Sentences with phrase «of adverse outcomes for»

The hospital's early recognition and treatment of sepsis resulted in a 30 % reduced risk of adverse outcomes for sepsis and severe sepsis patients, such as death or discharge to hospice.

Dr. Fisher believes that dispassionate, rigorous study of birth across all settings is more important than ever given disparities in women's access to trained and licensed care providers, current and future physician workforce issues, rising costs of health care, and unacceptably high rates of adverse outcomes for mothers and infants in the U.S. compared to other industrialized countries.

Explain that if they plan birth at home there is a small increase in the risk of an adverse outcome for the baby.

According to new research published in the Journal of Clinical Endocrinology and Metabolism, the current policy of limiting thyroid tests to women at high risk of thyroid disease overlooks most cases of thyroid disease during pregnancy, and undiagnosed, untreated thyroid disease in pregnancy carries a significant risk of an adverse outcome for both mother and baby.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

We regularly assess the likelihood of adverse outcomes resulting from these examinations to determine the adequacy of our provision for income taxes.

I counter: To insist the general risk pool (etc) pay for your first birth without medical resources present, in spite of the fact that same risk pool will still be responsible for caring for any adverse outcomes due to lack of medical resources is hypocritical beyond belief.

Helping adolescent males to delay fatherhood may also be important from a child health perspective: research that controlled for maternal age and other key factors found teenage fatherhood associated with an increased risk of adverse pregnancy outcomes, including preterm birth, low birth weight and neonatal death (Chen et al, 2007).

Tough summarizes key research, such as the Adverse Childhood Experience Study, a project of the Centers for Disease Control and Kaiser Permanente, which revealed a stunning correlation between traumatic childhood events and negative adult outcomes.

For healthy nulliparous women with a low risk pregnancy, the risk of an adverse perinatal outcome seems to be higher for planned births at home, and the intrapartum transfer rate is high in all settings other than an obstetric uFor healthy nulliparous women with a low risk pregnancy, the risk of an adverse perinatal outcome seems to be higher for planned births at home, and the intrapartum transfer rate is high in all settings other than an obstetric ufor planned births at home, and the intrapartum transfer rate is high in all settings other than an obstetric unit

For healthy women with low risk pregnancies, the incidence of adverse perinatal outcomes is low in all birth settings

«Women with planned home birth had lower rates of all adverse maternal outcomes, albeit not significantly so for nulliparous women.»

Regulating it, using better trained practitioners and proper guidelines for risking - out and transfer definitely would reduce the rate of adverse outcomes.

For nulliparous women, there is some evidence that planning birth at home is associated with a higher risk of an adverse perinatal outcome.

The strengths of the study include the ability to compare outcomes by the woman's planned place of birth at the start of care in labour, the high participation of midwifery units and trusts in England, the large sample size and statistical power to detect clinically important differences in adverse perinatal outcomes, the minimisation of selection bias through achievement of a high response rate and absence of self selection bias due to non-consent, the ability to compare groups that were similar in terms of identified clinical risk (according to current clinical guidelines) and to further increase the comparability of the groups by conducting an additional analysis restricted to women with no complicating conditions identified at the start of care in labour, and the ability to control for several important potential confounders.

Discontinuation of epidural analgesia late in labour for reducing the adverse delivery outcomes associated with epidural analgesia.

Tanaka K, Yamada H, Minami M, Kataoka S, Numazaki K, Minakami H, Tsutsumi H. «Screening for vaginal shedding of cytomegalovirus in healthy pregnant women using real - time PCR: correlation of CMV in the vagina and adverse outcome of pregnancy.»

A 2014 study that examines nearly 17,000 courses of midwife - led care confirms that among low - risk women, home births result in low rates of interventions without an increase in adverse outcomes for babies and mothers alike.

The tradeoff between the additional physical safety conferred by a hospital setting in the case of an adverse outcome, and the emotional comfort of being in a familiar environment, is sufficient for her.

The study reviewed the births of nearly 17,000 women and found that, among low - risk women, planned home births result in low rates of birth interventions without an increase in adverse outcomes for mothers and newborns.

We categorized out - of - hospital and in - hospital births in Oregon according to the intended place of delivery and in comparing outcomes found that the risks for some adverse neonatal outcomes were increased among planned out - of - hospital births.

Rates of obstetrical intervention are high in U.S. hospitals, and we found large absolute differences in the risks of these interventions between planned out - of - hospital births and in - hospital births.38 In contrast, serious adverse fetal and neonatal outcomes are infrequent in all the birth settings we assessed, and the absolute differences in risk that we observed between planned birth locations were correspondingly small; for example, planned out - of - hospital births were associated with an excess of less than 1 fetal death per 1000 deliveries in multivariate and propensity - score - adjusted analyses.

For example, the Dutch home - birth system (in which home birth is common and adverse outcomes are rare) includes formal collaborative agreements between out - of - hospital and in - hospital providers, clear and mutually agreed - upon stratification of risk, and protocols for the transfer of care.35, 36 The process of devising evidence - based guidelines for U.S. home births is under wayFor example, the Dutch home - birth system (in which home birth is common and adverse outcomes are rare) includes formal collaborative agreements between out - of - hospital and in - hospital providers, clear and mutually agreed - upon stratification of risk, and protocols for the transfer of care.35, 36 The process of devising evidence - based guidelines for U.S. home births is under wayfor the transfer of care.35, 36 The process of devising evidence - based guidelines for U.S. home births is under wayfor U.S. home births is under way.37

Labor induction has been increasing since the early 1990s, 1 and the rate is running at about 20 % for pregnancies at term.2, 3 Induction of labor compared with spontaneous labor is associated with adverse maternal outcomes, including at least a doubling in the caesarean delivery rate, 4,5 25 — 50 % increase in instrumental vaginal delivery rate, 3,5 higher postpartum hemorrhage rate, 5 and prolonged labor.5 Neonates born after induced labor are more likely to have low Apgar score and low umbilical cord blood pH. 5

In analyses adjusted for maternal race and ethnic group, age, parity, and medical conditions associated with greater risk, the associations between planned location of delivery and most adverse outcomes and obstetrical procedures remained significant (Table 4).

