Sentences with phrase «of adverse outcomes associated»

Despite the link that has been reported widely in the literature between poor vision and quality of life outcomes, older adults are not uniform in their experience of adverse outcomes associated with poor vision.

«When one considers the modest decrease in risk of adverse outcomes associated with the use of a number of widely used medications such as anti-cholesterol drugs, the effect sizes seen in this study are really impressive,» said Dr. Memtsoudis.

Not exact matches

Helping adolescent males to delay fatherhood may also be important from a child health perspective: research that controlled for maternal age and other key factors found teenage fatherhood associated with an increased risk of adverse pregnancy outcomes, including preterm birth, low birth weight and neonatal death (Chen et al, 2007).

Her research portfolio includes findings that suggest disparities in adverse pregnancy outcomes begin as early as conception, multivitamin use around the time of conception prevents some miscarriages, over-the-counter use of non-steroidal anti-inflammatory agents is not a probable cause of miscarriage (and may be protective in some women), and the vast majority of uterine fibroids are not associated with adverse pregnancy outcomes including miscarriage and preterm birth, though fibroids are related to a moderately higher likelihood of cesarean.

For nulliparous women, there is some evidence that planning birth at home is associated with a higher risk of an adverse perinatal outcome.

Discontinuation of epidural analgesia late in labour for reducing the adverse delivery outcomes associated with epidural analgesia.

Rates of obstetrical intervention are high in U.S. hospitals, and we found large absolute differences in the risks of these interventions between planned out - of - hospital births and in - hospital births.38 In contrast, serious adverse fetal and neonatal outcomes are infrequent in all the birth settings we assessed, and the absolute differences in risk that we observed between planned birth locations were correspondingly small; for example, planned out - of - hospital births were associated with an excess of less than 1 fetal death per 1000 deliveries in multivariate and propensity - score - adjusted analyses.

Labor induction has been increasing since the early 1990s, 1 and the rate is running at about 20 % for pregnancies at term.2, 3 Induction of labor compared with spontaneous labor is associated with adverse maternal outcomes, including at least a doubling in the caesarean delivery rate, 4,5 25 — 50 % increase in instrumental vaginal delivery rate, 3,5 higher postpartum hemorrhage rate, 5 and prolonged labor.5 Neonates born after induced labor are more likely to have low Apgar score and low umbilical cord blood pH. 5

In analyses adjusted for maternal race and ethnic group, age, parity, and medical conditions associated with greater risk, the associations between planned location of delivery and most adverse outcomes and obstetrical procedures remained significant (Table 4).

Planned birth at home in low risk women without complicating conditions at the start of care in labour was associated with significant cost savings and a significant decrease in adverse perinatal outcomes avoided.

There was, however, an increased incidence of adverse perinatal outcome associated with planned birth at home in nulliparous low risk women, resulting in the probability of it being the most cost effective option at a cost effectiveness threshold of # 20000 declining to 0.63.

We used multiple regression to estimate the differences in total cost between the settings for birth and to adjust for potential confounders, including maternal age, parity, ethnicity, understanding of English, marital status, BMI, index of multiple deprivation score, parity, and gestational age at birth, which could each be associated with planned place of birth and with adverse outcomes.12 For the generalised linear model on costs, we selected a γ distribution and identity link function in preference to alternative distributional forms and link functions on the basis of its low Akaike's information criterion (AIC) statistic.

Nevertheless, «travel times greater than 20 minutes [to a healthcare facility] have been associated with increased risk of adverse neonatal outcomes, including mortality.»

There was, however, an increased incidence of adverse perinatal outcomes associated with planned birth at home in nulliparous low risk women, resulting in the probability of it being the most cost effective option at a threshold of # 20000 declining to 0.63.

This cost effectiveness information, however, should be considered in the light of an increased risk of adverse perinatal outcome associated with planned home birth in low risk nulliparous women.

There does not appear to be an associated increased risk of adverse maternal, fetal, or neonatal outcomes.

In the era of electronic fetal monitoring, among neonates born to nulliparous women, adverse neonatal outcomes generally have not been associated with the duration of the second stage of labor.

Similarly, in a secondary analysis of 1,862 women enrolled in an early versus delayed pushing trial, a longer duration of active pushing was not associated with adverse neonatal outcomes, even in women who pushed for more than 3 hours (28).

Enabling women to breastfeed is also a public health priority because, on a population level, interruption of lactation is associated with adverse health outcomes for the woman and her child, including higher maternal risks of breast cancer, ovarian cancer, diabetes, hypertension, and heart disease, and greater infant risks of infectious disease, sudden infant death syndrome, and metabolic disease (2, 4).

