Sentences with phrase «of adverse events from»

After the Environmental Protection Agency's extensive review of adverse events from spot - on flea and tick products for pets, the agency has given manufacturers six months to change their labels to help prevent even more problems than the 44,000 illnesses and 600 deaths reported in 2008.

This means that puppies that receive needless vaccines not only suffer the risk of adverse events from the vaccine, but they are more at risk of picking up any other virus or bacterium that crosses their path because their immune system has been overloaded by the vaccine itself.

Just how big a problem was unclear, however, because FDA hears about only a tiny fraction of adverse events from the companies, they noted.

Not exact matches

When interests between management and shareholders become adverse, even through the regular course of events, it's important for boards to have their own set of lawyers who are independent from management and seen as objective and willing to act in the interest of directors, not management, and ultimately shareholders.

The Finnish drug maker on Sunday presented results from phase I trial of a prostate cancer treatment, saying according the data it «has been well tolerated, with no significant treatment - related adverse events.»

These risks and uncertainties include competition and other economic conditions including fragmentation of the media landscape and competition from other media alternatives; changes in advertising demand, circulation levels and audience shares; the Company's ability to develop and grow its online businesses; the Company's reliance on revenue from printing and distributing third - party publications; changes in newsprint prices; macroeconomic trends and conditions; the Company's ability to adapt to technological changes; the Company's ability to realize benefits or synergies from acquisitions or divestitures or to operate its businesses effectively following acquisitions or divestitures; the Company's success in implementing expense mitigation efforts; the Company's reliance on third - party vendors for various services; adverse results from litigation, governmental investigations or tax - related proceedings or audits; the Company's ability to attract and retain employees; the Company's ability to satisfy pension and other postretirement employee benefit obligations; changes in accounting standards; the effect of labor strikes, lockouts and labor negotiations; regulatory and judicial rulings; the Company's indebtedness and ability to comply with debt covenants applicable to its debt facilities; the Company's ability to satisfy future capital and liquidity requirements; the Company's ability to access the credit and capital markets at the times and in the amounts needed and on acceptable terms; and other events beyond the Company's control that may result in unexpected adverse operating results.

For example, the expected timing and likelihood of completion of the proposed merger, including the timing, receipt and terms and conditions of any required governmental and regulatory approvals of the proposed merger that could reduce anticipated benefits or cause the parties to abandon the transaction, the ability to successfully integrate the businesses, the occurrence of any event, change or other circumstances that could give rise to the termination of the merger agreement, the possibility that Kraft shareholders may not approve the merger agreement, the risk that the parties may not be able to satisfy the conditions to the proposed transaction in a timely manner or at all, risks related to disruption of management time from ongoing business operations due to the proposed transaction, the risk that any announcements relating to the proposed transaction could have adverse effects on the market price of Kraft's common stock, and the risk that the proposed transaction and its announcement could have an adverse effect on the ability of Kraft and Heinz to retain customers and retain and hire key personnel and maintain relationships with their suppliers and customers and on their operating results and businesses generally, problems may arise in successfully integrating the businesses of the companies, which may result in the combined company not operating as effectively and efficiently as expected, the combined company may be unable to achieve cost - cutting synergies or it may take longer than expected to achieve those synergies, and other factors.

As a result, political instability, labor strikes, natural disasters or other events resulting in the disruption of trade or transportation from other countries or the imposition of additional regulations relating to duties upon imports could cause significant delays or interruptions in the supply of our merchandise or increase our costs, either of which could have an adverse effect on our business.

«There are a lot of people taking statins who are not getting any benefits from them, and they're subject to a lot of adverse events,» Redberg says.

Bress is the lead author of «Potential Deaths Averted and Serious Adverse Events from the adoption of the SPRINT Intensive Blood Pressure Regiment in the U.S.» which publishes online on Feb. 13 in the journal, Circulation.

«Some may question the reliability of these data because the adverse events were determined and classified by investigators from the pharmaceutical company,» Emanuel said.

At AAP, Dr. Roy also presented an analysis of adverse drug events (ADE) among hospitalized children in the U.S. from 2003 to 2010.

Patients with multiple health issues and who are at higher risk of adverse events are less likely to receive follow - up care from a physician after visiting an emergency department for chest pain, reports a study published in CMAJ (Canadian Medical Association Journal)

The researchers were unsure whether the high diversity of leaf miners at Mexican Hat compared to other early Paleocene sites, where there is little or no leaf mining, was caused by insects that survived the extinction event in refugia — areas where organisms persist during adverse conditions — or were due to range expansions of insects from somewhere else during the early Paleocene.