«Planned home births result in low rates of interventions without an increase in adverse outcomes for mothers and babies,» Simkins boasts.

We used multiple regression to estimate the differences in total cost between the settings for birth and to adjust for potential confounders, including maternal age, parity, ethnicity, understanding of English, marital status, BMI, index of multiple deprivation score, parity, and gestational age at birth, which could each be associated with planned place of birth and with adverse outcomes.12 For the generalised linear model on costs, we selected a γ distribution and identity link function in preference to alternative distributional forms and link functions on the basis of its low Akaike's information criterion (AIC) statistfor birth and to adjust for potential confounders, including maternal age, parity, ethnicity, understanding of English, marital status, BMI, index of multiple deprivation score, parity, and gestational age at birth, which could each be associated with planned place of birth and with adverse outcomes.12 For the generalised linear model on costs, we selected a γ distribution and identity link function in preference to alternative distributional forms and link functions on the basis of its low Akaike's information criterion (AIC) statistfor potential confounders, including maternal age, parity, ethnicity, understanding of English, marital status, BMI, index of multiple deprivation score, parity, and gestational age at birth, which could each be associated with planned place of birth and with adverse outcomes.12 For the generalised linear model on costs, we selected a γ distribution and identity link function in preference to alternative distributional forms and link functions on the basis of its low Akaike's information criterion (AIC) statistFor the generalised linear model on costs, we selected a γ distribution and identity link function in preference to alternative distributional forms and link functions on the basis of its low Akaike's information criterion (AIC) statistic.

In further analyses restricted to women without complicating conditions at the start of care in labour, the adjusted odds of adverse perinatal outcomes were higher for births planned at home compared with those planned in obstetric units (adjusted odds ratio 1.59, 95 % confidence interval 1.01 to 2.52).

The paucity of evidence for the longer term consequences of adverse events and other health outcomes after birth for both mother and baby remains and further research to generate combined QALY estimates for the linked mother - baby dyad should be a priority for research in this specialty.

The results overall confirm the substantial health benefits of breastfeeding: it protects against a spectrum of adverse health outcomes for children, and breastfeeding mothers also gain from having breastfed.

Adverse neonatal outcomes including death were determined by place of birth and attendant type for in - hospital CNM, in - hospital «other» midwife, home certified nurse midwife, home «other» midwife, and free - standing birth center CNM deliveries.

Because negatively reactive temperament is relatively stable, it is proposed to have implications for more adverse, persistent outcomes than the transitory condition of colic.

Finally, because of the persistence of negative reactivity for some infants more adverse outcomes are likely, particularly if the parental environment is non-supportive.

Similarly, in a secondary analysis of 1,862 women enrolled in an early versus delayed pushing trial, a longer duration of active pushing was not associated with adverse neonatal outcomes, even in women who pushed for more than 3 hours (28).

This review suggests that women who received midwife - led continuity models of care were less likely to experience intervention and more likely to be satisfied with their care with at least comparable adverse outcomes for women or their infants than women who received other models of care.

Enabling women to breastfeed is also a public health priority because, on a population level, interruption of lactation is associated with adverse health outcomes for the woman and her child, including higher maternal risks of breast cancer, ovarian cancer, diabetes, hypertension, and heart disease, and greater infant risks of infectious disease, sudden infant death syndrome, and metabolic disease (2, 4).

These findings follow earlier research by Janssen that demonstrated that planned home births resulted in fewer interventions and similar rates of adverse newborn outcomes compared to planned hospital births among women who met the criteria for home births.

As for whether there were bad outcomes — OF COURSE the midwife would find out if there had been an adverse outcome.

It is based on plenty of cases where membranes were ruptured for more than 24 hrs, labour didn't progress and DESPITE foetal monitoring suggesting all was well there was an adverse outcome - usually chorioamnionitis, foetal sepsis or HIE.

In today's peer - reviewed Journal of Midwifery & Women's Health (JMWH), a landmark study confirms that among low - risk women, planned home births result in low rates of interventions without an increase in adverse outcomes for mothers and babies.

The last study is a British one, which accounted for socioeconomic factors, age, parity, smoking and BMI and still found an elevated risk of adverse maternal outcome for African and Carribean women.

«among low - risk women, planned home births result in low rates of interventions without an increase in adverse outcomes for mothers and babies.»

A comparison of adverse neonatal outcomes did not identify increased risk for babies born at home as part of the HBDP.

Maternal demographic and obstetric variables listed in Table 1 were examined for their role as confounders of associations with the prevalence of selected adverse outcomes using unconditional logistic regression.

Adverse outcomes were selected for multivariate analysis on the basis of clinical importance and sufficient numbers of outcomes with which to undertake a multivariate analysis.

The rates of some adverse outcomes were too low for us to draw statistical comparisons, and ongoing evaluation of home birth is warranted.

Overall, we did not find any increased likelihood for any adverse outcome for women or their infants associated with having been randomised to a midwife - led continuity model of care.

The safety of the nicotine patch therapy during pregnancy was assessed by monitoring for these adverse pregnancy events and birth outcomes.

«Our research indicates that insertion of cervical pessary at around 22 weeks in both randomly selected women pregnant with twins and in patients with a short cervix of less than 25 millimeters does not reduce the rate of spontaneous early preterm birth, perinatal death, adverse neonatal outcome, or need for neonatal therapy.»