Planned home births attended by registered professional attendants have not been associated with an increased risk of adverse perinatal outcomes in large studies in North America, 1 — 3 the United Kingdom, 4 Europe, 5 — 8 Australia 9 and New Zealand.

Our study showed that planned home birth attended by a registered midwife was associated with very low and comparable rates of perinatal death and reduced rates of obstetric interventions and adverse maternal outcomes compared with planned hospital birth attended by a midwife or physician.

Overall, we did not find any increased likelihood for any adverse outcome for women or their infants associated with having been randomised to a midwife - led continuity model of care.

«Mothers of infants with complex congenital heart disease are exposed to increased stress, which has been associated with numerous adverse outcomes,» said Barbara Medoff - Cooper, PhD, RN FAAN, principal investigator and nurse scientist in the Cardiac Center at Children's Hospital of Philadelphia and at Penn Nursing.

In the article, Stamatina Iliodromiti from the University of Glasgow, UK, and colleagues found birth weight less than 25th or greater than 85th centile to be associated with greater risk of adverse outcomes compared with birth weight within these cutoffs, suggesting an expansion of the definition of «fetus at risk» beyond the less than 10th or greater than 90th centile range that is commonly used to trigger surveillance of fetal well - being and / or delivery.

A review of studies investigating the 2008 recession in Europe show it was associated with adverse health outcomes, particularly for suicides and mental health problems, finds a study in The BMJ.

«Our results suggest that exposure to higher levels of air pollution during pregnancy is associated with various adverse pregnancy outcomes,» said Prof. Lerner - Geva.

High levels of two novel urinary biomarkers early in critical illness are associated with adverse long - term outcomes in patients with acute kidney injury (AKI), according to an international, multi-center study led by University of Pittsburgh School of Medicine Researchers.

«The results of this study were of particular interest because more than half of the pregnant women with migraine experienced some type of adverse birth outcome, suggesting that these pregnancies should be considered high risk,» said study author Matthew S. Robbins, M.D., director of inpatient services at Montefiore Headache Center, chief of neurology at Jack D. Weiler Hospital of Montefiore, and associate professor of clinical neurology at Albert Einstein College of Medicine.

«Our goal is to raise overall awareness of military sexual trauma, including the impact on male veterans, and associated adverse outcomes such as homelessness,» Kimerling says.

There is evidence that rTMS is safe and not associated with any adverse events, but given the variability in technique and outcome reporting that prevented meta - analysis, the evidence for efficacy of rTMS for seizure reduction is still lacking despite reasonable evidence that it is effective at reducing epileptiform discharges.

«Our study finds that our assumptions of «care neutrality» may be wrong and that, among adults undergoing major surgery, complete handover of intraoperative anesthesia care compared with no handover was associated with a higher risk of adverse postoperative outcomes.

«This is one of the largest studies to have examined the adverse mental health and neurodevelopmental outcomes associated with PCOS, and we hope the results will lead to increased awareness, earlier detection and new treatments,» Rees said in a journal news release.

A high level of caffeine intake was associated with risk factors for adverse reproductive outcomes.

Such statements reflect the current views of Barnes & Noble with respect to future events, the outcome of which is subject to certain risks, including, among others, the general economic environment and consumer spending patterns, decreased consumer demand for Barnes & Noble's products, low growth or declining sales and net income due to various factors, possible disruptions in Barnes & Noble's computer systems, telephone systems or supply chain, possible risks associated with data privacy, information security and intellectual property, possible work stoppages or increases in labor costs, possible increases in shipping rates or interruptions in shipping service, effects of competition, possible risks that inventory in channels of distribution may be larger than able to be sold, possible risks associated with changes in the strategic direction of the device business, including possible reduction in sales of content, accessories and other merchandise and other adverse financial impacts, possible risk that component parts will be rendered obsolete or otherwise not be able to be effectively utilized in devices to be sold, possible risk that financial and operational forecasts and projections are not achieved, possible risk that returns from consumers or channels of distribution may be greater than estimated, the risk that digital sales growth is less than expectations and the risk that it does not exceed the rate of investment spend, higher - than - anticipated store closing or relocation costs, higher interest rates, the performance of Barnes & Noble's online, digital and other initiatives, the success of Barnes & Noble's strategic investments, unanticipated increases in merchandise, component or occupancy costs, unanticipated adverse litigation results or effects, product and component shortages, the potential adverse impact on the Company's businesses resulting from the Company's prior reviews of strategic alternatives and the potential separation of the Company's businesses, the risk that the transactions with Microsoft and Pearson do not achieve the expected benefits for the parties or impose costs on the Company in excess of what the Company anticipates, including the risk that NOOK Media's applications are not commercially successful or that the expected distribution of those applications is not achieved, risks associated with the international expansion contemplated by the relationship with Microsoft, including that it is not successful or is delayed, the risk that NOOK Media is not able to perform its obligations under the Microsoft and Pearson commercial agreements and the consequences thereof, risks associated with the restatement contained in, the delayed filing of, and the material weakness in internal controls described in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 27, 2013, risks associated with the SEC investigation disclosed in the quarterly report on Form 10 - Q for the fiscal quarter ended October 26, 2013, risks associated with the ongoing efforts to rationalize the NOOK business and the expected costs and benefits of such efforts and associated risks and other factors which may be outside of Barnes & Noble's control, including those factors discussed in detail in Item 1A, «Risk Factors,» in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 27, 2013, and in Barnes & Noble's other filings made hereafter from time to time with the SEC.