«As two organizations committed to the health and safety of workers, it makes sense for us to address the potential consequences of workforce marijuana use on employers, ranging from the risk and associated cost of adverse events to the possible loss of productivity,» said AAOHN President Jeannie Tomlinson.

Over a 10 - year period, from 2006 to 2016, the FDA collected reports of «adverse events» in more than 370 children who had used Hyland's homeopathic teething tablets or gel, a similar product that is applied directly to a baby's gums.

Analysis showed there were 5,144 adverse events submitted from 2004 to 2016, an average of 396 events per year.

«Although previous studies of non-surgical weight loss interventions failed to show consistent results regarding asthma risks, our result strongly suggests that the kind of significant weight loss that often results from bariatric surgery can reduce adverse asthma events.»

Limitations of the study include that causality of adverse events can not be determined from the data, health outcomes are self - reported and reports from consumers vs. health care professionals can not be distinguished.

Only one woman reported an episode of drowsiness from the sham acupuncture, whereas the placebo pill recipients reported eight adverse events such as headache, fatigue, dizziness and constipation.

«There was no analysis of all critical parameters and critical processing steps to try to determine differences in the 2010 lots associated with Adverse Event reports compared to lots from previous seasons» the letter states.

The researchers found that U.S. women bear the brunt — roughly 60 % — of the adverse health events and DALYs resulting from sex.

Combining information from multiple U.S. data sources, researchers found that mothers with preeclampsia and their infants were at a significantly increased risk for adverse health events compared to mothers without preeclampsia (increased 4.6 % to 10.1 % in mothers and 7.8 % to 15.4 % in infants within 12 months of childbirth).

In conclusion, Dr. Schadendorf said that «even though the nivolumab plus ipilimumab arm had a higher frequency of adverse events, no clinically meaningful health - related QoL changes from baseline were observed in any of the treatment arms.

It turns out that those who have family members who have experienced trauma or adverse life events may have a lower threshold for emotional pain and a higher likelihood of suffering from stress or mood disorders.

The limited reports of complications arising from use of the modified Atkins diet (MAD) or low glycaemic index treatment suggest fewer and less serious adverse events when these more liberal modified diets are used (32, 33, 34, 35), although a prospective review of 6 MAD studies found 13 % of 92 children and adults discontinued the diet due to intolerance or side effects (36).

History of safe traditional use No case reports of significant adverse events with high probability of causality No significant adverse events in clinical trials No identified concerns for use during pregnancy or lactation No innately toxic constituents Toxicity associated with excessive use is not a basis for exclusion from this class Minor or self - limiting side effects are not bases for exclusion from this class»

Over the period 2008 to 2011, the Government Accountability Office (GAO) of the United States received 6,307 reports of health problems (identified as adverse events) from use of dietary supplements containing a combination of ingredients in manufactured vitamins, minerals or other supplement products, [72] with 92 % of tested herbal supplements containing lead and 80 % containing other chemical contaminants.

«Much work has already shown adverse outcomes from too much saturated fat in the diet, in addition to the development of diabetes, heart disease, and other cardiovascular events.

... and many studies have been found that show that, at least for a short period of time, damage from glycation and other adverse molecular events occur with far lower blood glucose.

Adverse weather prevented several school groups from seeing performances of A Christmas Carol, and we have treated those events as exogenous and assigned those groups to the control group.

