Similarly nonclinical studies show no evidence
of adverse effects in animals (see section 5.3).
This report also mentions that the EPA has received reports
of adverse effects in pets and promises further evaluation.
I know
some of the adverse effects in men, I ended up with micropenis and ED but I am trying to understand the adverse effects on women.
Manufacturers began to substitute this compound for a chemical cousin — bisphenol A, or BPA — when research showed BPA mimicked the hormone estrogen and could provoke a number
of adverse effects in laboratory animals.
Not exact matches
Important factors that could cause actual results to differ materially from those reflected
in such forward - looking statements and that should be considered
in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability
of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost
of accommodating, announced increases
in the build rates
of certain aircraft; 6) the
effect on aircraft demand and build rates
of changing customer preferences for business aircraft, including the
effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest
in the Middle East or Asia; 7) customer cancellations or deferrals as a result
of global economic uncertainty or otherwise; 8) the
effect of economic conditions
in the industries and markets
in which we operate
in the U.S. and globally and any changes therein, including fluctuations
in foreign currency exchange rates; 9) the success and timely execution
of key milestones such as the receipt
of necessary regulatory approvals, including our ability to obtain
in a timely fashion any required regulatory or other third party approvals for the consummation
of our announced acquisition
of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability
of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk
of nonpayment by such customers; 13) any
adverse impact on Boeing's and Airbus» production
of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts
of terrorism; 14) any
adverse impact on the demand for air travel or our operations from the outbreak
of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact
of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition
of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the
effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both
in the U.S. and abroad; 20) the
effect of changes
in tax law, such as the
effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations
of or guidance related thereto, and the Company's ability to accurately calculate and estimate the
effect of such changes; 21) any reduction
in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability
of raw materials and purchased components; 23) our ability to recruit and retain a critical mass
of highly - skilled employees and our relationships with the unions representing many
of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment
of interest on, and principal
of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness
of any interest rate hedging programs; 28) the effectiveness
of our internal control over financial reporting; 29) the outcome or impact
of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition
of Asco
in a timely matter while avoiding any unexpected costs, charges, expenses,
adverse changes to business relationships and other business disruptions for ourselves and Asco as a result
of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks
of doing business internationally, including fluctuations
in foreign current exchange rates, impositions
of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
In fact, banning abortion may actually have an
adverse effect on reducing the number
of women seeking abortions.
These risks and uncertainties include, among others: the unfavorable outcome
of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any
of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA
in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components
of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence
of efficacy and adequacy
of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results
of our clinical development activities may not be positive, or predictive
of real - world results or
of results
in subsequent clinical trials; regulatory submissions may not occur or be submitted
in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction
in payment rate or reimbursement for the company's products or an increase
in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make
adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights
of third parties, or have unintended side
effects,
adverse reactions or incidents
of misuse; and those risks and uncertainties described under the heading «Risk Factors»
in the company's most recent Annual Report on Form 10 - K and
in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.
«There is conclusive evidence that intentional or accidental exposure to e-liquids» — the chemicals
in the vaping cartridge that, when heated, release the aerosolized inhalant
of nicotine and perhaps one
of 7,700 flavors — «can result
in adverse health
effects such as seizures, anoxic brain injury, vomiting, and lactic acidosis.»
Alcoa had voluntarily shut - off the plant's burner
in 2002 after a number
of multi-million dollar compensation claims were made against the company by workers relating to
adverse health
effects.
One
of the
adverse side
effects of goals is that they can result
in a bit
of tunnel vision.
The Healthcare Reform Law, including The Patient Protection and Affordable Care Act and The Healthcare and Education Reconciliation Act
of 2010, could have a material
adverse effect on Humana's results
of operations, including restricting revenue, enrollment and premium growth
in certain products and market segments, restricting the company's ability to expand into new markets, increasing the company's medical and operating costs by, among other things, requiring a minimum benefit ratio on insured products, lowering the company's Medicare payment rates and increasing the company's expenses associated with a non-deductible health insurance industry fee and other assessments; the company's financial position, including the company's ability to maintain the value
of its goodwill; and the company's cash flows.
In its latest Winter Business Outlook Survey conducted by the Bank
of Canada, the
adverse effects of the oil crash continue to spread beyond the resource sector to other regions and industries.
Utilized
in Chinese and South American medicine for centuries, adaptogens have been gaining popularity
in the U.S. for their ability to counteract the
adverse effects of stress by adapting to an individual's physical needs and normalizing imbalances.
«Those costs may have a material
adverse effect on The Home Depot's financial results
in the fourth quarter
of fiscal 2014 and / or future periods,» the company said.