Such statements reflect the current views of Barnes & Noble with respect to future events, the outcome of which is subject to certain risks, including, among others, the effect of the proposed separation of NOOK Media, the general economic environment and consumer spending patterns, decreased consumer demand for Barnes & Noble's products, low growth or declining sales and net income due to various factors, possible disruptions in Barnes & Noble's computer systems, telephone systems or supply chain, possible risks associated with data privacy, information security and intellectual property, possible work stoppages or increases in labor costs, possible increases in shipping rates or interruptions in shipping service, effects of competition, possible risks that inventory in channels of distribution may be larger than able to be sold, possible risks associated with changes in the strategic direction of the device business, including possible reduction in sales of content, accessories and other merchandise and other adverse financial impacts, possible risk that component parts will be rendered obsolete or otherwise not be able to be effectively utilized in devices to be sold, possible risk that financial and operational forecasts and projections are not achieved, possible risk that returns from consumers or channels of distribution may be greater than estimated, the risk that digital sales growth is less than expectations and the risk that it does not exceed the rate of investment spend, higher - than - anticipated store closing or relocation costs, higher interest rates, the performance of Barnes & Noble's online, digital and other initiatives, the success of Barnes & Noble's strategic investments, unanticipated increases in merchandise, component or occupancy costs, unanticipated adverse litigation results or effects, product and component shortages, risks associated with the commercial agreement with Samsung, the potential adverse impact on the Company's businesses resulting from the Company's prior reviews of strategic alternatives and the potential separation of the Company's businesses (including with respect to the timing of the completion thereof), the risk that the transactions with Pearson and Samsung do not achieve the expected benefits for the parties or impose costs on the Company in excess of what the Company anticipates, including the risk that NOOK Media's applications are not commercially successful or that the expected distribution of those applications is not achieved, risks associated with the international expansion previously undertaken, including any risks associated with a reduction of international operations following termination of the Microsoft commercial agreement, the risk that NOOK Media is not able to perform its obligations under the Pearson and Samsung commercial agreements and the consequences thereof, the risks associated with the termination of Microsoft commercial agreement, including potential customer losses, risks associated with the restatement contained in, the delayed filing of, and the material weakness in internal controls described in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 27, 2013, risks associated with the SEC investigation disclosed in the quarterly report on Form 10 - Q for the fiscal quarter ended October 26, 2013, risks associated with the ongoing efforts to rationalize the NOOK business and the expected costs and benefits of such efforts and associated risks and other factors which may be outside of Barnes & Noble's control, including those factors discussed in detail in Item 1A, «Risk Factors,» in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended May 3, 2014, and in Barnes & Noble's other filings made hereafter from time to time with the SEC.

Such statements reflect the current views of Barnes & Noble with respect to future events, the outcome of which is subject to certain risks, including, among others, the general economic environment and consumer spending patterns, decreased consumer demand for Barnes & Noble's products, low growth or declining sales and net income due to various factors, including store closings, higher - than - anticipated or increasing costs, including with respect to store closings, relocation, occupancy (including in connection with lease renewals) and labor costs, the effects of competition, the risk of insufficient access to financing to implement future business initiatives, risks associated with data privacy and information security, risks associated with Barnes & Noble's supply chain, including possible delays and disruptions and increases in shipping rates, various risks associated with the digital business, including the possible loss of customers, declines in digital content sales, risks and costs associated with ongoing efforts to rationalize the digital business and the digital business not being able to perform its obligations under the Samsung commercial agreement and the consequences thereof, the risk that financial and operational forecasts and projections are not achieved, the performance of Barnes & Noble's initiatives including but not limited to its new store concept and e-commerce initiatives, unanticipated adverse litigation results or effects, potential infringement of Barnes & Noble's intellectual property by third parties or by Barnes & Noble of the intellectual property of third parties, and other factors, including those factors discussed in detail in Item 1A, «Risk Factors,» in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 30, 2016, and in Barnes & Noble's other filings made hereafter from time to time with the SEC.