Such statements reflect the current views of Barnes & Noble with respect to future events, the outcome of which is subject to certain risks, including, among others, the general economic environment and consumer spending patterns, decreased consumer demand for Barnes & Noble's products, low growth or declining sales and net income due to various factors, possible disruptions in Barnes & Noble's computer systems, telephone systems or supply chain, possible risks associated with data privacy, information security and intellectual property, possible work stoppages or increases in labor costs, possible increases in shipping rates or interruptions in shipping service, effects of competition, possible risks that inventory in channels of distribution may be larger than able to be sold, possible risks associated with changes in the strategic direction of the device business, including possible reduction in sales of content, accessories and other merchandise and other adverse financial impacts, possible risk that component parts will be rendered obsolete or otherwise not be able to be effectively utilized in devices to be sold, possible risk that financial and operational forecasts and projections are not achieved, possible risk that returns from consumers or channels of distribution may be greater than estimated, the risk that digital sales growth is less than expectations and the risk that it does not exceed the rate of investment spend, higher - than - anticipated store closing or relocation costs, higher interest rates, the performance of Barnes & Noble's online, digital and other initiatives, the success of Barnes & Noble's strategic investments, unanticipated increases in merchandise, component or occupancy costs, unanticipated adverse litigation results or effects, product and component shortages, the potential adverse impact on the Company's businesses resulting from the Company's prior reviews of strategic alternatives and the potential separation of the Company's businesses, the risk that the transactions with Microsoft and Pearson do not achieve the expected benefits for the parties or impose costs on the Company in excess of what the Company anticipates, including the risk that NOOK Media's applications are not commercially successful or that the expected distribution of those applications is not achieved, risks associated with the international expansion contemplated by the relationship with Microsoft, including that it is not successful or is delayed, the risk that NOOK Media is not able to perform its obligations under the Microsoft and Pearson commercial agreements and the consequences thereof, risks associated with the restatement contained in, the delayed filing of, and the material weakness in internal controls described in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 27, 2013, risks associated with the SEC investigation disclosed in the quarterly report on Form 10 - Q for the fiscal quarter ended October 26, 2013, risks associated with the ongoing efforts to rationalize the NOOK business and the expected costs and benefits of such efforts and associated risks and other factors which may be outside of Barnes & Noble's control, including those factors discussed in detail in Item 1A, «Risk Factors,» in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 27, 2013, and in Barnes & Noble's other filings made hereafter from time to time with the SEC.

Such statements reflect the current views of Barnes & Noble with respect to future events, the outcome of which is subject to certain risks, including, among others, the effect of the proposed separation of NOOK Media, the general economic environment and consumer spending patterns, decreased consumer demand for Barnes & Noble's products, low growth or declining sales and net income due to various factors, possible disruptions in Barnes & Noble's computer systems, telephone systems or supply chain, possible risks associated with data privacy, information security and intellectual property, possible work stoppages or increases in labor costs, possible increases in shipping rates or interruptions in shipping service, effects of competition, possible risks that inventory in channels of distribution may be larger than able to be sold, possible risks associated with changes in the strategic direction of the device business, including possible reduction in sales of content, accessories and other merchandise and other adverse financial impacts, possible risk that component parts will be rendered obsolete or otherwise not be able to be effectively utilized in devices to be sold, possible risk that financial and operational forecasts and projections are not achieved, possible risk that returns from consumers or channels of distribution may be greater than estimated, the risk that digital sales growth is less than expectations and the risk that it does not exceed the rate of investment spend, higher - than - anticipated store closing or relocation costs, higher interest rates, the performance of Barnes & Noble's online, digital and other initiatives, the success of Barnes & Noble's strategic investments, unanticipated increases in merchandise, component or occupancy costs, unanticipated adverse litigation results or effects, product and component shortages, risks associated with the commercial agreement with Samsung, the potential adverse impact on the Company's businesses resulting from the Company's prior reviews of strategic alternatives and the potential separation of the Company's businesses (including with respect to the timing of the completion thereof), the risk that the transactions with Pearson and Samsung do not achieve the expected benefits for the parties or impose costs on the Company in excess of what the Company anticipates, including the risk that NOOK Media's applications are not commercially successful or that the expected distribution of those applications is not achieved, risks associated with the international expansion previously undertaken, including any risks associated with a reduction of international operations following termination of the Microsoft commercial agreement, the risk that NOOK Media is not able to perform its obligations under the Pearson and Samsung commercial agreements and the consequences thereof, the risks associated with the termination of Microsoft commercial agreement, including potential customer losses, risks associated with the restatement contained in, the delayed filing of, and the material weakness in internal controls described in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 27, 2013, risks associated with the SEC investigation disclosed in the quarterly report on Form 10 - Q for the fiscal quarter ended October 26, 2013, risks associated with the ongoing efforts to rationalize the NOOK business and the expected costs and benefits of such efforts and associated risks and other factors which may be outside of Barnes & Noble's control, including those factors discussed in detail in Item 1A, «Risk Factors,» in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended May 3, 2014, and in Barnes & Noble's other filings made hereafter from time to time with the SEC.