These risks and uncertainties include competition and other economic conditions including fragmentation
of the media landscape and competition from other media alternatives; changes
in advertising demand, circulation levels and audience shares; the Company's ability to develop and grow its online businesses; the Company's reliance on revenue from printing and distributing third - party publications; changes
in newsprint prices; macroeconomic trends and conditions; the Company's ability to adapt to technological changes; the Company's ability to realize benefits or synergies from acquisitions or divestitures or to operate its businesses effectively following acquisitions or divestitures; the Company's success
in implementing expense mitigation efforts; the Company's reliance on third - party vendors for various services;
adverse results from litigation, governmental investigations or tax - related proceedings or audits; the Company's ability to attract and retain employees; the Company's ability to satisfy pension and other postretirement employee benefit obligations; changes
in accounting standards; the
effect of labor strikes, lockouts and labor negotiations; regulatory and judicial rulings; the Company's indebtedness and ability to comply with debt covenants applicable to its debt facilities; the Company's ability to satisfy future capital and liquidity requirements; the Company's ability to access the credit and capital markets at the times and
in the amounts needed and on acceptable terms; and other events beyond the Company's control that may result
in unexpected
adverse operating results.
In developing the National OCS Program, which has also been known as a Five Year Program, the Secretary is required to achieve an appropriate balance among the potential for environmental impacts, for discovery
of oil and gas, and for
adverse effects on the coastal zone.
For example, the expected timing and likelihood
of completion
of the proposed merger, including the timing, receipt and terms and conditions
of any required governmental and regulatory approvals
of the proposed merger that could reduce anticipated benefits or cause the parties to abandon the transaction, the ability to successfully integrate the businesses, the occurrence
of any event, change or other circumstances that could give rise to the termination
of the merger agreement, the possibility that Kraft shareholders may not approve the merger agreement, the risk that the parties may not be able to satisfy the conditions to the proposed transaction
in a timely manner or at all, risks related to disruption
of management time from ongoing business operations due to the proposed transaction, the risk that any announcements relating to the proposed transaction could have
adverse effects on the market price
of Kraft's common stock, and the risk that the proposed transaction and its announcement could have an
adverse effect on the ability
of Kraft and Heinz to retain customers and retain and hire key personnel and maintain relationships with their suppliers and customers and on their operating results and businesses generally, problems may arise
in successfully integrating the businesses
of the companies, which may result
in the combined company not operating as effectively and efficiently as expected, the combined company may be unable to achieve cost - cutting synergies or it may take longer than expected to achieve those synergies, and other factors.
As a result, political instability, labor strikes, natural disasters or other events resulting
in the disruption
of trade or transportation from other countries or the imposition
of additional regulations relating to duties upon imports could cause significant delays or interruptions
in the supply
of our merchandise or increase our costs, either
of which could have an
adverse effect on our business.
«Negative publicity or public opinion resulting from these matters may increase the risk
of reputational harm to our business, which can impact our ability to keep and attract customers, our ability to attract and retain qualified team members, result
in the loss
of revenue, or have other material
adverse effects on our results
of operations and financial condition.»
There are other aspects
of the NGP Report that merit further discussion, including its approach to adaptive management (we now have three different JRP reports
in as many years that take different views on the extent to which AM can be relied upon
in making a determination as to the likelihood
of significant
adverse environmental
effects under CEAA), the precautionary principle, species at risk and Aboriginal consultation.
The Governor
in Council accepted the panel's recommendations that the pipeline will have significant
adverse environmental
effects to populations
of woodland caribou and grizzly bears, but that these
effects are justified
in the circumstances.
These developments, or the perception that any
of them could occur, have had and may continue to have a significant
adverse effect on global economic conditions and the stability
of global financial markets, and could significantly reduce global market liquidity and restrict the ability
of key market participants to operate
in certain financial markets.
Any consequences resulting from inaccuracies or delays
in our reported financial statements could have an
adverse effect on the trading price
of our common stock as well as an
adverse effect on our business, operating results and financial condition.
In addition, there are proposals for tax legislation that have been introduced or that are being considered that could have a significant
adverse effect on our tax rate, the carrying value
of deferred tax assets, or our deferred tax liabilities.
On a blended same - restaurant sales basis, results for Olive Garden, Red Lobster and LongHorn Steakhouse were down 1.9 %
in the fourth quarter, which includes the
adverse effect of an earlier Lenten season and Easter that impacted blended same - restaurant sales by 40 basis points.
In credit - fueled economies, the absence
of cheap credit could have
adverse effects.
HAZELTON — A federal environmental assessment report that concluded the proposed New Prosperity open - pit mine would have significant
adverse effects for the Tsilhqot»
in is a condemnation
of the B.C. Liberals approach to Aboriginal rights and title, says Stikine MLA Doug...
Yet each time the requisite agreement has been impeded by various parties expressing concerns over the potential
adverse effects of companion hikes
in CPP premiums.
It is possible that, given the publicity surrounding developments
in Asia and their
adverse effect on confidence, businesses may be somewhat more cautious
in their hiring plans than would normally be expected following a strong period
of economic growth.
IF THE COMPANY BELIEVES,
IN ITS SOLE DISCRETION, THAT ANY INDIVIDUALS OR ENTITIES OWNING CTK CREATES MATERIAL REGULATORY OR OTHER LEGAL RISKS OR
ADVERSE EFFECTS FOR THE COMPANY AND / OR CTK, THE COMPANY RESERVES THE RIGHT TO: (A) BUY ALL CTK FROM SUCH CTK OWNERS AT THE THEN - EXISTING MARKET PRICE AND / OR (B) SELL ALL CRYPTOCURRENCY ASSETS
OF THE COMPANY.
