trauma is the Adverse Childhood Experiences study, which was conducted in the 1990s by Robert Anda, a physician at the Centers for Disease Control and Prevention, and Vincent Felitti, the founder of the department of preventive medicine at Kaiser Permanente, the giant health - maintenance organization based in California.

Since social media has become an integral part of everyday life for many young adults, it is important to address its adverse effects on stress levels and well - being.

I believe it is worth giving a try, seeing as it has so few potential adverse side effects compared to its over-the-counter competition and has been trusted around the world for centuries as the «go - to» medicinal herb for quite the wide variety of ailments.

If a mother is not breastfeeding, she is able to take these effects of the medicines but for a baby, the results could be adverse to take.

«I think parents who feed their children formulas, whether soy or milk, should not worry about any adverse effects,» senior researcher Thomas M. Badger, a professor at the University of Arkansas for Medical Sciences in Little Rock, said in an email.

On the one hand, there appears to be a growing body of research suggesting that playing contact or collision sports for a long period of time likely has, at least for some unknown percentage of athletes, serious adverse health consequences, not just from concussions but from the cumulative effect of sub-concussive blows to the head, blows which athletes in youth football, lacrosse, and, until recently, hockey, suffer on an almost constant basis in both games and practices.

«A growing body of research points to the potential for arsenic to cause adverse health effects at low levels.

The American FDA has already issued a warning about the adverse effects of numbing medications for teething pain.

about the adverse effects of numbing medications for teething pain.

Divorce Lingers On: Adverse Effects On Kids Often Delayed Until Adulthood by Michelle Quinn, San Jose Mercury News For Beth Wolff, the effects of her parents» divorce almost 30 years ago...

One must also account for the «invisible thorn,» which is wheat lectin — known more technically as Wheat Germ Agglutinin (WGA)-- and which can cause a broad range of adverse health effects, even while being undetected through conventional screenings.

In consideration of potential adverse effects, we recommend pacifier use for infants up to 1 year of age, which includes the peak ages for SIDS risk and the period in which the infant's need for sucking is highest.

But for parents who are concerned about the possible adverse effects of solitary sleep training — or who just prefer to soothe their babies because it feels intuitively right — the promise of fewer night wakings is not enough to change their minds.

Dr. Sachs: Caution is advised for nursing women using narcotic pain relievers because of the potential for adverse effects in nursing infants, and some are not recommended at all for use in nursing women because they are concentrated in breast milk.