Such statements reflect the current views of Barnes & Noble with respect to future events, the outcome of which is subject to certain risks, including, among others, the general economic environment and consumer spending patterns, decreased consumer demand for Barnes & Noble's products, low growth or declining sales and net income due to various factors, including store closings, higher - than - anticipated or increasing costs, including with respect to store closings, relocation, occupancy (including in connection with lease renewals) and labor costs, the effects of competition, the risk of insufficient access to financing to implement future business initiatives, risks associated with data privacy and information security, risks associated with Barnes & Noble's supply chain, including possible delays and disruptions and increases in shipping rates, various risks associated with the digital business, including the possible loss of customers, declines in digital content sales, risks and costs associated with ongoing efforts to rationalize the digital business and the digital business not being able to perform its obligations under the Samsung commercial agreement and the consequences thereof, the risk that financial and operational forecasts and projections are not achieved, the performance of Barnes & Noble's initiatives including but not limited to its new store concept and e-commerce initiatives, unanticipated adverse litigation results or effects, potential infringement of Barnes & Noble's intellectual property by third parties or by Barnes & Noble of the intellectual property of third parties, and other factors, including those factors discussed in detail in Item 1A, «Risk Factors,» in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 30, 2016, and in Barnes & Noble's other filings made hereafter from time to time with the SEC.

Homeowner's insurance is important because it covers issues that arise from fires, tornadoes, theft and other types of adverse events.

Life insurance riders supplement your term life policy with more coverage by offering additional protection from the potential loss of income due to terminal illness, disability, or other adverse life events.

Researchers (Moore, Guptill, Ward et al, «Adverse events diagnosed within three days of vaccine administration in dogs») looked at veterinary records gathered from Banfield veterinary clinics for two years to find any trends in reactions suffered three days after vaccination.

The National Animal Supplement Council responsibly records both Adverse Events and Serious Adverse Events resulting from the use of natural products.

In 2009, the U.S. Environmental Protection Agency (EPA) reported adverse reactions from flea & tick control products had doubled since 2005 — mainly due to misapplication.1 After an extensive evaluation of all flea & tick products, the EPA found most adverse drug events were minor, but there were major incidents, too.

Journal of the American Veterinary Medical Association - Adverse events diagnosed within three days of vaccine administration in dogs study of more than 2,000 cats and dogs in the United Kingdom by Canine Health Concern showed a 1 in 10 risk of adverse reactions from vaAdverse events diagnosed within three days of vaccine administration in dogs study of more than 2,000 cats and dogs in the United Kingdom by Canine Health Concern showed a 1 in 10 risk of adverse reactions from vaadverse reactions from vaccines.

Manufacturers of spot - on flea - and - tick products have six months to make labeling changes, according to a new directive from the Environmental Protection Agency, to address increasing adverse events associated with the misapplication of these products by pet owners.

At least two municipal governments reassured investors that they were «unable to predict whether sea - level rise or other impacts of climate change or flooding from a major storm will occur, when they may occur, and if any such events occur, whether they will have a material adverse effect...»» (emphasis added)

As discussed earlier, Hurricane Katrina demonstrated that communities of color, poor communities, and certain other vulnerable populations (like new immigrant communities) are at a higher risk to the adverse effects of extreme weather events.263, 264,239 These vulnerable populations could benefit from urban planning policies that ensure that new buildings, including homes, are constructed to resist extreme weather events.303

A 2017 disclosure by San Francisco reads: «The city is unable to predict whether sea level rise or other impacts of climate change or flooding from a major storm will occur, when they may occur, and if any such events occur, whether they will have a material adverse effect on the business operations or financial condition of the city and the local economy.»

Loss and Damage encompasses how to deal with the adverse impacts of extreme weather events and slow onset events, and the economic and non-economic losses and damages suffered from them, those impacts that can not be recuperated either through mitigating or adapting.

Even with warming of 2 °C, we can expect to see adverse effects on water availability in critical river basins, a more than doubling of forest fires in Amazonia by 2050, impacted coral reef recovery from bleaching events, among other effects.

It has been assumed that what you can't hear can't hurt you — the findings in the NIEHS literature review would suggest otherwise, as would Professor Alec Salt's work (see www.wind-watch.org/documents/responses-of-the-ear-to-low-frequency-sounds-infrasound-and-wind-turbines/), and the thousands of adverse health event reports from people living with industrial wind turbines around the world.

«By planting trees in coffee farms,» explains Jérôme Perez, head of sustainability at Nespresso, «you are protecting the coffee bushes from heavy rain, and we know that adverse weather events impact a lot on the production of Arabica coffee in the last few years in Colombia.

Unlike other pre-emptive costs orders (such as costs capping orders), their aim is not solely to control extravagant expenditure; instead, their aim is to protect litigants who reasonably bring public law proceedings in the public interest from the liability of an adverse costs order in the event that they lose.

These sessions, along with the industry - leading keynotes and hands - on training, will teach attendees from across the globe how to break down the barriers between legal, compliance, and operational risk - reducing the impact of adverse events with transparency, predictability, and control.