Foreign investments can be riskier and more volatile than U.S. investments due to the
adverse effects of currency exchange rates, differences
in market structure and liquidity, as well as political and economic developments
in foreign countries and regions (e.g., «Brexit»).
To answer your question some
of the
adverse effects include: 1) Sendinga clear message that the following government proceedings are
in some way bound by the beliefs
of Christianity.
In these cases, the ethics
of justice make two demands: that the negative impact on the environment and on certain people will be offset by a clear benefit to the larger society, and that individuals and communities suffering
adverse effects are offered a means
of redress and are duly compensated.
but fortunately there are psychologists, mental health practitioners and others who do and I have benefitted greatly from their work, personal testimonies and the various articles / publications which they have produced --(for example, The Journal
of Transpersonal Psychology; The Religious & Spiritual Problems category
in the Diagnostic and Statistical Manual
of Mental Disorders, 4th Edition (DSM - IV) published by the American Psychiatric Association; The US National Library
of Medicine National Institutes
of Health PubMed.gov database
of healthcare and scientific literature)-- about the
adverse psychological
effects which can arise when persons engage
in intense / deep spiritual practices such as intense / deep prayer, fasting and meditation which alter their state
of consciousness.
Based on your comments above regarding the Buddhists monks, it is clear / obvious that if I didn't experience
adverse effects when engaging
in intense / deep prayer and meditation but instead experienced oneness and tranquility just like the Buddhist monks then for sure, you wouldn't accuse me
of being an unorthodox enthusiast engaging
in self - manufactured religion.
We believe that imposing this burden on our men and women
in uniform would undermine recruiting and retention, impact leadership at all levels, have
adverse effects on the willingness
of parents who lend their sons and daughters to military service, and eventually break the All - Volunteer Force.
Finally, observe the two remarkable passages, 9:2 - 7 and 11:1 - 9 (which very well may be Isaianic, despite considerable
adverse critical judgment), looking forward to the ultimate fulfillment
of the David - Zion covenant (for Isaiah, the covenant)
in a Messiah, an «anointed one,»
in and through whose rule «the zeal
of Yahweh
of hosts» (9:7) will
effect justice and righteousness (
in the theologically dependent sense) not only
in Israel but
in all the earth (11:4 - 9).
I thank Michael Knower for his insightful «on - the - ground» report as a palliative care physician
in Oregon, which affords him firsthand experience with the
adverse effects of the law permitting assisted suicide.
Discriminatory purpose, as defined
in Bray, implies that the agent selects or reaffirms a particular course
of action
in part «because
of» and not merely «
in spite
of» its
adverse effects upon an identifiable group.
When Justice Kennedy asserts that there is no rational basis for the amendment, and that the «inevitable inference» is that the action is «born
of animosity toward the class
of persons affected,» he is saying,
in judicial terms
of art, that the amendment was adopted «because
of» and not merely «
in spite
of» its
adverse effects upon an identifiable group.
In the vaguest terms, it covers such things as «harboring» anyone who has ever aided acts
of terrorism that might have had «
adverse effects» on the U.S. economy or foreign policy.
When inflammation strikes, we are conditioned into reaching for a quick fix
in the way
of pharmaceutical or prescribed drugs such as aspirin and ibuprofen, temporary panacea's that come with their own
adverse side
effects and with long term use have the potential to create a host
of health problems independently.
In other parts
of the world, he explains, farms use a lot
of mechanization and industrialization to produce large quantities
of abalone, but this has an
adverse effect on their flavor.
In California avocado groves, cool temperatures before and during the main period
of bloom can have an
adverse effect on avocado production.
In its report, WHO notes that it does not include the sugars in fresh fruits and vegetables, or sugars naturally present in milk, because «there is no reported evidence of adverse effects of consuming these sugars.&raqu
In its report, WHO notes that it does not include the sugars
in fresh fruits and vegetables, or sugars naturally present in milk, because «there is no reported evidence of adverse effects of consuming these sugars.&raqu
in fresh fruits and vegetables, or sugars naturally present
in milk, because «there is no reported evidence of adverse effects of consuming these sugars.&raqu
in milk, because «there is no reported evidence
of adverse effects of consuming these sugars.»
Too much omega 6
in ones diet WITHOUT the balance
of omega 3's (and omega 9's) can cause
adverse effects for many people.
Growth was more muted
in Europe, which saw EBITs up 0.6 % to AUS$ 48 million, largely as a result
of the exchange rate driven by the devaluation
of Sterling (excluding this
adverse effect saw EBIT increase 46 % across the region).
In view
of this it should avoid the use
of fertilizers, pesticides, animal drugs and food additives that may have
adverse health
effects.
The publisher and authors are not responsible for any
adverse effects or consequences resulting from the use
of the suggestions, products or procedures that appear
in this magazine.
Rod Sims gave two reasons for the appeal: «First, because
of the
adverse effect of the proposed acquisition on independent supermarket retailers, consumers and competition
in the NSW and ACT grocery sector.