In this instance, however, the overall weight of the evidence from the cumulative body of information contained in this Public Health Review demonstrates that there are significant uncertainties about the kinds of adverse health outcomes that may be associated with HVHF, the likelihood of the occurrence of adverse health outcomes, and the effectiveness of some of the mitigation measures in reducing or preventing environmental impacts which could adversely affect public health.

BACKGROUND: Ultrafine particles (UFPs) have been associated with adverse health outcomes in children, but studies are often limited by surrogate estimates of exposure.

Exposure to adverse early - life environments is associated with a range of negative developmental outcomes, including poor mental and physical health and atypical social functioning.

Our findings add insight into the pathways linking early childhood adversity to poor adult wellbeing.29 Complementing past work that focused on physical health, 9 our findings provide information about links between ACEs and early childhood outcomes at the intersection of learning, behavior, and health.29 We found that ACEs experienced in early childhood were associated with poor foundational skills, such as language and literacy, that predispose individuals to low educational attainment and adult literacy, both of which are related to poor health.23, 30 — 33 Attention problems, social problems, and aggression were also associated with ACEs and also have the potential to interfere with children's educational experience given known associations between self - regulatory behavior and academic achievement.34, 35 Consistent with the original ACE study and subsequent research, we found that exposure to more ACEs was associated with more adverse outcomes, suggesting a dose — response association.3 — 8 In fact, experiencing ≥ 3 ACEs was associated with below - average performance or problems in every outcome examined.

Cannabis use can be a significant contributor to poor mental health, particularly when it begins at a young age.4, 5 The adverse mental health effects of cannabis use in the general population are increasingly recognised, including anxiety, depression, 6 — 8 psychotic disorders, 4, 9 — 12 dependence6, 7, 13 withdrawal14, 15 and cognitive impairment.16, 17 Starting to use cannabis before age 15 is associated with an increased likelihood of developing later psychotic disorders, increased risk of dependence, other drug use, and poor educational and psychosocial outcomes.5

Relative to children with no ACEs, children who experienced ACEs had increased odds of having below - average academic skills including poor literacy skills, as well as attention problems, social problems, and aggression, placing them at significant risk for poor school achievement, which is associated with poor health.23 Our study adds to the growing literature on adverse outcomes associated with ACEs3 — 9,24 — 28 by pointing to ACEs during early childhood as a risk factor for child academic and behavioral problems that have implications for education and health trajectories, as well as achievement gaps and health disparities.

The higher risk for maternal postpartum depression is also associated with reduced parenting skills, which may have negative consequences for the development of the child.28 — 30 Parents of obese children may lack effective parenting skills providing both a consistent structured frame and emotional support.31 In women with GDM, psychosocial vulnerability including low levels of social and family networks is associated with more adverse neonatal outcomes, especially increased birth weight.32 Thus, there is a tight interaction between maternal lifestyle, weight status, mental health, social support as well as between maternal and child's overall health.

Recent examinations into the outcomes of childhood trauma have resulted in findings that demonstrate the notion that extreme childhood adversity is not only linked to undesirable juvenile and adult behaviors, but that there is also an intergenerational risk factor associated with adverse experiences at a young age (e.g., Bifulco et al., 2002; Chartier, Walker, & Naimark, 2010; Felitti et al., 1998; Gregorowski & Seedat, 2013; Mersky, Topitzes, & Reynolds, 2013; Sameroff, 2000).

Thus, adverse outcomes associated with ACE exposure begin in early childhood and impact multiple aspects of children's lives.

Maternal glucose at 28 weeks of gestation is not associated with obesity in 2 - year - old offspring: the Belfast Hyperglycemia and Adverse Pregnancy Outcome (HAPO) family study

Perinatal depression is common; in high - income countries the point prevalence is approximately 13 %, with higher rates estimated in low - income and middle - income countries.1 Furthermore, perinatal depression is associated with an increased risk of adverse child outcomes, including behavioural, emotional and cognitive difficulties, 2 which persist into late childhood and adolescence.

Small size at birth is associated with a range of adverse health outcomes, 1 including poor cognitive development, 2 an effect that is largely unconfounded by features of the family environment, such as socioeconomic status and birth order.

Depression is known to be associated with adverse outcomes, including non-adherence with advice and poorer quality of life.

We chose to use characteristics used for sample recruitment as indicators of long - term stress (eg, coming from a low - SES household) and having few personal resources (eg, being unmarried), 2 factors associated with a host of adverse outcomes.